Eukaryotic Gene Expression

Flashcards covering key concepts of Eukaryotic Gene Expression.

Eukaryotic gene expression is modified at stages of gene expression, not predominantly just transcription.

all

DNA __ and modification of chromatin structure can influence the transcription of genes in an epigenetic manner.

methylation

Epigenetics is the study of mechanisms that lead to changes in gene expression that can be __ from cell to cell and are reversible.

passed

DNA __ may be attached to cytosine bases in DNA, which, when near promoters, usually inhibits transcription.

methylation

Changes in chromatin structure can affect the ability of transcription factors to gain access to and to their target sequences.

bind

Heterochromatin is tightly packed and genes are __, while euchromatin is lightly packed and genes are expressed.

not expressed

___ removes acetyl groups from histones, limiting transcription.

Histone deacetylases

Enhancers and __ can act over relatively long distances to influence gene expression.

silencers

Micro-RNA (miRNA) can cause translational repression of mRNA or mRNA __.

degradation

The inactive X chromosome in female mammals is extensively __ and associated with transcriptional repression.

methylated