VIROLOGY (APOLLON)

C. Virion

A mature virus particle containing a nucleic acid core surrounded by a protein coat, with or without envelope, is called a:

A. Nucleocapsid

B. Genome

C. Virion

D. Capsumer

B. DNA and RNA

Viruses are characterized by the presence of:

A. Mitochondrial DNA

B. DNA and RNA

C. Ribosomal RNA

D. RNA

B. Poxvirus

What is the largest DNA virus?

A. Herpesvirus

B. Poxvirus

C. Adenovirus

D. Parvovirus

D. Enterovirus

Which of the following is the smallest RNA virus?

A. Paramyxovirus

B. Togavirus

C. Rhabdovirus

D. Enterovirus

A. Attachment and penetration

What is the first step in the replication cycle of a virus?

A. Attachment and penetration

B. Assembly of virion

C. Release

D. Uncoating

D. Helical or icosahedral

The virus capsid morphology is:

A. Square or round

B. Long or short

C. Ribbon-like or square

D. Helical or icosahedral

A. Nuclear or cytoplasmic membrane

From what part of the virus is the envelope acquired?

A. Nuclear or cytoplasmic membrane

B. Nucleus or cytoplasm

C. Capsomeres or genomes

D. mRNA or DNA

B. Nucleus or cytoplasm

Where is the site of virion assembly?

A. Capsomere

B. Nucleus or cytoplasm

C. Genomes

D. Membranes

C. Herpesviridae

Which of the following is a DNA virus?

A. Retroviridae

B. Orthomyxoviridae

C. Herpesviridae

D. Paramyxoviridae

A. Pseudomyxoviridae

Which of the following is an RNA virus?

A. Pseudomyxoviridae

B. Papoviridae

C. Herpesviridae

D. Pcxviridae

C. 4 C

Specimens collected for virus isolation should be kept at:

A. 37 C

B. 20 C

C. 4 C

D. -20 C

A. -70 C

At what temperature should clinical specimens suspected of containing viruses kept for transport that takes days?

A. -70 C

B. 37 C

C. 4 C

D. -10 C

B. Herpesviricae

In what family of viruses, after primary infection, does an individual become latently infected and then the infection can be reactivated?

A. Adenoviridae

B. Herpesviricae

C. Poxviridae

D. Papovaviridae

C. Human embryonic fibroblasts

Cytomegalovirus isolation is best accomplished using:

A. Monkey kidney cells

B. A549 cells

C. Human embryonic fibroblasts

D. Embryonated hens eggs

A. Rabies

Which of the following viruses causes acute central nervous system disease in humans and animals?

A. Rabies

B. Influenza

C. Mumps

D. Measles

D. AOTA

What specimen/s should be collected from a patient with suspected enteroviral meningitis?

A. Stool

B. Throat swab

C. Cerebrospinal fluid

D. AOTA

B. Hemadsorption assay

Influenza A viruses can be detected in cell cultures by.

A. Complement-fixation test

B. Hemadsorption assay

C. Immunoperoxidase test

D. Hemagglutination-inhibition test

A. Monkey kidney cells and embryonated hens eggs

The best host systems for influenza virus isolation are:

A. Monkey kidney cells and embryonated hens eggs

B. Monkey kidney cells and human embryonic fibroblasts

C. Human embryonic fibroblasts and embryonated hen's eggs

D. Monkey kidney cells and A549 cells

B. Hexon

What common antigen is cross-reactive in all human adenoviruses?

A. Fiber

B. Hexon

C. Hemagglutinin

D. Capsomere

D. Segmented RNA genome

The following characteristics are similar in both influenza and parainfluenza viruses, except:

A. Helical symmetry

B. Lipid envelope

C. Budding from cytoplasmic membrane

D. Segmented RNA genome

A. Neuraminidase and hemagglutinin

Myxoviridae virus envelope contains both:

A. Neuraminidase and hemagglutinin

B. Lipoprotein and nonsegmented nucleocapsid

C. Lipid and double stranded DNA

D. Hemagglutinin and nonsegmented nucleocapsid

B. Poxvirus

Eosinophilic cytoplasmic inclusions are elementary bodies of the:

A. Herpesvirus

B. Poxvirus

C. Poliovirus

D. Papilioma virus

B. Rubella virus

German measles is caused by:

A. Rubeola virus

B. Rubella virus

C. Varicella-zoster virus

D. Vaccinia virus

C. Mild form of smallpox

What is an alastrim infection?

A. Smallpox

B. Chickenpox

C. Mild form of smallpox

D. Measles

D. A and B

Which of the following laboratory procedures is routinely used for the detection of hepatitis B virus (HBV in blood donors)

A. Solid-phase RIA

B. ELISA

C. Culture

D. A and B

C. Direct electron microscopy

Which of the following laboratory procedures is the most rapid method for diagnosis of a virus infection?

A. Culture

B. Serological tests

C. Direct electron microscopy

D. Cytopathic effect (CPE) in cell cultures

B. Throat swab

What specimens should be collected from a patient with suspected influenza?

A. Stool

B. Throat swab

C. Urine

D. AOTA

D. Reovirus

What virus group contains a double-stranded, segmented RNA genome?

A. Herpesvirus

B. influenza virus

C. Parainfluenza virus

D. Reovirus

A. Acid resistance

Enteroviruses can be differentiated from rhinoviruses by:

A. Acid resistance

B. Size determination

C. Ether stability

D. Ribonuclease treatment

C. Rotavirus

What virus is the most frequent cause of gastroenteritis in children during the winter months?

A. Infuenza viruses

B. Adenoviruses

C. Rotavirus

D. Hepatitis A virus

A. Herpesviruses

All of the following groups of viruses are resistant to ether treatment, except:

A. Herpesviruses

B. .Adenoviruses

C. Enteroviruses

A. Negative staining

The most common method for rapid electron microscopy examination is:

A. Negative staining

B. Acid-fast staining

C. Gram stain

D. Periodic acid-Schiff stain

C. Morphology

Various virus groups can be differentiated in negatively stained specimens by their;

A. Envelope

B. Cytoplasmic membrane

C. Morphology

D. Nucleus