NAPLEX Vaccine + Travelers

The type of vaccine that does not have a good immune response in children < 2 years

polysaccharide

Polysaccharide vaccines do not have a good immune response in patients < ___ years

2

What type of vaccine is Pneumovax 23?

polysaccharide

Which type of vaccine increases immune response in infants?

conjugate

What type of vaccine is Prevnar 20?

conjugate

What type of vaccine is Menveo?

conjugate

Which type of vaccine is the most similar to the actual disease and provides a strong, long-lasting immune response?

live

Mneumonic for Live Vaccines

MICRO-VY

MICRO-VY for live vaccines

MMR

MICRO-VY for live vaccines

intranasal influenza

MICRO-VY for live vaccines

cholera

MICRO-VY for live vaccines

rotavirus

MICRO-VY for live vaccines

oral typhoid

MICRO-VY for live vaccines

varicella

MICRO-VY for live vaccines

yellow fever

Increasing the interval between the doses of a vaccine given in a series does not diminish the effectiveness after completion of the series, but it _______

delays complete protection

Decreasing the interval between doses of a vaccine can interfere with the _______

antibody response

______ can interfere with live vaccine replication and a separation period may be required

antibodies

The interval for separating MMR vaccine or Varicella vaccine between antibody products is _______

3-11 months

Most live vaccines are withheld until the child is _____ of age, when the maternal antibodies are depleted (maternal antibodies passed from mother to baby before birth reduce the infant’s response to live vaccines)

12 months

Which live vaccine is an exception to withholding till the child is 12 months of age and CAN be given to infants?

rotavirus

What type of vaccine can be given at any time?

inactivated

Which vaccine series is started at birth?

hepatitis B

Live vaccines can cause a false negative with tuberculin skin test (TST) for diagnosing latent TB. Options to reduce this risk are:

give the live vaccine on the same day as the TST, wait 4 weeks after a live vaccine to perform the TST, administer TST first and then give the live vaccine

Live vaccine and Antibody spacing:

Vaccine —> ______ —> antibody-containing product

2 weeks

Live vaccine and Antibody spacing:

Antibody-containing product —> ______ —> Vaccine

>= 3 months

Live vaccines can cause mild systemic reactions that can occur _____ after the vaccine is given (after an incubation period)

3-21 days

Which vaccine can cause mild cold-like symptoms, such as runny nose

intranasal influenza

Which vaccines are started at 2 months?

PCV15 or PCV20, DTaP, Hib, polio, rotavirus

Which vaccines are given at >= 12 months?

MMR, varicella

Which vaccines are given at 11-12 years?

meningococcal, HPV, Tdap

Which vaccines are given at pregnancy?

flu, RSV, Tdap

Which vaccines are given at >= 50 years?

shingles (herpes zoster vaccine), pneumococcal

Which vaccine is given at >= 75 years?

RSV

Which vaccine should be given in patients with diabetes?

pneumococcal (19-49 years), hep B (if >= 60 years and not previously vaccinated)

Shingrix has 2 doses that are given ________ apart

2-6 months

Meningococcal vaccine has 2 doses: 1 dose at age 11-12 years, and 1 dose at age ______ years

16

Pneumococcal vaccine is typically given in older adults (>= 50 years), but can be given in younger adults (19-49 years) if they have the following conditions:

diabetes, sickle cell disease + other causes of asplenia, immunodeficiency

Which vaccines are given in healthcare professionals?

flu (annually), Hep B, Varicella, MMR (if no demonstrated immunity)

Which vaccines are given in Sickle Cell Disease and other causes of asplenia?

Hib, pneumococcal, meningococcal

Which vaccines are given in immunodeficiency?

pneumococcal, shingles (herpes zoster vaccine) (>= 19 years)

Which vaccines are given in HIV patients (immunodeficiency)?

pneumococcal, shingles (herpes zoster vaccine) (>= 19 years), meningococcal, Hep A, Hep B

Pediarix

DTaP + Hep B + IPV

Havrix

Hep A

Vaqta

Hep A

What are the 3-dose Hep B vaccines?

Energix-B, Recombivax HB

What are the 2-dose Hep B vaccines?

Heplisav-B

Gardasil 9

HPV

When to use 2-dose series for Gardasil 9 (HPV)?

if started before age 15

When to use 3-dose series for Gardasil 9 (HPV)?

if started at age 15 or older

Afluria

flu shot for ages >= 6 months

Fluarix

flu shot for ages >= 6 months

FluLaval

flu shot for ages >= 6 months

Fluzone

flu shot for ages >= 6 months

Flucelvax

egg-free flu shot for ages >= 6 months

Flublok

egg-free flu shot for ages >= 18 years

Fluzone High-Dose

flu shot for ages >= 65 years

Fluad

flu shot for ages >= 65 years

FluMist

live intranasal flu vaccine

FluMist is for healthy people ages _______

2-49 years

ProQuad

MMR + Varicella

Which vaccines do you store in the freezer?

MMR, Varivax

MenQuadfi

MenACWY (meningococcal)

Menveo

MenACWY (meningococcal)

Bexsero

MenB (meningococcal)

Trumenba

MenB (meningococcal)

Penbraya

MenABCWY (meningococcal)

Capvaxive

PCV21 (pneumococcal)

Vaxneuvance

PCV15 (pneumococcal)

Rotarix

RV1 (rotavirus)

RotaTeq

RV5 (rotavirus)

Abrysvo

RSV vaccine

Beyfortus

Nirsevimab

Beyfortus drug class

RSV monoclonal antibody

Synagis

Palivizumab

Synagis drug class

RSV monoclonal antibody

Which vaccines are SC only?

yellow fever, dengue, smallpox, monkeypox

RabAvert

rabies vaccine

Which vaccines can be give IM or SC?

M-M-R II, MMRV, varicella, PPSV23, IPV

Which vaccines is given intranasal?

FluMist

Which vaccine is given PO?

typhoid, rotavirus

Vivotif

live PO typhoid vaccine

Which vaccine is stored in either the fridge or freezer?

M-M-R II

Prophylaxis for Traveler’s Diarrhea?

bismuth subsalicylate

The dose for Loperamide after the first stool is ____ mg, then it’s 2 mg after each subsequent loose stool, up to a max dose of 16 mg/day by Rx, or 8 mg/day OTC

4

The dose for Loperamide after the first stool is 4 mg, then it’s ___ mg after each subsequent loose stool, up to a max dose of 16 mg/day by Rx, or 8 mg/day OTC

2

The dose for Loperamide after the first stool is 4 mg, then it’s 2 mg after each subsequent loose stool, up to a max dose of _____ mg/day by Rx, or 8 mg/day OTC

16

The dose for Loperamide after the first stool is 4 mg, then it’s 2 mg after each subsequent loose stool, up to a max dose of 16 mg/day by Rx, or ____mg/day OTC

8

Loperamid can be used as self-treatment for up to _____ days, if sx persist, a healthcare provider should be seen

2

The antibiotics that can be used for TD are _______

azithromycin, quinolones, rifaximin

________ is the preferred antibiotic for severe TD + dysentery

azithromycin

Do not use BSS in patients with an ASA allergy, _______________

pregnancy, renal insufficiency, gout, ulcer, anticoagulants

Preferred antibiotic for TD ppx?

rifaximin

Typhoid fever is caused by the bacterium _______

salmonelle typhi

Typhim Vi

inactivated IM typhoid vaccine

Vivotif (live PO typhoid vaccine) should be completed ≥ _____ prior to travel

1 week

Typhim Vi (inactivated IM typhoid vaccine) should be completed ≥ _____ before the expected exposure

2 weeks

Cholera is a bacterial infx caused by _____

vibrio cholerae

Which traveler’s infection has “rice-water stools” as its most common sx (watery diarrhea)

cholera

Vaxchora

live PO cholera vaccine