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Vocabulary flashcards covering key concepts from sensory receptors, transduction, interpretation of sensory information, receptive fields, somatic nervous system, and neuromuscular transmission.
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Receptor adaptation
Receptors become less sensitive to constant stimulation over time.
Tonic receptors
Adapt slowly or not at all; provide a constant signal during a stimulus.
Phasic receptors
Adapt quickly; respond best to changes in stimulus.
Receptor potential
Graded potential produced in a sensory receptor in response to a stimulus.
Sensory transduction
Conversion of stimulus energy into electrical energy (action potentials) in the nervous system.
Mechanoreceptors
Receptors that respond to mechanical stimuli such as touch, pressure, vibration, and proprioception.
Thermoreceptors
Receptors that detect changes in temperature (warmth and cold).
Nociceptors
Pain receptors that respond to mechanical, thermal, or chemical stimuli.
Chemoreceptors
Receptors that respond to chemical stimuli (e.g., CO2, pH).
Proprioceptors
Receptors that monitor the position and movement of joints and muscles.
Free nerve endings
Tactile receptors in the skin that respond to touch/pressure; slow adapting.
Root hair plexus
Receptor that detects movement of hair; fast adapting.
Tactile discs
Touch and pressure receptors in the epidermis; slow adapting.
Meissner’s corpuscles
Tactile receptors for light touch, pressure, and vibration; rapid adapting.
Pacinian (Lamellated) corpuscles
Deep pressure and vibration receptors; rapid adapting.
Ruffini endings
Deep sustained pressure receptors in the reticular dermis; slow adapting.
Two-point discrimination
Ability to distinguish two closely spaced points as separate stimuli.
Receptive field
Area monitored by a single sensory neuron.
Receptive field size variation
Fields are small in sensitive areas (e.g., lips) and large in less sensitive areas (e.g., back).
Primary somatosensory cortex
Cortex area where touch, pressure, and proprioceptive information is mapped.
Labelled lines
Distinct neural pathways that carry specific stimulus types to the cortex.
First-order neuron
Afferent neuron sending action potentials toward the CNS.
Second-order neuron
Neuron in the spinal cord or brainstem that relays to the thalamus or cerebellum.
Third-order neuron
Neuron from the thalamus to the cerebral cortex.
Stimulus type (labelled line concept)
The cortex identifies the type of stimulus based on the specific labelled line activated.
Stimulus intensity
Determined by the frequency of action potentials and the number of receptors activated.
Stimulus location
Determined by receptive field organization and cortical mapping of the area stimulated.
Receptive field
Area monitored by a single sensory neuron; size varies by body region.
Somatic nervous system
Division of the PNS that controls skeletal muscle.
Motor unit recruitment
Activation of more motor units to increase contraction strength.
Frequency of action potentials
Higher AP frequency increases muscle tension.
Neuromuscular junction (NMJ)
Synapse where the motor neuron communicates with a muscle fiber.
Acetylcholine (ACh)
Neurotransmitter released at the NMJ to trigger a muscle action potential.
Ca2+ in NMJ (presynaptic)
Ca2+ enters the presynaptic terminal triggering ACh release.
Ca2+ release in muscle (sarcoplasmic reticulum)
Ca2+ release into the cytosol from the SR triggers muscle contraction.
Troponin
Regulatory protein on actin that binds Ca2+ and moves tropomyosin away from myosin binding sites.
Tropomyosin
Regulatory protein that covers actin binding sites; moved by Ca2+-bound troponin.
Cross-bridge cycling
Myosin heads bind, pivot (power stroke), detach, and re-cock to pull actin.
Power stroke
Myosin head pivots to slide the thin filament toward the center of the sarcomere.
ATP in contraction
ATP provides energy for detachment and re-cocking of myosin heads.
Motor neuron action potential at NMJ
AP arrival opens voltage-gated Ca2+ channels; Ca2+ triggers ACh release.
ACh receptor-channel (nicotinic-like)
Ion channel at the motor end plate that opens to cations when ACh binds.
T tubules and SR in muscle
APs travel via T-tubules to trigger Ca2+ release from the sarcoplasmic reticulum.
Ca2+ reuptake
Ca2+ pumped back into the sarcoplasmic reticulum when APs stop, enabling relaxation.
Twitch
A single, brief muscle contraction in response to a single AP.
Tetanus (fused contraction)
A smooth, sustained contraction resulting from high-frequency stimulation.
A-delta fibers
Fast, myelinated nociceptive fibers conveying sharp pain.
C fibers
Slow, unmyelinated nociceptive fibers conveying dull, aching pain.