USMLE Step 1 Sample Test Questions Review

This set of vocabulary flashcards covers essential laboratory reference ranges, clinical diagnostic terms, and medical research concepts based on the USMLE Step 1 sample test materials.

A 27-year-old woman comes to the emergency department because of a 1-hour history of severe shortness of breath. She has just returned from a cross-country flight. She has a history of borderline hypertension. Temperature is 36.9°C (98.5°F), pulse is 113/min, respirations are 28/min, and blood pressure is 138/85 mm Hg. Oxygen saturation is 89% on room air. Lungs are clear. The right calf has an increased circumference compared with the left calf, and there is tenderness behind the right knee. Which of the following is the most likely underlying cause of this patient's condition?

(A) Antithrombin III deficiency

(B) Factor V Leiden mutation

(C) Glanzmann thrombasthenia

(D) Protein C deficiency

(E) von Willebrand disease

(B) Factor V Leiden mutation

Naphthylamine

A laboratory chemical associated with an increased risk of developing urothelial carcinoma.

Myasthenic (Lambert-Eaton) syndrome

A neuromuscular disorder often associated with bronchogenic carcinoma that causes muscle weakness and profound residual blockade after the use of pancuronium.

Finasteride

A medication used in clinical studies regarding prostate cancer; increasing the sample size of a finasteride study typically results in a lower chance of a Type II error.