Comparative Proteomics

Proteomics

the study of sets of proteins and their properties

How many types of muscles are there in the muscular system?

Three

What are the different types of muscles?

skeletal, smooth, cardiac

What is a muscle cell?

muscle fiber

The order of connective tissue wrappings of skeletal muscle

Muscle Fiber, Endomysium, Fascicle, Perimysium, Epimysium

Endomysium

connective tissue that wraps around the cell

Fascicle

a bunch of muscle fibers

Perimysium

a connective tissue wraps around a fascicle

Epimysium

connective tissue that wraps the whole thing

Sarcolema

a cell membrane that is referred to as a fiber

Nuclei

Many and oval shaped

Myofibril

Cylindrical structures that is wrapped by the sarcoplasmic reticulum

Sarcoplasmic Reticulum

surrounds myofibrils and stores and releases calcium for muscle contraction

Myofilaments

actin and myosin

Actin

thin filaments

Myosin

thick filaments

Sarcomere

functional unit of contraction

where does sarcomere start at

z-disc

where does sarcomere end at

z-disc

what is in the middle of the sarcomere

h-zone

a band (dark band)

contains myosin and actin filaments

i band (light band)

contains actin filaments

how a muscle contracts

1) the sarcoplasmic reticulum releases calcium.

2) calcium binds to actin, exposing binding sites

3) myosin binds to actin, pulling the actin inward

4) the sarcomere shortens, leading to muscle contraction

Skeletal Muscle

voluntary, multinucleated

Smooth muscle

involuntary, in organs

Cardiac muscle

heart, striated, involuntary

Sarcomere

Contractile unit of muscle

sarcoplasmic reticulum

stores calcium