skeletal muscle action, respiratory movement, and contraction of smooth muscle in vessel walls.
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Functions of the Lymphatic System
1\. Transports proteins and fluids, lost by capillary seepage, back to the bloodstream.
2\. Participates in the body’s immune response.
3\. Is the pathway for the absorption of fats from the small intestine into the bloodstream.
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Lymph
is clear, nearly colorless, alkaline fluid that occupies the space between all cells of the body.
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interstitial fluid
Lymph is termed _____ and is similar to blood plasma
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95%, capillaries
Composed of __ water. It seeps in and out through the walls of very small vessels called _____
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Functions of Lymph Nodes
filters, slows down, and cleans the lymph before returning it to the blood.
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Lymph Nodes
Dark lumps on the membrane that trap and sometimes become swollen with bacteria that has invaded the body AND the white blood cells that fight that bacteria.
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TRUE
The lymphatic system plays an important role in the development or spread of cancer.
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Lymphoma
Cancer that starts in the lymph nodes is called ***____.***
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Metastatic Cancer
When cancer cells break off a tumor and spread into the lymph nodes, it is known as ***_______.***
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Sentinel Node
Nearest node where the dye is injected
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Spleen
is a soft, dark purple organ found in the upper-left portion of the abdomen and surrounded by blood and lymph vessels.
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Red Pulp
The _____ of the spleen removes old red blood cells (erythrocytes) from the blood supply.
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White Pulp
The ______ of the spleen removes, stores and produces white blood cells (lymphocytes).
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Splenectomy
Surgical Removal of Spleen
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Liver
Once the spleen is removed, majority of its functions are taken over by the _____
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11-12cm or 4 1/2 inches
Normal length of spleen
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Tonsils
Located in masses of tissue in the back of the throat, they filter bacteria and produce white blood cells.
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Tonsillectomy
Tonsils are sometimes removed if they become so large, they cause an obstruction or if they are chronically inflamed. Removal of Tonsils is called _____
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Thymus
It manufactures one specific type of the infection-fighting lymphocytes called T-cells.
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False
The thymus gland is not considered as part of the endocrine system but is actually part of the lymphatic system due to its appearance and function.
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Lymphocytes
The lymph nodes and spleen and thymus hold special WBC called ____
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Lymphocytes
Can rapidly multiply and release antibodies in response to bacteria, viruses, and a range of other stimuli from dead or dying cells and abnormally behaving cells, like cancer
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Granulocytes
Eosinophils, Basophils, Neutrophils
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Two main types of Lymphocytes
B cells and T cells
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B Cells
Produce Antibodies used to attack invading bacteria, viruses, and toxins
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T Cell
Destroy the body’s own cells that have themselves taken over by viruses
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Body Defenses
Nonspecific Defense System and Specific Defense System
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Nonspecific Defense System
* Mechanisms protect against a variety of invaders * Responds immediately to protect body from foreign materials
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Specific Defense System
* Specific defense is required for each type of \n invader * Also known as the immune system
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First Line of Defense
Surface Membranes, Stomach Mucosa, Body Openings/Secretions
* _____ to inhibit bacterial growth * ______ is toxic to bacteria
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Stomach mucosa
* Secretes hydrochloric acid * Has protein-digesting enzymes
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Body openings/ secretions
* Saliva and lacrimal fluid contain lysozyme * Vaginal secretions are very acidic * Mucus traps microorganisms
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Defensive Cells
Phagocytes and Natural Killer Cells
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Phagocytes
* (neutrophils macrophages) * Engulfs foreign material into a vacuole * Enzymes from lysosomes digest the material
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Natural killer cells
\ * Can lyse and kill cancer cells * Can destroy virus- infected cells
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Inflammatory Response
Triggered when body tissues are injured, Results in a chain of events leading to protection and healing,
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Functions of Inflammatory Response
* Prevents spread of damaging agents * Disposes of cell debris and pathogens * Sets the stage for repair
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Cardinal Signs of Inflammatory Response
* Redness * Heat * Swelling * Pain
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Complement
* A group of at least 20 plasma proteins * Activated when they encounter and attach to cells (complement fixation) * Damage foreign cell surfaces * Has vasodilators, chemotaxis, and opsonization
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Interferon
* Secreted proteins of virus-infected cells * Bind to healthy cell surfaces to inhibit viruses binding.
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Fever
* Abnormally high body temperature * Hypothalamus heat regulation can be reset by \n pyrogens (secreted by white blood cells) * High temperatures inhibit the release of iron and zinc from liver and spleen needed by bacteria * Fever also increases the speed of tissue repair