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Vocabulary flashcards covering the cells of the nervous system, neuron structure, glial cells, membrane biology, and basic protein synthesis.
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Golgi method (Golgi staining)
Silver staining technique that reveals individual neurons in tissue, supporting the neuron doctrine.
Neuron doctrine
Idea that neurons are discrete units that transmit signals, not a continuous nerve net.
Brainbow
Modern method using fluorescent proteins to visualize individual neurons and trace their connections.
Neuron
The basic functional cell of the nervous system that transmits information.
Glia
Non-neuronal cells that support, nourish, insulate, and repair neurons; outnumber neurons.
Astrocyte
Star-shaped glial cell that nourishes neurons, helps form the blood-brain barrier, and interacts with blood vessels.
Microglial cell
Glial cell that acts in CNS defense and debris cleanup; small and derived from blood.
Oligodendroglial cell (oligodendrocyte)
Glial cells in the CNS that form myelin around axons.
Schwann cell
Glial cells in the peripheral nervous system that form myelin around peripheral nerves.
Ependymal cell
Glial cell that moves cerebrospinal fluid.
Blood-brain barrier
Barrier formed by tight junctions in brain vessels; astrocyte end feet help regulate nutrient entry.
Membrane
Phospholipid bilayer that encloses the cell, separating intracellular from extracellular fluids.
Nucleus
Structure containing chromosomes and genetic material.
Mitochondrion
Organelle that provides energy for the cell.
Ribosomes
Sites where proteins are synthesized.
Endoplasmic reticulum
Membrane network where proteins are assembled and transported.
Golgi body
Organelle that packages proteins for transport to their destinations.
Lysosomes
Vesicles containing enzymes that digest waste material.
Dendrite
Neuron extension that collects information from other cells.
Dendritic spine
Small protrusion on a dendrite that increases surface area for synapses.
Soma (cell body)
The core region of a neuron containing the nucleus and cytoplasm.
Axon
Extension that transmits information from the cell body to other neurons.
Axon hillock
Junction of soma and axon where the action potential begins.
Axon collaterals
Branches of an axon.
Terminal button
Knob at the tip of an axon that conveys information to other neurons; also called end foot.
Synapse
Gap between two neurons where communication occurs.
Presynaptic terminal
End point of an axon where neurotransmitters are released.
Postsynaptic neuron
Neuron that receives chemical transmission from a nearby neuron.
Nodes of Ranvier
Gaps in the myelin sheath along an axon that facilitate rapid signal conduction.
Myelin sheath
Glial insulation around axons that speeds transmission; produced by Schwann cells in the PNS and oligodendrocytes in the CNS.
Sensory neuron (afferent)
Neuron that carries information from sensory receptors to the CNS.
Interneuron
Association neuron that connects neurons within the CNS.
Motor neuron (efferent)
Neuron that sends signals from the CNS to muscles.
Channel
Opening in a membrane protein that allows ion passage.
Gate
Membrane protein that opens or closes to regulate passage.
Pump
Membrane protein that actively transports substances across the membrane.
Phospholipid bilayer
Two-layer cell membrane with hydrophilic heads facing water and hydrophobic tails inward.
Hydrophilic heads
Water-attracting parts of phospholipids facing the aqueous environment.
Semipermeable
Membrane property that allows some substances to pass while blocking others.
Chromosome
Double-stranded DNA molecule that carries genetic information.
DNA
Deoxyribonucleic acid; molecule encoding genetic information.
Transcription
Process of copying a gene’s DNA sequence into mRNA.
mRNA
Messenger RNA that carries genetic information from DNA to ribosomes.
Translation
Process by which ribosomes read mRNA and assemble amino acids into a protein.
Amino acid
Building blocks of proteins.
Polypeptide chain
A chain of amino acids that folds into a protein.
Protein
Molecule that performs a wide range of cellular functions; determined by amino acid sequence and folding.
Protein folding
Process by which a protein attains its functional three-dimensional shape.