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what two hormones come from the stomach?
gastrin and gastric somatostatin
what is the source of gastrin?
stomach
what is the target area of gastrin?
stomach
what is the target area of gastric somatostatin?
stomach
what is the action of gastrin?
stimulates gastric secretory activity, increases gastric motility (movement)
what is the action of gastric somatostatin?
inhibits gastric secretory activity, stimulates insulin release
what four hormones do the small intestine produce?
Cholecystokinin (CCK), Intestinal Gastrin, Intestinal Somatostatin, and Secretin
what is the source of Cholecystokinin (CCK)?
Small Intestine
what is the source of Intestinal Gastrin?
Small Intestine
what is the source of Intestinal Somatostatin?
Small Intestine
what is the source of Secretin?
Small Intestine
what are the targets of Cholecystokinin (CCK)?
stomach, pancreas, and gall bladder
what is the target of Intestinal Gastrin?
Stomach
what is the target of Intestinal Somatostatin?
Stomach
what is the target of Secretin?
Pancreas
what is the action of Cholecystokinin (CCK) in the stomach?
Inhibits gastric secretory activity
what is the action of cholecystokinin (CCK) in the pancreas?
stimulates enzyme release
what is the action of cholecystokinin (CCK) in the gall bladder?
stimulates bile release
what is the action of Intestinal Gastrin?
Stimulates gastric secretory activity
what is the action of Intestinal Somatostatin?
Inhibits gastric secretory activity
what is the action of secretin?
stimulates bicarbonate release
what enzyme does saliva produce?
salivary amylase
what is the source for salivary amylase?
saliva
what is a substrate?
a molecule acted upon by an enzyme
what are the substrates of salivary amylase?
starch and glycogen
what is the product of salivary amylase after its substrates?
Disaccharides (Sucrose, Lactose, and Maltose)
what two enzymes does the stomach produce?
Pepsin and gastric lipase
what is the source of pepsin?
stomach - released in inactive form
what is the source of gastric lipase?
stomach
what are the substrates of pepsin?
proteins
what are the substrates of gastric lipase?
lipids
what is the product of pepsin after its substrates?
polypeptides
what is the product of gastric lipase after its substrates?
Fatty acids
what enzymes does the pancreas produce?
pancreatic amylase, pancreatic lipase, trypsin, chymotrypsin, carboxypeptidase, aminopeptidase, and nucleases
what is the source of pancreatic amylase?
pancreas
what is the source of pancreatic lipase?
pancreas
what is the source of trypsin?
pancreas - released in inactive form
what is the source of chymotrypsin?
pancreas - released in inactive form
what is the source of carboxypeptidase?
pancreas - released in inactive form
what is the source of aminopeptidase?
pancreas - released in inactive form
what is the source of nucleases?
pancreas
what are the substrates of pancreatic amylase?
Starch and Glycogen
what is the substrate of pancreatic lipase?
Lipids
what are the substrates of trypsin?
polypeptides
what are the substrates of chymotrypsin?
polypeptides
what are the substrates of carboxypeptidase?
polypeptides
what are the substrates of aminopeptidase?
polypeptides
what are the substrates of nucleases?
Nucleic acids
what is the product of pancreatic amylase after its substrates?
Disaccharides (Sucrose, Lactose, and Maltose)
what is the product of pancreatic lipase after its substrates?
fatty acids, glycerol
what is the product of trypsin after its substrates?
peptides
what is the product of chymotrypsin after its substrates?
peptides
what is the product of carboxypeptidase after its substrates?
amino acids, peptides
what is the product of aminopeptidase after its substrates?
amino acids, peptides
what is the product of nucleases after its substrates?
nucleotide
what enzyme do the cells of the intestinal mucosa produce?
Enterokinase, peptidase, dipeptidase, tripeptidase, sucrase, lactase, maltase, intestinal lipase
what is the source of enterokinase?
cells of intestinal mucosa
what is the source of peptidase?
cells of intestinal mucosa
what is the source of dipeptidase?
cells of intestinal mucosa
what is the source of tripeptidase?
cells of intestinal mucosa
what is the source of sucrase?
cells of intestinal mucosa
what is the source of lactase?
cells of intestinal mucosa
what is the source of maltase?
cells of intestinal mucosa
what is the source of intestinal lipase?
cells of intestinal mucosa
what is the substrate from enterokinase?
trypsinogen
what is the substrate from peptidase?
peptides
what is the substrate from dipeptidase?
dipeptides
what is the substrate from tripeptidase?
tripeptides
what is the substrate from sucrase?
sucrose
what is the substrate from lactase?
lactose
what is the substrate from maltase?
maltose
what is the substrate from intestinal lipase?
triglycerides
what is the product of enterokinase after its substrates?
converts trypsinogen into active trypsin
what is the product of peptidase after its substrates?
amino acids, dipeptides, and tripeptides
what is the product of dipeptidase after its substrates?
individual amino acids
what is the product of tripeptidase after its substrates?
individual amino acids
what is the product of sucrase after its substrates?
glucose and fructose
what is the product of maltase after its substrates?
two molecules of glucose
what is the product of lactase after its substrates?
glucose, galactose
what is the product if intestinal lipase after its substrates?
glycerol and fatty acids
what is mechanical digestion?
breaking something down into smaller pieces, not altering chemical structure
what is chemical digestion?
a chemical reaction breaks down food
what is necessary for chemical digestion?
an enzyme
where does chemical digestion happen in the digestive system?
every part
what is secretion?
things move from inside the cell to outside the cell
what is absorption?
things move from outside the cell to inside the cell
what is the alimentary canal?
tube from mouth to esophagus, stomach, small intestine, large intestine, and anus
what are the accessory organs to digestion?
salivary glands, liver (for bile), and pancreas
what do goblet cells secrete?
mucus
where is the highest density of goblet cells?
large intestine
what is the job of the large intestine
absorb water
what are the finger like projections in the large intestine called?
villi
describe the mucosa layer of the alimentary canal wall:
lines the lumen, tissue types can vary (esophagus - stratified squamous epithelial, stomach - simple columnar epithelium)
describe the submucosa layer of the alimentary canal wall:
where the blood vessels are found, also gives some structure to organs
describe the muscularis externa layer of the alimentary canal wall:
smooth muscle, longitudinal and circular, important to push things and for movement
describe the serosa of the alimentary canal wall?
outermost layer (aka visceral peritoneum) covers the organs in the abdominopelvic cavity
describe sphincters:
encountered when we go from one organ to another, ring of circular muscle that helps control when things move from organ to organ (can completely close off an organ)
describe autonomic innervation:
talked to by both sympathetic and parasympathetic (dual innervated)
what does the sympathetic nervous system do for digestion?
inhibits/discourages activity (don’t need to digest food during fight or flight)
what does the parasympathetic nervous system do for digestion?
promotes/encourages activity