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How does the body obtain energy?
In chemical form, from food
How does body use energy?
Biosynthesis, maintenance, generation of external work
How is energy lost?
heat
Small animals and energy
-eat more relative to their body size
-large SA to V ratio
-high metabolism
-lose energy fast
large animals and energy
- don't eat as much
- smaller SA to V ratio
-slower metabolism
glycolosis
breaks down glucose into 2 molecules of pyruvate and 2 NET ATP
Does glycolysis require oxygen?
No, it is anaerobic
krebs cycle
-starts with pyruvic acid from glycolysis
-makes 5 ATP (most of any process)
-turns the pyruvate into acetyl coenzyme A
Does the Krebs cycle need oxygen?
yes, aerobic
Where does the Krebs cycle occur?
mitochondria
How many ATP made from glycolysis and krebs combined?
27
electron transport chain
for every 10 protons moved - 2.5 ATP made
How many protons does complex 1 move?
4 protons
How many protons does complex 2 move?
none
How many protons does complex 3 move?
4 protons
How many protons does complex 4 move?
2 protons
oxidative phosphorylation
Gradient formed by the electron transport chain acts as an energy store
- ATP synthase moves protons to "complex 5" which makes heat
-useful for hibernation
More protons in intercellular space=
=more ATP can be made
Lactic acid
-Made if only glycolysis is performed
-makes muscles hurt
-can be turned back to pyruvic acid to continue whole krebs and electron transport chain process
Sprinters vs. Marathoners
-sprinters use lots of glycogen in muscles
-marathon runner needs fatty acids
oxygen at start vs end of exercise
- at the start of exercise, lag of O2 demand before body realizes it needs to kick in
- at end of exercise, body has excess O2 until it realizes its no longer necessary
Energy storage for performing work
In order from using first to last
1. Creatine (ATP storage) for energy
2. ATP from glycolosis (anerobic)
3. ATP from Krebs cycle (aerobic)
4. ATP from fat
Things required for egg and sperm to meet
- environmental cues
-developed reproductive organs
-acquisition of resources
-attraction of mates
-copulation (intercourse)
Things required for successful offspring
-development of zygote
-provisioning of offspring
-evasion of predators
-parental time
-no environment stress
mammal sex determination
XX- female
XY- male
50/50 shot
males determine the sex
Birds and reptiles sex determination
use Z and W
50/50 shot
mom determines sex
turtle sex determination
temperature
hot=female
cold=male
A lot of lizards are only females in the species
True, they can clone themselves
Ant sex determination
fertilized egg= female
non fertilized egg= male (have no father)
called a haploid-diploid system
Reproduction up North (in poles)
Peak of reproduction is at spring
-so they are mature by fall when the cold weather becomes harsh
reproduction in tropics
Can effectively reproduce at anytime
dipause
A pause in development for them to catch up on weather
Examples of dipause
-silkworms have dipause in winter within their eggs to hatch in the spring
-antartic fur seals have dipause right after birth in summer/fall
male and females have same external genitalia for a while in the womb
True, males change right before birth
female reproductive system
2 ovaries- connected to oviducts- leads to uterus- cervix- then vagina
Where doe sperm interact in females
in oviduct, then embryo attaches to the uterus
corpus luteum
secretes hormones for early pregnancy (progesterone)
How does the female cycle work?
-Follicles mature from primary to secondary, then oocyte gets released (ovulation)
- the area around it forms a mature Corpus leuteum
-if not fertilized, the CL will stop secreting and move away
-This causes the uterine lining to shed since no pregnancy occured
FSH (follicle stimulating hormone)
stimulates follicular phase
LH (luteinizing hormone)
surge triggers ovulation
-can test LH levels to see when you will ovulate
Progesterone
helps support pregnancy
-secreted by CL
Estrogen
stimulates development of follicles
Inhibin
inhibits secretion of FSH (inhibits follicular phase)
-causes follicles to rupture for ovulation
why does the uterine lining shed?
Lots of blood vessels are formed in uterus in case there is an embryo to provide nutrients for after ovulation (secretory phase)
-so it sheds if nothing attaches
-called menstral phase
proliferate phase
-right after menstral phase
-corelates to follicles devolping
-has high estrogen and low progesterone
HPG axis
controls reproductive system
How is estrogen secreted?
-hypothalamus secretes GnRH
-anterior pituitary secretes LH and FASH
-LH stimulates Theca cells (outer most part of follicle) to produce androgens
-androgens move inside to granulosa cells (second layer of follicle)
-aromatase (enzyme) turns androgens into estrogen
-estrogen is secreted into blood and helps follicle mature
How is the LH surge triggered?
Cervix sends info to make GnRH
-GrNH produces the LH surge at copulation
male reproductive system
testi- vas derens- semical vesicle- prostate glans-penis
testis
produces sperm
semical vesicle and prostate gland
-produce semen
-gives nutrients to sperm to survive
Scrotum
makes sure sperm doesn't overheat
Leydig cells
produce testosterone in seminiferous tubule
parts of sperm
-head is called acrosome- helps penetrate oocyte
-has mitochondria in the middle to help tail swim
-tail
Testosterone
-surge before birth if embryo is male
-surge after birth for final touches
-in low phase from ages 1-10ish when testes drop
-spikes at puberty which beings sperm production
-stays high forever on
teste size
-smaller testes tend to mate for life with single female
-multi-male mating= larger testes (bc more surface area for more testosterone to make more sperm and offspring)
fertiliation steps
1. oocyte is in oviduct as sperm arrives
2. sperm head binds to specific receptors on zona pellucida (outside of oocyte)
3. sperm interacts with oocyte body which doesn't let any other sperm in
4. sperm releases its contents into oocyte cytoplasm aka DNA
*space between zona pellucida and oocyte is call perivitelline space
when is spike of hCG
after fertilization
-only seen if uterus attaches
CL then produces high levels of progesterone and estrogen during pregnancy after hCG spike
when do estrogen, progesterone, and hCG all drop?
after birth
-this can lead to lack of care from the mother
How does a woman's body give birth?
-cervix and uterus get stretched before birth which sends signals to the hypothalamus
-The hypothalamus tells posterior pituitary to release oxytocin into blood
-oxytocin tells uterus to contract
-also produces prostaglandins which help uterus contract
- a positive feedback loop keeps calling for more oxytocin
marsupials
-have 3 vaginas
-can keep one baby in uterus and another in pouch
-can pause pregancy
-ex: kangaroos
Monotremes
mammals that lay eggs (platypus)
-1 hole for everything
-lay eggs, but still use milk from mom's body
placental mammals
-nourish their young with milk from nipples and placenta
Mom's energy needs to be highest at
weaning (transition from milk to food)
- this is because baby's body is smaller earlier on so less energy/milk is needed until it is big enough to have real food
Milk production: suckling activates...
CNS which allows for lower dopamine and higher TRH hormones
-this causes prolactin to secrete from anterior pit. and oxytocin from posterior pit.
prolactin
allows epithelial cells to make milk
oxytocin
allows the milk to be ejected
ionotropic transduction
ions go through channels to activate signal
Metabotrophic transduction
ligate binds to receptor for signals
Mechanoreceptors
respond to touch, pressure, vibration, stretch, and itch
ionotropic
vestibular receptors
balance, body position and movement; ionotropic
Osmoreceptors
osmotic pressure
ionotropic
auditory recpetors
sound
ionotropic
Thermoreceptors
heating and cooling
ionotropic
Electroreceptors
detect electrical fields
ionotropic
salty and sour taste chemorecptors
ionotropic
sweet, bitter, umami
metabotropic
olfacotry receptors
smell
chemicals from a distance
metabotropic
Photoreceptors
light
metabotropic
Magnetoreceptors
detect magnetic fields
unknown transduction
sensory recepetors
- go from sensors to CNS without interacting with each other to make signals as fast as possible
-each corralates with a part of the brain
- when the sensors detect above a threshold, the body realizes a change in environment
-frequency and strength of the signal matters
free nerve ending
paint, itch, temp
merkel disc
touch and pressure
meissner corpuscle
touch
Ruffini endings
pressure
Pacinian corpuscles
vibration
tonic receptors
-merkel disc and ruffini ending
-impulses continue during long stimulus
phasic receptors
-meissner corpuscle
- impulses happen in change of level of intensity
Extremely phasic receptor
-pacinian corpuscle
- neglible signal outputs
Taste depends on
smell
each part of tongue tastes a different flavor
FALSE all parts of tongue can detect all 5 tastes
ear
converts sound energy to neural signals, then brain processes the info
cochlea
-filled with saltwater fluids
-inner ear
-frequencies detected on all different parts of cochlea
eardrum and middle ear
convert movement of eardrum to pressure waves in cochlea fluid
basliar membrane
has hairs on outside of cochlea that translates frequencies to nerves
high vs low frequency
-high frequency sounds=more intense and happen over shorter distance
-low frequency sounds= stretched out over longer distance and reach ear first
Pathway of sound through the ear
pinna-> ear canal-> eardrum-> tympanic membrane> malleus, incus, and stapes> cochlea-> hair cells (basial membrane) -> brain
range for animal hearing
14- 200,000
but each has its own specific range
ex: bats hear highest frequency at 7,000-200,000
ex: elephants hear lowest range at 14-12,000
Tympanal organs
hearing organ in insects
-membrane with air sacs and sensory nerves
first sense you are born with
smell