Pharm Lecture #4

Drug affinity

how well a drug is able to combine with a receptor

efficacy

how effective the drug is

agonist

a drug with a high affinity, that brings about a specific action by binding with its receptor

antagonist

inhibits a specific response by binding with a specific receptor; a drug that blocks another drug from combining with a receptor

potency

the amount of a drug concentration needed to produce a desired response/effect

therapeutic index

the relationship between a drug's ability to achieve the desired effect and its tendency to produce toxic effects; ratio between toxic dose and therapeutic dose

is a lower therapeutic index safer or more dangerous?

Dangerous; Lower number = Less safe

what does it mean when a drug has a narrow therapeutic range?

its effective dose and toxic doses are close to each other

idosyncratic drug reaction

any unusual or unexpected reaction to a drug that was not listen on the drug insert

What is a generic name?

it is the more concise name that is given to a chemical compound for a drug

What is the trade name?

a name given to a drug by a manufacturer to its particular brand of drug; should have trademark logo

What is drug compounding?

the practice of diluting or combining drugs to form a new concentration or combination that is in the animals best interest; ex - flavors, routes, etc

Since drug compounding is a "new drugs" it is considered what?

Extra label drug use (EDLU)

What are neutraceuticals?

a nutrient or supplement that has demonstrated drug-like health benefits but cannot claim to have these benefits according to present regulatory policy; not FDA approved