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Lymphedema, Wound Pathophysiology, and Skin Screening.
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Lymphedema
Fluid stagnation and edema due to dynamic or mechanical insufficiency.
Superficial Lymphatics Target
MLD (Manual Lymphatic Drainage)
Lymph Organs Example: biggest lymph node
Cisterna Chyli
Lymphatic Capillaries Function
Connect to vessels to form drainage system, large and highly permeable
Lymph Fluid Composition
Clear and contains lymphatic load, part of immune system.
Lymph Flow Sequence
Lymph capillaries → precollectors → lymph collectors → lymph nodes → thoracic duct or right lymphatic duct → venous system.
Lymph Angions
Valves in lymph collectors with autonomic contraction.
Lymph Node Functions
Protection (filter), immune, thickening of lymph.
Anastomoses
Allow drainage from one lymphatic territory to another.
Etiology of Lymphedema
Fluid stagnation and edema.
Mechanical Insufficiency
Transport capacity decreases, often due to lymph node removal.
Dynamic Insufficiency
Lymphatic load exceeds transport capacity.
Primary Lymphedema
10% of cases, result of congenital malformation or impaired lymphatics.
Secondary Lymphedema
Most common caused by filiariasis (worldwide) or cancer-related (US).
Phlebolymphedema
Chronic venous insufficiency with lymphedema.
Lipedema
Disorder of adipose tissue.
Symptoms of Lymphedema
Heaviness, delayed wound healing, lymphorrhea, increased risk of infection, negatively impacts functional mobility.
Fibrosis
Buildup of collagen formation in later stages of lymphedema.
Lymphorrhea
Clear fluid that weeps from skin.
Risk Factors for Lymphedema
Surgical lymph node removal, radiation therapy, surgical complications, time since surgery, increased BMI, air travel, inflammation, decreased lymphatic return, scar tissue formation.
ISL Lymphedema Stage 0
Subclinical, no edema present, but impaired lymph transport.
ISL Lymphedema Stage 1
Early onset, fluid buildup may subside with elevation; pitting edema present.
ISL Lymphedema Stage 2
Elevation no longer helps, fibrosis present, frequent skin infections (cellulitis).
ISL Lymphedema Stage 3
Skin thickening, hyperpigmentation, papillomas.
PT Tests and Measures for Lymphedema
DASH, Lymphedema Life Impact Scale, LEFS, circumferential measures, ROM, strength, functional assessment.
Unilateral Edema Severity: Mild
<3 cm difference in circumferential measures
Unilateral Edema Severity: Moderate
3-5 cm difference in circumferential measures
Unilateral Edema Severity: Severe
5 cm difference in circumferential measures
Lymphedema PT Interventions
Patient education, therapeutic exercise, manual lymphatic drainage, compression garments/short stretch bandages, vasopneumatic compression pump.
Manual Lymphatic Drainage (MLD)
Should be performed by trained/certified individual.
MLD Main Points
Diaphragmatic breathing, proximal lymph node stimulation and clearing, proximal to distal clear and flow.
Importance of Self-MLD
Patient should be taught self-MLD and be an active participant in their treatment plan.
Compression Bandages
Multilayer short stretch compression bandages used during the reduction phase
Wound Etiologies
Abrasions, skin tears, de-gloving.
Abrasions
Caused by friction to the skin’s surface. Superficial or partial thickness
Skin Tears
Traumatic wounds resulting from shear or friction forces that separate the epidermis from dermis. Partial thickness wound. Example: Elderly at risk.
De-Gloving
When the skin is avulsed from underlying tissue.
Surgical Wound
Closed with stables, sutures, or tissue adhesives
Radiation-Induced Skin Damage
Directly/indirectly destroys tissue, inhibits inflammatory response & proliferative phase of healing.
Vasculitis
General term in reference to inflammation of blood vessels.
Pyoderma Granulosum
Non-infectious progressive necrotizing skin condition.
Cancer Causing Wounds
Skin cancers (squamous cell, basal cell, melanoma) as well as other cancers can cause wounds (colorectal, sarcomas, ovarian, lung, etc.)
Arterial Disease Process
Narrowing, distal extremities (think of frost bite=black gangrene)
Venous Disease Process
Leaky veins with hemosiderin staining.
Pressure Injury Process
Caused by tissue ischemia from pressure. DTI - don’t know depth of injury, just like pressure injury covered in black eschar.
Neuropathic Wound Process
Typically dying back neuropathy (stocking/glove); arteries hardened and potentially narrow.
Burns Pathophysiology
Thermal, Electrical, Chemical size: % TBSA or Lund and Browder Chart (more for pediatrics)
Skin Screening
Moles during exam, hemosiderin staining, lack of hair on legs, cold distal extremities
What to Consider with Lacking Blood Flow
Cuts off nutrients, oxygen to distal extremities then to necrosis
A1c Value Relation to Wounds
Need to understand; Hyperglycemia changes RBCs, platelets, and capillaries which alters blood flow and increases microvascular pressure
Immobilization Risk
At risk for developing wounds
Lack of Sensation
Unaware of injuries
Corticosteroids Risks
Weakened immune system, thinning skin
Sun Exposure Risk
At higher risk for skin cancers
Normal mole
A small brown spot or growth that appears in the first few decades of life. It can be flat or raised and generally is round.
Actinic Keratosis
The most common precancer, it's a small, crusty, bump. Colors vary. It can itch and bleed and can turn into squamous.
Dysplastic Nevi
These noncancerous moles resemble melanoma in color variation within the blemish and sometimes in their unusual shapes and border irregularities.
Basal Cell
This is the most common skin cancer. This nonlethal blemish can be a shiny bump, a pink growth, a scar-like area or an open sore that doesn't heal easily.
Squamous Cell
Persistent bleeding is common with this rarely deadly cancer. Warts, scaly patches, open sores and rapidly growing bumps are telltale signs.
Melanoma
This deadly cancer is usually larger than a pencil's eraser, multicolored and changes size and shape. Also look for asymmetry and uneven borders.
Lymphedema Definition
Swelling due to lymphatic system blockage
Manual Lymphatic Drainage Targets
Superficial lymphatic vessels
Cisterna Chyli Location
Abdomen
Lymph Capillaries Permeability
Highly Permeable
Lymph
Fluid in the Lymphatic System
Lymph Node
Filters Lymph
MLD Sequence Flow
Proximal To Distal
Filiariasis
Mosquito-born secondary cause of Lympedema
Lymphedema Stage 0 Symptoms
No edema, impaired lymph transport
Radiation Risk Factor
Decreased Immune Response
DASH and LEFS
Lymphedema PT test and measure
Circumferential Measurement Difference (Mild)
<3cm
Manual Lymphatic Drainage Therapist Qualification
Trained and Certified
Stockinette Use
During Lymphedema Reduction
ABI Test
Arterial Blood Flow
Venous Leg Ulcer Bandaging
Multilayer Compression
Superficial Wound Type
Abrasion
Skin Tear Cause
Shear and Friction Forces
Radiation skin damage
Inhibits inflammatory response and proliferative phase of healing
Vasculitis Symptoms
Purple or red spots or bumps, clusters of small dots or splotches, bruises, hives
Pyoderma gangrenosum characteristics
Progressive necrotizing skin condition; painful papule, vesicle, or pustule and progresses to full thickness ulceration; irregular boarders and undermining common.
Cancer atypical wound referral
Unusual location, Unusual wound bed texture, Atypical age group, Abnormal appearance of periwound tissue/skin
Gangrene caused by:
Arterial Disease
Hemosiderin Staining
Venous Leaks
Pressure Injuries
tissue ischemia from pressure
Neuropathic Foot Ulcers
Often on the sole of foot
Burns: Medical Management
Pain control, infection management, fluids, nutrition, covering the area (surgery), psychological health
Skin Screening
Moles during exam, hemosiderin staining, lack of hair on legs, cold distal extremities, Post-surgical patients
Extended Periods Immobility
Developing Wounds
Long-time Steroid Use:
Weakened immune system, thinning skin
Normal mole
Small brown spot or growth that appears in the first few decades of life. It can be flat or raised and generally is round.
Dysplastic Nevi
Noncancerous moles resemble melanoma in color variation within the blemish and sometimes in their unusual shapes and border irregularities.
Basal Cell
Most common skin cancer. Nonlethal blemish can be a shiny bump, a pink growth, a scar-like area or an open sore that doesn't heal easily.
Claudication
Symptoms of Arterial Disease Process
Volumetric Measurements
Measurements of Edema
Total Contact Casts
For Neuropathic Ulcers
Lund-Browder chart
Used to measure burns.
DTI
Don't know depth of injury of a pressure injury.
What to do before compression?
Rule out underlying arterial disease
Autonomic Contraction
Lymph Angions