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what does epithelium cover
Surface
largest organ in the body? what % of body weight
skin 7%
connective tissue function
provides underlying stability
what’s abundant in connective tissue
blood vessels
where is smooth muscle found
in the walls of blood vessels and attached to hairs
nervous tissues controls what and provides what
blood vessels and sensation
fucntino of integumentary 6
physical protection
Regulation of body temp
excretion (secretion)
nutrition (synthesis)
sensation
immune defense
oil glands are called
sebaceous glands
sweat glands are called
sudoriferous glands
what is the most abundant cell type
keratinocytes
function of keratinocytes
produce keratin (tough protein) that gives epidermis protection
where are keratinocytes found
arise from deepest layer of epidermis from cells undergoing mitosis
what does keratinocytes produce
(besides keratin)
anibioitecs and enzymes to detoxify the body
melanocytes function
produce melanin
Merkle cells
sensory nerve endings can serve as receptors to touch
Langerhans cells function
macrophage using receptor mediated endocytosis
5 layers of epidermis
stratum carenum
stratum lucidum
stratum granulosum
stratum spinosum
stratum basale
stratum carenum
mostly dead keratinocytes, water-proofing glycolipids, 15-30 cells thick, is keratinized
stratum lucidum
transition zone of keratin, only found in thick skin
stratum granulosum
3-5 layers of keratinocytes contains keratohyaline and lamellated granules
cytoplasm of keratinocytes contain
keratohyaline and lamellated granules
keratohyaline
helps form karatin
lamellated granules
contain water proofing glycolipids
stratum spinosum
thick bundles of pre-keratin, Langerhans cells, keratinocytes look spiky here
stratum Basale (stratum germinativum)
single row of basal cells, contains Merkel cells and melanocytes, continuous mitosis happens here
what makes keratinocytes look spiky
production of interconnection proteins called tonofibrils
tonofibrils function
increase stability
cells found in the dermis
fibroblasts, macrophages, mast cells, and scattered white blood cells
what fibers are in the dermis
gcollagen, elastic, and retiuclar
funcitno of the dermis
nourishment and tempature regulation
papilary layer
20% of dermis: loose areolar connective tissue
what structures are in the papillary layer
dermal papillae and epidermal ridges
dermal papillae function
finger like pegs which project into the epidermis and make fingerprints
reticular layer
under the papillary layer: 80% dense irregular connective tissue
what fibers are common in reticular layer
collagen fibers which extend into the layers under and above it which binds everything together
layer below reticular layer
hypodermis or subcutaneous layer
what does the reticular layer provide for the skin
strength and resilience
what structures are found in the reticular layer
blood vessels, glands, muscles, hair follicles, and nerve endings
cutaneous plexus
network of blood vessels at border of reticular layer rand hypodermis
papillary plexus
network of blood vessels just deep to the epidermis wha
what do the cutaneous plexus and papillary plexus functions
thermoregulation and overall blood flow
What form the union of a Merkel cell with a sensory nerve ending
tactile discs
what are the receptors in the skin
tactile corpuscles
root hair plexus
Ruffini Corpuscles
lamellated corpuscles
3 main factors of skin color
Thickness of stratum corneum
amount of pigment in epidermis (melanin)
blood supply in the dermis
hypodermis function
store fat, anchors skin to underlying structure (muscle), insulates us
where do most of our injections happen
hypodermis
main function of hair
sense things
minor functions of hair
protection (UV rays), trapping particles (nasal), movement (goosebumps)
where is soft keratin typically foun
in epidermal cells
hair root
part of hair attached to follicle under the skin
hair follicle
a sheath around the hair root
medulla
central core containing large cells and air spaces
3 concentric layer of keratinized hair
medulla, cortex, cuticle co
cortex
several layers of flattened cells
cuticle
single outer layer of cells, that overlap mostly heavily keratinized for strength
mammary glands
milk producing glands in breasts
ceruminous glands
modified sweat glands in external auditory canal
Cerumen
earwax formed from secretion of these glands