HD DOHAD Epigenetics and Imprinting
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4 Terms
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Epigenetics
A set of mechanisms, including chemical modifications to DNA and associated structures, that regulate gene function without changing the DNA sequence.
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Imprinting Disorders
Genetic conditions caused by abnormal gene expression due to epigenetic mechanisms, where only one allele (maternal or paternal) is expressed.
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DNA Methylation
The addition of a methyl group to DNA, typically at cytosine bases, which can regulate gene expression.
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Uniparental Disomy (UPD)
A genetic condition where both copies of a chromosome are inherited from one parent, leading to potential imprinting disorders.
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