Pregnancy, Box Warnings, ADR Fall

Amoxicillin

ADR - Nausea

Diarrhea

Amoxicillin; Clavulanate Potassium

ADR - Nausea

Diarrhea

Azithromycin

ADR - N/V/D

Cefdinir

ADR - Diarrhea

Cephalexin

ADR - Nausea

Ciprofloxacin

Preg - *Contraindicated

Box - May exacerbate muscle weakness in patients with myasthenia gravis, tendon inflammation and rupture, peripheral neuropathy, CNS effects, cardiac, dermatologic and hypersensitivity reactions, aortic dissection and rupture, hypoglycemia, mental health adverse effects

ADR - Tooth discoloration in infants

Musculoskeletal signs

Clindamycin

Box - Colitis

ADR - Nausea

Topical: Dry Skin

Doxycycline

Preg - *Contraindicated 2nd & 3rd

ADR - Esophageal injury

Photosensitivity

Skin Hyperpigmentation

Tooth discoloration in <8yo

Levofloxacin

Preg - *Contraindicated

Box - Myasthenia gravis, tendon inflammation and rupture, peripheral neuropathy, CNS effects, cardiac, dermatologic and hypersensitivity reactions, aortic dissections and ruptures

ADR - Photosensitivity

Nitrofurantoin

ADR - Discoloration of urine

Sulfamethoxazole; Trimethoprim

ADR - Diarrhea

Nausea

Acyclovir

ADR - Malaise

Fluconazole

ADR - Headache

Ketoconazole

ADR - Application site reaction with foam

Metronidazole

Box - Carcinogenic
ADR - Headaches
Nausea

Mupirocin

ADR - Burning, stinging, and pain

Oseltamivir Phosphate

ADR - Nausea
Vomiting
Headache

Valacyclovir

ADR - Malaise
Headache
Nausea
Nasopharyngitis
Neutropenia
Increased LFTs

Amlodipine

ADR - Peripheral edema
Pulmonary edema

Atenolol

Box - Avoid abrupt withdrawal

ADR - Hypotension
Dizziness
Fatigue
Cold extremities
Depression
Bradyarrhythmias

Benazepril Hydrochloride

Box - Pregnancy, fetal toxicity
ADR - None Common - Dizziness, fatigue, headache, nausea

Carvedilol

ADR - Hypotension
Dizziness
Fatigue
Cold extremities
ED
Weight gain

Enalapril Maleate

Box - Pregnancy
ADR - Increased SCr

Furosemide

Box - Fluid and electrolyte loss
ADR - Hyperuricemia

Potassium Chloride

ADR - Nausea
Indigestion
Flatulence

Hydrochlorothiazide

ADR - Dizziness
Hypotension
Headache

Irbesartan

Box - Pregnancy
ADR - Hyperkalemia

Labetalol

ADR - Dizziness
Fatigue
Nausea

Lisinopril

Box - Pregnancy
ADR - None Common - Dizziness, fatigue, headache, nausea

Losartan Potassium

Box - Pregnancy
ADR - Headache

Metoprolol

Box - Ischemic heart disease with abrupt withdrawal
ADR - Hypotension
Dizziness
Fatigue

Nebivolol Hydrochloride

ADR - None common - Diarrhea, dizziness, headache

Olmesartan

Box - Pregnancy
ADR - None common - dizziness

Propranolol Hydrochloride

ADR - Hypotension

Ramipril

Box - Pregnancy
ADR - None Common - Dizziness, fatigue, headache, nausea

Valsartan

Box - Pregnancy
ADR - Dizziness
Increased BUN

Chlorthalidone

ADR - Dizziness
Hypotension
Hyperuricemia

Clonidine

Box - Epidural use
ADR - Feeling nervous
Headache
Somnolence
Xerostomia
Erythema (patch)

Diltiazem Hydrochloride

ADR - Edema
Headache

Guanfacine

ADR - Drowsiness
Headache
Dizziness
Insomnia
Anorexia

Hydralazine Hydrochloride

ADR - No major side effects

Hydrochlorothiazide; Lisinopril

Box - Pregnancy
ADR - Dizziness
Hypotension
Headache

Hydrochlorothiazide; Losartan Potassium

Box - Pregnancy
ADR - Dizziness
Hypotension
Headache

Hydrochlorothiazide; Triamterene

Box - Hyperkalemia
ADR - Dizziness
Hypotension
Headache

Nifedipine

ADR - Flushing
Headache
Peripheral edema
Dizziness
Weakness
Nausea
Dyspepsia

Prazosin

ADR - Dizziness

Valsartan/Sacubitril

Box - Pregnancy
ADR - Hypotension, hyperkalemia, increased SCr

Spironolactone

Box - Tumorigenic in animal models
ADR - No major side effects - dizziness

Verapamil Hydrochloride

ADR - Gingival hyperplasia

Amiodarone Hydrochloride

Box - Arrhythmias, hepatotoxicity, proarrhythmic effects, pulmonary toxicity
ADR - Nausea
Vomiting
Phospholipidemia

Apixaban

Box - Premature discontinuation increases risk of thrombotic events; increased risk of spinal hematoma with spinal puncture or neuraxial anesthesia
ADR - Bleeding

Atorvastatin

Preg - Contraindicated- 1st trimester
ADR - Myopathy
Diarrhea
Headache
Nasopharyngitis

Clopidogrel Bisulfate

Box - Reduced CYP2C19 function
ADR - Headache

Ezetimibe

Preg - CI concurrent use with statin in pregnant people
ADR - No major side effects

Fenofibrate

ADR - Hyperhomocysteinemia

Isosorbide Mononitrate

ADR - Dizziness
Headache

Lovastatin

Preg - Contraindicated - 1st trimester
ADR - Myopathy
Diarrhea
Headache
Nasopharyngitis

Nitroglycerin

ADR - Headache

Pravastatin Sodium

Preg - CI in 1st trimester
ADR - Myopathy
Diarrhea
Headache
Nasopharyngitis

Rivaroxaban

Box - Premature discontinuation increases thrombotic risk, risk of spinal/epidural hematoma
ADR - Bleeding

Rosuvastatin

Preg - CI in 1st trimester
ADR - Arthralgia

Sildenafil

ADR - Flushing, nausea, headache, visual disturbances, lack of blue/green color discrimination

Simvastatin

Preg - CI in 1st trimester
ADR - Myopathy
Diarrhea
Headache
Nasopharyngitis

Warfarin

Preg - Contraindicated - 1st trimester
Box - Bleeding
ADR - Bleeding