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Red blood cells
contain hemoglobin necessary for oxygen transport
Normal Red blood cells
4-6 mill/mm3
Low RBC
anemia
occurs with blood loss, hemorrhage
High RBC
polycythemia
occurs with chronic tissue hypoxemia
Hemoglobin
carries oxygen 1.34 mL per gram Hb
Normal hemoglobin value
12-16
Low hemoglobin
referred to as anemia
High hemoglobin
referred to as polycythemia
Hematocrit ( Hct )
Spin the whole blood and measure the % of RBC in the original blood volume
Hematocrit Normal value
40-50%
Low Hematocrit is referred to as
asthma
High Hematocrit is referred to as
polycythemia
White blood cell count changes in response to
infections
Normal value of WBC
5,000- 10,000
Increased WBC ( leukocytosis ) indicates
a bacterial infections best to recommend antibiotics
Decreased WBC ( leukopenia ) indicates
a viral infection best to recommend antiviral agents
Neutrophils
Major WBC
has bands and segs
Bands
immature cells normally 4% of WBC; increased with bacterial infections
Segs
mature cells; normally 60% of WBC ; decreased with bacterial infections
Eosinophils
associated with asthma ; 2% of WBC increased with allergic reactions
Monocytes
associated with tuberculosis ; 3% of WBC
Lymphocytes
30% of WBC
Basophils
1% of WBC
Potassium ( K+ )
important for acid base balnce and muscle function, including cardiac muscle
Normal range for potassium
3.5 - 4.5
Hypokalemia refers to
low K+ and it occurs with metabolic alkalosis, excessive excretion, vomiting, flattened T waves on ECG
Sodium ( Na + )
Major intracellular cation controlled by kidneys
Sodium normal range
135-145
Hyponatremia refers to
low Na+ can be due to fluid loss from diuretics, vomiting, diarrhea, fluid gain from CHF, IV therapy
Hyperkalemia refers to
High potassium, due to kidney failure, spiked T wave ( metabolic acidosis )
Hypernatremia refers to
High Na+ due to dehydration
Na+ is retained in exchange for
K+
Chlorine
Major extracellular anion
Chlorines levels are associated with
sodium
Chlorines normal range is
90-100
Hypochloremia refers to
Low Cl ( metabolic alkalosis )
Hyperchloremia refers to
High Cl ( metabolic acidosis )
Bicarbonate HCO3
Most of the CO2 in the blood is carried as HCO3 so that changes in total CO2 content reflect changes in blood base
Increased CO2 content reflects Increased HCO3 leads to
Metabolic alkalosis
Decreased CO2 content reflects decreased HCO3
Leading to metabolic acidosis
Increased PCO2 leads to
Respiratory acidosis
Decreased PCO2 leads to
Respiratory alkalosis
Creatine
excreted by kidneys
evaluates kidney function
Creatine normal values
0.7 to 1.3 mg/dL
Blood urea nitrogen ( BUN )
evaluates kidney function
increased BUN indicates kidney failure
Blood Urea nitrogen normal value
8-25 mg/dL
Mucoid sputum
white and gray
indicates chronic bronchitis
Yellow sputum
presence of WBC ( eosinophils )
indicates bacterial infection
Green sputum
Stargant sputum, gram negative bacteria
indicates bronchiectasis, pseudomonas
Brown Dark sputum
Old blood,
anaerobic lung infection
Bright red sputum
Hemoptysis
bleeding tumor, TB
Pink Frothy Sputum
Pulmonary Edema
Sputum culture
Identifies the bacteria present, takes 48 to 72 hours
Sensitivity
Identifies what antibiotics will kill the bacteria, takes 48 to 72 hours
Gram stain
Identifies whether bacteria are gram positive or gram negative, takes an hour
Acid fast stain
identifies mycobacterium tuberculosis
Normal platelet count
150,000- 400,000 mm3
Decreased platelet count indicates
values associated with decreased bone marrow function and sepsis
Activated partial thromboplastin time
measures the length of time required for plasma to form a fibrin clot
used to monitor heparin therapy
Activated Partial Thromboplastin time normal value
24-32 secs
Prothrombin time
used to monitor warfarin ( coumadin ) therapy
Normal value for prothrombin time
12-15 seconds
Urinalysis
Reflects metabolic status of patients and is a screening test for kidney disease
can indicate urinary tract infections before blood culture results
also measures appearance, specific gravity, pH, glucose, ketones, blood bilirubin and sedimentation
Troponin
Specific indicator of damage to heart muscle
pt who has suffered a myocardial infarction would have elevated troponin levels
Troponin levels > 0.1 place the pt at
high risk for a death from MI
recommend oxygen, morphine, aspirin, nitroglycerin
Brain Natriuretic Peptide ( BNP )
Secreted by the cardiac muscle when heart failure develops or worsens
measurement if serum BNP is helpful to determine if the pts symptoms are the result of CHF or another condition indicate CHF
Normal BNP value
< 100 pg/mL
> 300 pg/mL may indicte
mild heart failure
> 600 pg/mL may indicate
moderate heart failure
> 900 pg/mL may indicate
severe heart failure
Normal axis is in a direction of
down and to the left
Hypertrophy
increases electrical activity, axis will shift toward hypertrophy
Infarction
dead tissue, no electrical acitivity, axis will shift away from infarction
When the electrical impulse of the heart moves toward the positive electrode
an upward deflection is made on the ECG paper
There are 12 leads used
6 limb leads
6 precordial chest leads
10 electrodes
Lead 1
left arm positive and right arm negative
Lead 2
left leg positive and right arm negative
Lead 3
left leg positive and left arm negative
AVR
right arm positive and everything else is negative
AVL
left arm positive and everything else is negative
AVF
left leg is positive and everything else is negative
V1
4th intercostal space on the right side of sternum
V2
4th intercostal space on the left side of the sternum
V3
Between V2 and V4 on the left side
V4
5th intercostal space, left mid clavicular line
V5
Between V4 and V6 on the left side
V6
5th intercostal space, left mid- axillary line
Flutter
> 200 beats per min
Bradycardia
< 60 bpm
Tachycardia
> 100 bpm
Treat sinus tachycardia by
giving oxygen
Treat sinus bradycardia by
giving oxygen and atropine
Treat atrial flutter by
giving digoxin, beta blockers, calcium channel blockers
Treat atrial fibrillation by
giving digoxin, beta blockers, calcium channel, anticoagulants, antithrombotics
Treat premature ventricular contractions and multifocal premature ventricular contractions by
giving oxygen, lidocaine, consider other causes
Treat ventricular tachycardia by
pulse present ( stable vt ) : cardiovert
pulse absent ( unstable vt ) : defibrillate, CPR, epi and amiodarone
Ventricular flutter treatment
defibrillate, CPR, epi, amiodarone
Asystole treatment
confirm in 2 leads first, CPR, epi
Ischemia
reduce blood flow to tissue
Injury
acute damage to tissue ( often from ischemia )