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Amyloidosis (accumulation of protein in the spleen)
Spleen is organ most involved
Amyloidosis NODULAR
amyloid found in wall of arteries and follicles
not in red pulp
Amyloidosis DIFFUSE
red pulp involved
follicles not involved
Gaucher’s Disease
rare familial disorder
50% under age 8
What disease is this?
Gauchers
Gaucher’s Disease US
splenomegaly
diffuse inhomogeneity
MULTIPLE HYPOECHOIC SPLENIC NODULES
Niemann-Pick Disease
Rapidly progressing fatal disease
female infants (jewish)
Niemann-pick disease US
Splenomegaly
hepatomegaly
digestive disturbances
lymphadenopathy