The Functions of the skin are these, describe what they each do:
Protection
Excretion
Thermoregulation
Sensation
Vitamin D synthesis
Epidermis (epi-on top, dermis-skin)
Keratinized stratified epithelium
Dermis
Loose connective tissue and dense irregular tissue
Hypodermis (hypo-below)
KNOWN as the subcutaneous tissue
Loose connective tissue
Anchors skin to the muscle
The Epidermis has cells called keratinocytes which are:
Keratinocytes:
Makes up 95% of the cells in the Epidermis
Strengthens the EPI + makes it resistant to mechanical trauma
Joined by desmosomes
Arranged into “strata (layers)”
Name the layers of the epidermis—> Hint: CLGSBD
Stratum Corneum
Stratum Lucidum
Stratum Granulosum
Stratum Spinosum
Stratum Basale
Presenting the 1st layer of the Epidermis STRATUM CORNEUM
Presenting the layer underneath the corneum of the Epidermis—> Stratum Lucidum
Deep to the Stratum Corneum
Found in THICC skin
Clear layer of dead Keratinocytes
Presenting the layer underneath the Lucidum of the Epidermis—> Stratum Granulosum
Middle layer of the epidermis
Named for prominent granules
3-5 rows of cells
Excretes a lipid-based substance
Presenting the layer underneath the Granulosum of the Epidermis—>Stratum Spinosum
Thiccccest stratum
Undergo mitosis
Help to synthesize vitamin D
Presenting the layer underneath the Spinosum of the Epidermis—> Stratum Basale
Consists of a single layer of stem cells
Undergo mitosis
Known as (Stratum Germinativum)
Helps to synthesize vitamin D
Keratinocyte Life Cycle
Begins in the Strum Spinosum
Sheds in the Stratum Corneum
Other cells of the epidermis:
Dendric Cells
Merkel Cells
Melanocytes
Dendric Cells
-Protects the skin and underlying tissue from pathogens (found in Stratum Spinosum)
Merkel Cells
-Oval cells found in the Stratum Basale (found in Stratum Basale)
Melanocytes
Produces melanin, a protein (found in stratum Basale)
Thick Skin Vs Thin skin
THICK SKIN
Consists of all five layers of the epidermis with a thick Stratum Corneum
Lacks hair follicles+ contains sweat glands
Found in palms of hand and soles of feet
Subject to mechanical stress
Thick Skin Vs Thin skin
Thin skin
Consist of only four layers of the epidermis, lacking the Stratum Lucidum
Has hair follicles
Subject to less mechanical stress
The Dermis Layer
Dermis has Two Layer:
-PALPILLARY LAYER
-RECTICULAR LAYER
House blood supply
Papillary Layer (dermis layer)
Loose connective tissue
we can find phagocytes and fibroblast
Superficial layer of the dermis
Dermis Papillae:
Found on the surface of the papillary layer
Houses tiny blood vessels called capillaries
houses sensory receptors called Tactile corpuscles
Reticular Layer (Under Papillary layer)
Deepest and thickets layer of the dermis
Consist of dense irregular connective tissue
Collagen fibers that allow skin to revert after stretching
Proteoglycans that hydrate the skin
Blood vessels and accessory structure (hair, sweat glands, sebaceous glands)
Sensory receptors, such as Pacinian corpuscles that respond to changes in pressure and vibration ( 14:50)