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Vocabulary-style flashcards covering key terms and their definitions from the notes on reproductive behavior.
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Sex (biological)
Biological status determined by chromosomes, gonads, and hormonal milieu (e.g., typical male XXY/XY patterns and associated development).
Gender
Identity and behaviors that may align with or differ from biological sex; a social/psychological construct.
Organizational effects
Permanent effects of early hormone exposure on tissue differentiation (brain, reproductive organs).
Activational effects
Temporary effects of hormones that activate certain physiological or behavioral processes in puberty or adulthood.
Gonads
Testes or ovaries; primary sources of sex hormones and gametes.
Internal sex organs
Embryonic derivatives such as Müllerian (female) and Wolffian (male) systems that form internal reproductive structures.
External sex organs
Genitalia such as penis, scrotum, clitoris, and vagina.
SRY gene
Sex-determining region of the Y chromosome; its presence initiates testis development.
Anti-Müllerian Hormone (AMH)
Hormone from fetal testes that inhibits the Müllerian system (defeminizing effect).
Androgens
Male hormones (e.g., testosterone) that masculinize development and promote Wolffian system formation.
Testosterone
Primary androgen; drives male development and secondary sex characteristics; precursor to DHT.
Dihydrotestosterone (DHT)
Potent androgen derived from testosterone; essential for external male genitalia development.
Turner’s syndrome
XO karyotype; typically female; often lacks functional ovaries and certain hormones.
Androgen insensitivity syndrome (AIS)
XY individual with testes but androgen insensitivity; external female or ambiguous genitalia; deficient masculinization.
Persistent Müllerian duct syndrome (PMDS)
XY individual with retention of Müllerian (female) internal structures despite androgen exposure.
Müllerian system
Embryonic precursors to female internal organs: fimbria, fallopian tubes, uterus, upper vagina.
Wolffian system
Embryonic precursors to male internal organs: epididymis, vas deferens, seminal vesicles.
Default female development
In absence of masculinizing hormones from testes, development tends toward female structures.
Sexual maturation
Pubertal development including the emergence of secondary sex characteristics and reproductive capability.
Secondary sexual characteristics
Physical features that distinguish sexes after puberty (e.g., breasts, facial hair, voice changes).
Gonadotropin-Releasing Hormone (GnRH)
Hypothalamic hormone that stimulates anterior pituitary to release FSH and LH.
Follicle-Stimulating Hormone (FSH)
Pituitary hormone that stimulates gamete production and ovarian follicle growth.
Luteinizing Hormone (LH)
Pituitary hormone that triggers ovulation and stimulates sex steroid production.
Kisspeptin
Neuropeptide that triggers GnRH release from the hypothalamus.
Estradiol
Major ovarian estrogen; promotes female development and regulates the menstrual cycle.
Puberty
Developmental stage marked by activation of the HPG axis and onset of reproductive capability.
Menstrual cycle
Monthly cycle in humans; endometrium thickens and sheds; ovulation occurs mid-cycle.
Estrous cycle
Reproductive cycle in non-primate mammals; endometrium reabsorbed if no pregnancy; mating linked to ovulation.
Endometrium
Uterine lining that thickens during the cycle and is shed if no pregnancy.
Corpus luteum
Rise from the ruptured follicle after ovulation; secretes estrogen and progesterone to maintain lining.
Progesterone
Hormone that maintains the uterine lining and supports early pregnancy.
Estrogen
Group of hormones (including estradiol) defining female sex characteristics and reproductive function.
Prolactin
Pituitary hormone essential for milk production and maternal behavior.
Maternal behavior
Behaviors such as nursing, licking, and grooming; modulated by MPOA and olfactory cues.
Medial preoptic area (MPA/POA)
Brain region critical for male sexual behavior and maternal behavior; integrates hormonal signals.
Ventromedial Hypothalamus (VMH)
Brain region linked to female sexual behavior and aggression; activity influences mating and other behaviors.
Medial amygdala
Brain region involved in processing pheromonal cues and social/sexual stimuli.
Periaqueductal Gray (PAG)
Midbrain structure involved in defensive and mating behaviors; part of sexual behavior circuits.
Fos protein
Protein used as a marker of neuronal activation after a behavior or stimulus.
Pheromones
Chemical signals that affect social/ reproductive behaviors; detected by the vomeronasal system.
Vomeronasal organ
Sensory organ for pheromones that projects to the amygdala and hypothalamus.
Optogenetics
Technique to control neuron activity with light using light-sensitive proteins.
Channelrhodopsin
Light-activated cation channel used to excite neurons in optogenetics.
Halorhodopsin
Light-driven chloride pump used to inhibit neurons in optogenetics.
Dopamine reward circuitry
Neural pathways that mediate motivation and reward, implicated in maternal and other behaviors.
Sexual orientation
Pattern of sexual attraction toward others; influenced by biology and experience.
Sexually dimorphic nuclei
Brain regions that differ between sexes and underlie behavioral differences.
See-saw control of mating and aggression
Balance where VMH activity modulates aggression in males and must be inhibited to allow mating.
Nucleus paragigantocellularis (nPGi)
Brainstem region that inhibits the spinal ejaculation generator via serotonin.
Lumbar spinothalamic tract (LSt)
Spinal network involved in ejaculation control.
Erection vs ejaculation control
Differentiated neural pathways; ejaculation often regulated by nPGi-LSt circuitry.