Global, Local, vs Mask

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Last updated 3:50 AM on 9/21/26
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4 Terms

1
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Alignment

How we detect homology = two seq from common ancestor

2
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Global Alignment

1)X is a few plausible edits away from Y

3
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Local Alignment

2) If we trim off the ends, X and Y are similar in the sense of #1

4
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Masked Local Alignment

If we mask out the “boringly similar” parts (e.g. runs of repeated characters), they are similar in the sense of #2?