Biochem Amino Acids

Alanine — give the 3-letter code, 1-letter code, and category.

Ala; A; nonpolar/hydrophobic.

Ala — what amino acid, 1-letter code, and category?

Alanine; A; nonpolar/hydrophobic.

A — what amino acid, 3-letter code, and category?

Alanine; Ala; nonpolar/hydrophobic.

Arginine — give the 3-letter code, 1-letter code, category, and R-group pKa.

Arg; R; positively charged; pKa = 12.5.

Arg — what amino acid, 1-letter code, category, and R-group pKa?

Arginine; R; positively charged; pKa = 12.5.

R — what amino acid, 3-letter code, category, and R-group pKa?

Arginine; Arg; positively charged; pKa = 12.5.

Asparagine — give the 3-letter code, 1-letter code, and category.

Asn; N; polar uncharged.

Asn — what amino acid, 1-letter code, and category?

Asparagine; N; polar uncharged.

N — what amino acid, 3-letter code, and category?

Asparagine; Asn; polar uncharged.

Aspartate/Aspartic acid — give the 3-letter code, 1-letter code, category, and R-group pKa.

Asp; D; negatively charged; pKa = 3.9.

Asp — what amino acid, 1-letter code, category, and R-group pKa?

Aspartate/Aspartic acid; D; negatively charged; pKa = 3.9.

D — what amino acid, 3-letter code, category, and R-group pKa?

Aspartate/Aspartic acid; Asp; negatively charged; pKa = 3.9.

Cysteine — give the 3-letter code, 1-letter code, category, and R-group pKa.

Cys; C; polar uncharged; pKa = 8.3.

Cys — what amino acid, 1-letter code, category, and R-group pKa?

Cysteine; C; polar uncharged; pKa = 8.3.

C — what amino acid, 3-letter code, category, and R-group pKa?

Cysteine; Cys; polar uncharged; pKa = 8.3.

Glutamate/Glutamic acid — give the 3-letter code, 1-letter code, category, and R-group pKa.

Glu; E; negatively charged; pKa = 4.3.

Glu — what amino acid, 1-letter code, category, and R-group pKa?

Glutamate/Glutamic acid; E; negatively charged; pKa = 4.3.

E — what amino acid, 3-letter code, category, and R-group pKa?

Glutamate/Glutamic acid; Glu; negatively charged; pKa = 4.3.

Glutamine — give the 3-letter code, 1-letter code, and category.

Gln; Q; polar uncharged.

Gln — what amino acid, 1-letter code, and category?

Glutamine; Q; polar uncharged.

Q — what amino acid, 3-letter code, and category?

Glutamine; Gln; polar uncharged.

Glycine — give the 3-letter code, 1-letter code, and category.

Gly; G; nonpolar/hydrophobic.

Gly — what amino acid, 1-letter code, and category?

Glycine; G; nonpolar/hydrophobic.

G — what amino acid, 3-letter code, and category?

Glycine; Gly; nonpolar/hydrophobic.

Histidine — give the 3-letter code, 1-letter code, category, and R-group pKa.

His; H; unique amino acid; pKa = 6.0.

His — what amino acid, 1-letter code, category, and R-group pKa?

Histidine; H; unique amino acid; pKa = 6.0.

H — what amino acid, 3-letter code, category, and R-group pKa?

Histidine; His; unique amino acid; pKa = 6.0.

Isoleucine — give the 3-letter code, 1-letter code, and category.

Ile; I; nonpolar/hydrophobic.

Ile — what amino acid, 1-letter code, and category?

Isoleucine; I; nonpolar/hydrophobic.

I — what amino acid, 3-letter code, and category?

Isoleucine; Ile; nonpolar/hydrophobic.

Leucine — give the 3-letter code, 1-letter code, and category.

Leu; L; nonpolar/hydrophobic.

Leu — what amino acid, 1-letter code, and category?

Leucine; L; nonpolar/hydrophobic.

L — what amino acid, 3-letter code, and category?

Leucine; Leu; nonpolar/hydrophobic.

Lysine — give the 3-letter code, 1-letter code, category, and R-group pKa.

Lys; K; positively charged; pKa = 10.5.

Lys — what amino acid, 1-letter code, category, and R-group pKa?

Lysine; K; positively charged; pKa = 10.5.

K — what amino acid, 3-letter code, category, and R-group pKa?

Lysine; Lys; positively charged; pKa = 10.5.

Methionine — give the 3-letter code, 1-letter code, and category.

Met; M; nonpolar/hydrophobic.

Met — what amino acid, 1-letter code, and category?

Methionine; M; nonpolar/hydrophobic.

M — what amino acid, 3-letter code, and category?

Methionine; Met; nonpolar/hydrophobic.

Phenylalanine — give the 3-letter code, 1-letter code, and category.

Phe; F; nonpolar/hydrophobic.

Phe — what amino acid, 1-letter code, and category?

Phenylalanine; F; nonpolar/hydrophobic.

F — what amino acid, 3-letter code, and category?

Phenylalanine; Phe; nonpolar/hydrophobic.

Proline — give the 3-letter code, 1-letter code, and category.

Pro; P; nonpolar/hydrophobic.

Pro — what amino acid, 1-letter code, and category?

Proline; P; nonpolar/hydrophobic.

P — what amino acid, 3-letter code, and category?

Proline; Pro; nonpolar/hydrophobic.

Serine — give the 3-letter code, 1-letter code, and category.

Ser; S; polar uncharged.

Ser — what amino acid, 1-letter code, and category?

Serine; S; polar uncharged.

S — what amino acid, 3-letter code, and category?

Serine; Ser; polar uncharged.

Threonine — give the 3-letter code, 1-letter code, and category.

Thr; T; polar uncharged.

Thr — what amino acid, 1-letter code, and category?

Threonine; T; polar uncharged.

T — what amino acid, 3-letter code, and category?

Threonine; Thr; polar uncharged.

Tryptophan — give the 3-letter code, 1-letter code, and category.

Trp; W; nonpolar/hydrophobic.

Trp — what amino acid, 1-letter code, and category?

Tryptophan; W; nonpolar/hydrophobic.

W — what amino acid, 3-letter code, and category?

Tryptophan; Trp; nonpolar/hydrophobic.

Tyrosine — give the 3-letter code, 1-letter code, category, and R-group pKa.

Tyr; Y; polar uncharged; pKa = 10.1.

Tyr — what amino acid, 1-letter code, category, and R-group pKa?

Tyrosine; Y; polar uncharged; pKa = 10.1.

Y — what amino acid, 3-letter code, category, and R-group pKa?

Tyrosine; Tyr; polar uncharged; pKa = 10.1.

Valine — give the 3-letter code, 1-letter code, and category.

Val; V; nonpolar/hydrophobic.

Val — what amino acid, 1-letter code, and category?

Valine; V; nonpolar/hydrophobic.

V — what amino acid, 3-letter code, and category?

Valine; Val; nonpolar/hydrophobic.

Name all 9 nonpolar/hydrophobic amino acids.

Glycine, Alanine, Proline, Valine, Leucine, Isoleucine, Methionine, Phenylalanine, Tryptophan.

Give the codes for all 9 nonpolar amino acids.

Gly G; Ala A; Pro P; Val V; Leu L; Ile I; Met M; Phe F; Trp W.

Name all 6 polar uncharged amino acids.

Serine, Threonine, Cysteine, Tyrosine, Asparagine, Glutamine.

Give the codes for all 6 polar uncharged amino acids.

Ser S; Thr T; Cys C; Tyr Y; Asn N; Gln Q.

Name the 2 negatively charged amino acids.

Aspartate (Asp, D) and Glutamate (Glu, E).

Name the 2 positively charged amino acids.

Lysine (Lys, K) and Arginine (Arg, R).

Which amino acid is the unique classification in these lecture slides?

Histidine (His, H).

How many amino acids are classified as nonpolar?

9.

How many amino acids are classified as polar uncharged?

6.

How many amino acids are negatively charged at neutral pH?

2.

How many amino acids are positively charged at neutral pH?

2.

Which 7 amino acids have ionizable R-groups that you must know?

Aspartate, Glutamate, Histidine, Cysteine, Tyrosine, Lysine, Arginine.

What is the R-group pKa of Aspartate (Asp, D)?

3.9.

What is the R-group pKa of Glutamate (Glu, E)?

4.3.

What is the R-group pKa of Histidine (His, H)?

6.0.

What is the R-group pKa of Cysteine (Cys, C)?

8.3.

What is the R-group pKa of Tyrosine (Tyr, Y)?

10.1.

What is the R-group pKa of Lysine (Lys, K)?

10.5.

What is the R-group pKa of Arginine (Arg, R)?

12.5.