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What is Hemostasis?
The correct balance of all systems in the body
Keeping body in regulated limites
Do Geriatric population have a low or high body water %
Lower, meaning they are more suseptible to fluid/ Electrolyte imabalnces
What are examples of Intracellular Fluid (ICF)
Leukocytes, RBC, Platelets
What are examples of Extracellular fluids
Interstitial
Intravascular
Transcellular
Does Intracullular fluid make up 2/3 of the body fluid
Yes
Does Extracellular Fluid make up 1/3 of the bodies fluid?
Yes
What is the interstitial fluid of ECF?
Fluid located Between spaces between cells and lymph
What is intravascular fluid of the ECF?
All blood
Blood Plasa
Blood components (WBC, RBC
What type of ECF is Blood?
Intravascular
What is Transcellular fluid of the ECF?
Fluids in special locations surrounded by epitheial membrands
Cerebrospinal fluid
GI fluids
Joint Fluids
Pleural
Peritoneal
Intraocular
Pericardial
What are electrolytes
Minerals that carry a charge when dissolved in water.
What are the common electrolytes in ICF fluid (Salty Banana)
K+
Phosphate PO4 -3
What are the comon electrolytes in ECF
NaCL
What charge are Cations
Positive
What charges are Anions
Negative
What is the unit for concentration of electrolytes?
Milliequivalents
(mEq)/L
What is Diffusion?
Movement of molecules across a permable membrane from high to low concetration
Movement stops when both sides have the same concentration
What is Facilitated diffusion
The use of carrier molecules to be able to move molecules from high to low
Passive
What is osmosis?
Water moving down the concentration gradient (Refering to concentration of water)
Moving from low solute to high solute
Does osmosis require energy
no
What is Osmotic Pressure?
The amount of pressure it takes to stop osmosis from naturally happening
What is osmolarity?
The total particles per liter of solution
What is Osmolality?
Total partciles per kilogram of water
Whats the difference betweem osmolarity and osmolality?
Osmolarity: total particles per liter of solution (IV bags)
Osmolality: Total particles per kilogram of water (Labs)
What are the normal values for normal plasma osmolality?
280-295 mOsm/kgs this
What does a value >295 mean for plasma osmolality? What happens
High Osmolality: Water Low, Solutes high
Water is pulled from surrounding cells causing cell shrinkage and cell drhydration
Blood pressure briefly increases
What does a value <280 mean for plasma osmolality?
Low osmolarity: High Water, Low solute
Water is pushed from plasma to surrouding cells causing swelling.
What is hydrostatic pressure.
Pressure built inside vessel that causes water to be pushed outside of the vessel into interstitial space
Whats the difference between hydrostatic pressure and osmotic pressure?
Hydrostatic pressure pushes water out of the vessels
Osmosis brings water into the vessels via albumin
What is the % of human cells
0.9% salt concetration
What do Isotonic fluids do to cells? What concentration are they
Cell remains the same due to equal solute concentration
0.9% NS, Lactated Ringers
What do hypotonic fluids do to cells? What concentration are they?
Cells swell because of osmosis leading fluid from low to high
Solute of solution is less than cell solute
Anything less than 0.9%
What do hypertonic fluids do to cells? What Concentration are they?
Causes water from cells to leave, Cells shrink
Solution has higher solute concentration compared to cells
Higher than 0.9%
Is hydrostatic pressure built from blood pressure
Yes,

What happens in the arterial end vs the venous end
Arterial end: New highly pressurized blood arrives increase the hydrostatic pressure causing water to leak out to surrounding tissue
Venous end: Water comes back to the vessel due to decrease hydrostic pressure
What are the causes of Edema?
Plasma moving from vessels to interstial space
Elevated venous hydrostatic pressure (its usally low to get water back in)
Decreased Plasma Oncotic Pressure (can’t keep water in)
Elevation of interstial oncotic pressure
What organ produces albumin
The liver
What ist he usual cause for decrease onotic pressure
Lack of albumin
Can burns cause damage to capillary walks increasing capillary permeability allowing proteins and albumin to leak to interstitial spaces
Yes
What is first spacing for fluids.
Fluids are where they are supposed to be in the ECF and the ICF
What is second spacing?
Abnormal accumulation of fluid in interstitial space
Edema
What is Third spacing?
Fluid gets trapped in areas where is it impossible/difficult to remove back to its normal area
Ascites
Pleural effusion
Usually have to surgicaly drainded
How does the hypothalamic pituitary regulation work for water balance
Osmoreceptors in the hypothalamus detect fluid imbalances
If low: Stimulate Thirst, release ADH
If high: Stop ADH
What is Syndrome of inappropriate antidiuretic hormone secretion (SIADH)?
The body releases excess amounts of ADH causing severe fluid retention
Is it true that the kidneys are the primary organs for regulating fluid balance, electrolyte levels, and urine volume?
Yes
What does aldosterone do?
Increases Reabsorbation of Na: allowing water to be retained
Excretes K+
How does stress affect fluid and electrolyte balance?
Activates ADH
increase Water reabsoption
Activates aldosterone
Increase cortisol
What do Natriuretic peptides do?
Serve as antagnoist to the RAAS system to decrease blood volume and pressure to stop Heart from being overstretched
Made by heart
How is most water introduced to the body
Orally
Is it true that small amounts of water are eliminated by the GI tract in feces
Yes, most of water gets reabsorbed
Why does diarrhea and vomited lead to significant fluid and electrolyte loss?
Because of the consistancy itself, and being the GI system has not finished it’s job therefore stools are not fully formed
How many ml of digestive fluid is secreted by the GI tract?
8,000 ml
Geriatric populations suffer from
Structural changes in kidney that affect the ability to conserve water
Hormone changes causing renin, aldosterone decrease
Increase in ADH and ANP
Decreased Thirst sensation

What does skin turgor test for?
Hydration status:
Normal Finding: Skin goes back into in 2 seconds
Abnormal (tenting): Skin stays folded due to lack of water

For older adutls why is skin turgor a cautious test?
Can give false result due to loss of tissue elasticity leading to false results
What does Hypovolemia mean?
It is a fluid volume deficit (FVD)
What is Hypovolemia caused by
Abnormal loss of body fluids, inadequate fluid intake, or plasma or interstitial fluid shift
Loss of both water and electrolytes
What is dehydration
Loss of pure water only
No loss of electrolytes
What are health history items that could indicate fluid imalances?
Kidney, Heart, Gi , Respiratory issues
Body weight flucuations
Dialysis
Activity level
What are some causes for a fluid volume deficit?
Vomiting, Diarrhea, Hemorrhage
Polyuria
3rd space shifts
What are some causes of hypervolemia
Excess fluid intake
Abnormal fluid retention
Interstitial to plasma fluid shift
What is a common clinical manifestation of hypervolemia?
Weight Gain
What are some nursing issues that can hpapen when theres hypervolemia?
Impaired gas exchange
Impaired tissue integrity
Activity intolerance
What are some nursing actions to manage fluid imblanaces
Daily weights
Monitor Intake and Output
What is the number for concentrated urine specific gravity
>1.025
What is the number for diluted urine specific gravity?
<1.010
What are some cardiac signs of hypervolemia?
Increase Pulses
Jugular Vein Distention
Presence of S3 heart sound

What are some cardiac signs of hypovolemia
Early sign: Increase Pulse
Late: decrease urine output
What pressure increases that acuses fluid build up in the alveoli?
Hydrostatic
What are the nursing problems of low BP
Blurred vision
Loss of concentration
Dizziness
Nausea
What are nursing interventions for low BP
Evidence Base Fall risk protocol
Monitor for orthostatic changes
Bed Alaram
Assess LOC, Gait, Muscle Strength
What labs would you expect for someone who is hypovolemic?
Elevated BUN, Sodium, Hematocri
High olmolality for plasma (>295) and urine test
What labs would you expect for someone who is hypervolemic
Decreased BUN, Sodium, hematocrit
Decreased plasma (<275) and urine osmolality
Elevated BNP (Natriuretic Peptide)
What is sodium mainly used for in the body
Regulate Fluid Balance
Transmit nerve signals
Muscle Contractions
Regulating acid base balance
Is it true that when sodium changes happen, plasma osmolality also changes
Yes
What are some clinical manifestations of Hypernatremia?
Thirstiness
Any manifestations of low BP
Symtoms associated with Fluid Volume Deficiencies
What are the usual causes of Hypernatremia? What population is at risk
Inadequate water intake
Confused paitents are at risk as well as older
What are some treatments for hypernatermia?
Replace fluid orally or IV with isotonic or hypotonic fluids
Use sodium free IV fluids and promote sodium excretion with diuretics