9.2: Intro to Glycolysis

glycolysis

10 oxidation reactions of glucose that yield two pyruvate molecules.

where

takes place in cytosol outside of mitochondria

what happens

covalent bonds between carbon and hydrogen atoms in glucose are oxidised releasing some of the stored energy

products

2x pyruvate 2x ATP 2x NADH

NADH

is an electron carrier that stores energy used in cellular respiration.

2 stages

1st half = energy-investing reactions - consumer 2 ATP per glucose

2nd half = energy-releasing reactions that produce ATP and NADH

main regulation of glycolysis

Step 3 - ATP acts as allosteric inhibitor for enzyme phosphofructokinase = too much ATP glycolysis will slow down = following steps slow down

pyruvate oxidation

pyruvate is converted into acetyl-CoA, producing NADH and carbon dioxide - links glycolysis to the Krebs cycle.