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Neurons-
Plan/ execute behavioral responses, learn new info, attend to a stimulus, speaking, eating, mating, & guaging threats.
Santiago Ramón y Cajal concluded that individual neurons are-
Structural & functional; distinguishable processing units, not continuous structure
The Electrochemical Process is how nuerons-
communicate through electrochemical signals.
Resting Membrane Potential:
The voltage inside the cell relative to the voltage outside the cell while the cell is a rest (approximately -70 mV).
A resting cell has what distribution of energy (relative to intracellular and extracellular)?
Positive energy outside; negative energy inside
Dendrites:
Part of a neuron that extends away from the cell body and is the main input to the neuron.
Nucleus:
Located inside some and contains genetic info, directs protein synthesis, and supplies energy/resources neuron needs to function.
Axon:
Main source of output (acts on- like axon); extends from soma and carries signal called action potential.
What part of the neuron is covered with an insulating substance called myelin sheath?
The axon
Myelin sheath:
Substance around the axon of a neuron that serves as insulation to allow the action potential to conduct rapidly toward the terminal buttons.
Terminal Button:
The part of the end of the axon that form synapses with postsynaptic dendrite, axon, or soma.
Synthetic Gap
Also known as the synaptic cleft; the small space between the presynaptic terminal button and the postsynaptic dendritic spine, axon, or soma.
Synaptic vesicles:
Groups of neurotransmitters packaged together and located within the terminal button.
Neurotransmitters are released from where?
Released by the presynaptic terminal button that acts on the postsynaptic cell.
Sensory Nuerons:
Help us receive info about the world around us
Motor Neurons:
Facilitate movement and behavior
Interneurons:
Process sensory input from environment, plan response, and bind to motor neurons to execute plans.
The three categories of neurons are:
Unipolar neurons, bipolar neurons, and multipolar neurons
Unipolar neuron:
Used to relay info forward- transmit vital physical information like pain, touch, temperature, and pressure; has one neurite and no dendrites.
Bipolar neuron:
Specialized version of unipolar neuron- involved in sensory/ perception (like perception of light) and help pass that info to various parts of the brain; have one axon and one dendrite
Multipolar neuron:
Most common, in charge of communicating with other neurons (pyramidal neuron), and are drivers of cognition, learning, memory, and voluntary movement.
Type of gila cell that forms myelin sheath:
Oligodendroglia
What two gila cells re in charge of digesting debris of dead neurons, carry nutritional support to neurons, and regulate ionic composition of the extracellular fluid?
Microgila & astrocytes
What are the two stages of electrochemical action?
The first stage is the electrical conduction of dendritic input to the initiation of an action potential within a neuron. The second stage is a chemical transmission across the synaptic gap between the presynaptic neuron and the postsynaptic neuron of the synapse.
Intracellular and extracellular fluid are both composed of-
A combination of ions: cations (+) and anions (-).
Ion channels are made from-
proteins that span the membrane and allow particular ions to pass between the intracellular & extracellular fluid.
Diffusion:
the force on molecules to move from areas of high concentration to areas of low concentration.
Electrostatic pressure:
the force on two ions with similar charge to repel each other; the force of two ions with opposite charge to attract to one another.
Equilibrium potential is where the potential at which the force of diffusion is-
equal and opposite to the force of electrostatic pressure; no ions flow
Anions (where are they located, what is there charge, and relationship to membrane):
highly concentrated inside the cell and contribute to negative charge of resulting membrane potential; impearable to membrane so unaffected by diffusion and electrostatic pressure (nowhere to move between)
Potassium: (where are they located, what is there charge, and relationship to membrane):
highly concentrated in the cell and contributes to positive charge of resulting membrane potential; very permeable to membrane and diffusion pushes (K+) outside of cell (attracted to negative charge outside cell)
Chloride (where are they located, what is there charge, and relationship to membrane):
highly concentrated outside of cell and contributes to negative charge of resulting membrane potential; very permeable to membrane and electrostatic pressure pushes (Cl) outside the cell (attraction to (+) outside), while diffusion pushes (Cl) inside the cell (high concentration)
Sodium (where are they located, what is there charge, and relationship to membrane):
highly concentrated outside the cell and contribute to positive charge of resulting membrane potential; not very permeable to membrane so unaffected by diffusion and electrostatic pressure (nowhere to move between)
Sodium-potassium pump:
An ion channel that uses the neuron’s energy (adenosine triphosphate, ATP) to pump three Na+ ions outside the cell in exchange for bringing two K+ ions inside the cell.
Action potential:
A transient all-or-nothing electrical current that is conducted down the axon when the membrane potential reaches the threshold of excitation.
The “all or nothing response” relates to-
a cell’s action potential, which occurs when these is a change in charge of potential from resting membrane potential to a positive direction (depolarization)
Depolarization:
is a shift in a cell's electrical charge that makes the inside of the cell less negative or more positive
Threshold of excitation:
the specific membrane potential that a neuron must reach to initiate action potential
Excitatory postsynaptic potentials:
A depolarizing postsynaptic current that causes the membrane potential to become more positive and move towards the threshold of excitation.
Inhibitory postsynaptic potentials:
A hyperpolarizing postsynaptic current that causes the membrane potential to become more negative and move away from the threshold of excitation.
Two small EPSPs ate the same time will result in-
A large EPSP
At each moment each cell is recieving-
mixed messages (both EPSP and IPSP)
If the summation of EPSPs is strong enough to depolarize membrane potential to reach threshold of excitation it initiates-
Action potential
Ionotropic receptor:
Ion channel that opens to allow ions to permeate the cell membrane under specific conditions, such as the presence of a neurotransmitter or a specific membrane potential.
Depolarization:
a process where a cell's inside becomes less negative or more positive compared to its outside
A refractory period in a neuron is-
a brief time after an action potential (nerve impulse) when the cell cannot fire or needs a stronger stimulus to fire again.
Myelin insulates the axon and does not allow-
any fluid to exist between myelin and the cell membrane
Love is a biological process that is-
Dynamic and bidirectional
Evolutionary principles and ancient hormonal/neural systems support-
healing effects of loving relationships.
Molecular mechanisms favoring high levels of sociality evolve-
faster
Love is more complex than-
simple feedback mechanisms.
The modern cortex struggles to interpret love’s primal messaging and creates a narrative from-
visceral experience (gut feeling)
Oxytocin adopts a role in-
reproduction, expels baby from uterus, ejects milk, and creates bond between baby and mama.
Oxytocin can facilitate behaviors such as-
social behaviors, eye contact, and social cognition.
Oxytocin is released in response to a-
stressful experience