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Q: What do mechanoreceptors respond to?
A: Physical force, such as touch and blood pressure.
Q: What do thermoreceptors respond to?
A: Temperature changes.
Q: What do photoreceptors respond to and where are they located?
A: Light; located in the retina.
Q: What do chemoreceptors respond to?
A: Specific molecules or ions (they bind and activate the receptor); involved in taste, smell, and fluid chemistry.
Q: What do nociceptors detect?
A: Harmful stimuli (pain).
Q: What are exteroceptors?
A: Sensory receptors that respond to external stimuli.
Q: What are interoceptors?
A: Sensory receptors that detect internal stimuli (e.g., blood pressure, internal organ sensations).
Q: What are proprioceptors?
A: Receptors located in muscles, tendons, and ligaments that detect stretch and body position.
Q: What distinguishes general senses from special senses?
A: General senses are non-localized and widespread; special senses have dedicated structures (e.g., taste receptors on the tongue).
Q: Is touch a general or special sense?
A: General sense.
Q: What are nonencapsulated receptors and where are they found?
A: Free nerve endings without protective structures, found in epithelial and connective tissues.
Q: What are Merkel cells, and what do they detect?
A: Nonencapsulated, exteroceptive mechanoreceptors that detect light pressure. They adapt slowly and are located in the basal epidermis (stratum basale).
Q: What do hair follicle receptors detect, and how do they adapt?
A: They detect movement of hair and are rapidly adapting mechanoreceptors.
Q: What are encapsulated receptors?
A: Receptors enclosed in connective tissue that help refine the stimulus.
Q: What are tactile corpuscles (Meissner’s corpuscles) sensitive to?
A: Light touch and low-frequency vibration. They are rapidly adapting and concentrated in hairless skin (e.g., palms, fingertips).
Q: What are lamellar corpuscles (Pacinian corpuscles) sensitive to?
A: Deep pressure, stretch, and high-frequency vibrations. Found in the dermis.
Q: What do muscle spindles detect?
A: They are proprioceptors that sense muscle stretch and length.
Q: What do tendon organs detect?
A: They are proprioceptors that sense tendon stretch, acting as a protective mechanism during muscle contraction.
Q: What is the basic organization of sensory input to perception?
A: Receptor → neural circuit → perception (awareness from frontal/prefrontal cortex).
Q: What is specificity in sensory receptors?
A: Each receptor responds only to a specific type of stimulus (e.g., photoreceptors respond only to light).
Q: What is a receptive field?
A: The area or range of stimuli a sensory receptor can detect.
Q: What is adaptation in sensory receptors?
A: A decrease in sensitivity to a constant stimulus over time.
Q: What are tonic receptors?
A: Receptors that do not adapt; they continuously send signals.
Examples: Proprioceptors, Nociceptors.
Q: What are phasic receptors?
A: Receptors that adapt quickly to a constant stimulus.
Q: What is projection in sensory processing?
A: The concept that specific receptors always activate the same region in the cortex, leading to consistent perception.
Q: What is perceptual detection?
A: The ability to detect that a stimulus occurred, often requiring multiple receptors.
Q: What is magnitude estimation?
A: Perception of the intensity of a stimulus.
Q: What is spatial discrimination?
A: The ability to identify the exact location of a stimulus.
Q: What is feature abstraction?
A: Recognizing specific features (e.g., texture, shape) of a stimulus.
Q: What is quality abstraction?
A: Differentiating between submodalities within a sense (e.g., bitter vs sweet in taste).
Q: What is pattern recognition?
A: The ability to recognize familiar patterns, such as a face or melody, using memory.
Q: What does the presence of potassium (K⁺) ions outside of a cell indicate?
A: It suggests cellular damage, triggering pain responses via receptor activation.
Q: What are the two types of nerves based on origin?
A: Cranial nerves (from the brain) and spinal nerves (from the spinal cord).
Q: What do motor (efferent) nerves do?
A: They carry signals away from the CNS to effectors (muscles or glands).
Mnemonic for functions:
S = Sensory, M = Motor, B = Both
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CN I – Olfactory
Q: What is the function of the olfactory nerve?
Smell
CN I – Olfactory
Q: What’s unique about CN I's pathway?
A: Bypasses the thalamus, and is exposed to the external environment.
CN I – Olfactory
Q: What is anosmia?
A: Loss of smell, often due to damage to CN I.
CN II – Optic
Q: What is the pathway of the optic nerve?
A: Retina → Optic canal → Optic chiasma → Thalamus → Visual cortex (occipital lobe)
CN III – Oculomotor
Q: What muscles does the oculomotor nerve control?
A: 4 of 6 extrinsic eye muscles, iris (pupil constriction), ciliary body (lens focus).
CN III – Oculomotor
Q: Where does it originate and exit?
A: Starts in ventral midbrain, exits via superior orbital fissure.
CN IV – Trochlear
Q: Which muscle is innervated by the trochlear nerve?
A: Superior oblique muscle (eye rotation).
CN IV – Trochlear
Q: Where does it originate and exit?
A: Dorsal midbrain → Superior orbital fissure
CN V – Trigeminal
Q: What is the function of the trigeminal nerve?
A: Facial sensation and mastication (chewing).
CN V – Trigeminal
Q: What are its 3 main branches?
A: Ophthalmic (cornea), Maxillary, Mandibular (chewing muscles).
CN VI – Abducens
Q: What muscle does the abducens nerve control?
A: Lateral rectus muscle (eye abduction).
CN VI – Abducens
Q: Where does it originate and exit?
A: Inferior pons → Superior orbital fissure
CN VII – Facial
Q: What are the motor functions of the facial nerve?
A: Facial expressions, parasympathetic control of lacrimal, nasal, and salivary glands.
CN VII – Facial
Q: What are the sensory functions?
A: Taste (sweet, salty, sour, bitter) from anterior 2/3 of the tongue.
CN VIII – Vestibulocochlear
Q: What does the vestibulocochlear nerve do?
A: Hearing and balance from the inner ear.
CN VIII – Vestibulocochlear
Q: Does the vestibulocochlear have a motor function?
A: Yes, limited motor to protect inner ear by adjusting sensitivity.
CN IX – Glossopharyngeal
Q: What are its motor functions?
A: Swallowing, salivary gland activation, regulation of blood chemistry via carotid body.
CN IX – Glossopharyngeal
Q: What are its sensory functions?
A: Taste and touch on the posterior 1/3 of the tongue and throat.
CN X – Vagus
Q: What are its motor functions?
A: Swallowing and parasympathetic control of heart, lungs, and viscera.
CN X – Vagus
Q: What are its sensory functions?
CN XI – Accessory
Q: What muscles does the accessory nerve innervate?
A: Neck and shoulder muscles (e.g., trapezius, sternocleidomastoid).
CN XI – Accessory
Q: Does it have a sensory component?
A: Minor proprioception from those muscles.
CN XII – Hypoglossal
Q: What does the hypoglossal nerve control?
A: Tongue movements essential for speech, chewing, and swallowing.
Q: What is Cranial Nerve I? (Name, function, sensory/motor)
A: Olfactory – Smell – Sensory
Q: What is Cranial Nerve II? (Name, function, sensory/motor)
A: Optic – Vision – Sensory
Q: What is Cranial Nerve III? (Name, function, sensory/motor)
A: Oculomotor – Eye movement (4/6 muscles), pupil constriction, lens shape – Motor
Q: What is Cranial Nerve IV? (Name, function, sensory/motor)
A: Trochlear – Eye movement (superior oblique muscle) – Motor
Q: What is Cranial Nerve V? (Name, function, sensory/motor)
A: Trigeminal – Facial sensation, chewing – Both
Q: What is Cranial Nerve VI? (Name, function, sensory/motor)
A: Abducens – Eye movement (lateral rectus muscle) – Motor
Q: What is Cranial Nerve VII? (Name, function, sensory/motor)
A: Facial – Facial expressions, taste (anterior 2/3 tongue), salivary/lacrimal glands – Both
Q: What is Cranial Nerve VIII? (Name, function, sensory/motor)
A: Vestibulocochlear – Hearing and balance – Sensory
Q: What is Cranial Nerve IX? (Name, function, sensory/motor)
A: Glossopharyngeal – Taste (posterior 1/3 tongue), swallowing, salivation, blood chemistry – Both
Q: What is Cranial Nerve X? (Name, function, sensory/motor)
A: Vagus – Parasympathetic control of heart/lungs/viscera, swallowing, visceral sensation – Both
Q: What is Cranial Nerve XI? (Name, function, sensory/motor)
A: Accessory – Shoulder and neck movement (sternocleidomastoid, trapezius) – Motor
Q: What is Cranial Nerve XII? (Name, function, sensory/motor)
A: Hypoglossal – Tongue movement (speech, chewing, swallowing) – Motor
Q: Are spinal nerves sensory, motor, or both?
A: Both afferent (sensory) and efferent (motor).
Q: What does the dorsal root of a spinal nerve carry?
A: Sensory (afferent) fibers.
Q: What does the ventral root of a spinal nerve carry?
A: Motor (efferent) fibers.
Q: Where are sensory neuron cell bodies located?
A: In the dorsal root ganglion.
Q: What kind of nerve is a spinal nerve?
A: Short and mixed (contains both sensory and motor fibers).
Q: What do spinal nerves split into after exiting the spinal cord?
A: Rami (anterior and posterior), which are mixed.
Q: What does the posterior ramus innervate?
A: Skin and muscles of the back.
Q: What does the anterior ramus innervate?
A: Anterior/lateral body wall and limbs.
Q: What connects spinal nerves to the sympathetic nervous system?
A: Rami communicantes.
Q: What is a plexus?
A: A network of interconnecting spinal nerve fibers.
Q: What is the function of the cervical plexus?
A: Innervates skin of the neck (cutaneous nerves).
Q: What does the phrenic nerve innervate?
A: The diaphragm.
Q: What condition is linked to phrenic nerve damage?
A: Respiratory paralysis.
Q: What area does the brachial plexus serve?
A: The upper limb.
Q: What does the axillary nerve innervate?
A: Deltoid and teres minor muscles.
Q: What does the musculocutaneous nerve innervate?
A: Biceps and other anterior arm muscles.
Q: What does the median nerve control?
A: Forearm and thumb muscles.
Q: What does the radial nerve control?
A: Wrist extensor muscles.
Q: What does the ulnar nerve control?
A: Hand muscles; known as the "funny bone."
Q: Which nerves serve the forearm?
A: Median, radial, and ulnar nerves.
Q: What area does the lumbar plexus supply?
A: Anterior thigh and lower abdomen.
Q: What does the femoral nerve innervate?
A: Quadriceps and hip flexors.
Q: What does the obturator nerve innervate?
A: Thigh adductor muscles.
Q: What area does the sacral plexus serve?
A: Posterior thigh and lower leg.
Q: What is the largest nerve in the body, and what does it branch into?
A: Sciatic nerve; branches into the fibular and tibial nerves.
Q: What does the coccygeal nerve control?
A: Sensation around the tailbone.
Q: What are dermatomes used for in clinical practice?
A: To determine nerve blocks for anesthesia.
Q: What are motor endings for skeletal muscles called?
A: Neuromuscular junctions (NMJs).
Q: What are motor endings at visceral effectors called?
A: Synapses en passant.
Q: What neurotransmitter is released at the NMJ?
A: Acetylcholine (ACh).