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acidosis
pH less than 7.35
alkalosis ph
more than 7.45
Normal PaCO2 range
35-45 mmHg
Normal HCO3
21-27
high pH normal CO2 low HCO3
metabolic alkalosis
Normal HCO3 ranges
respiratory
Normal CO2
metabolic
What causes respiratory acidosis
Hypoventilation
What causes respiratory alkalosis
Hyperventilation
Most common causes of metabolic alkalosis
excessive diuresis
excessive loss of gastric secretion
Hypotonic fluids
goes OUT of the vessel Into the cell
Isotonic fluids
stays where I put it
HypErtonic fluids
Enter the vessel from the cells
Bolus fluid rate
20 ml/kg
Maintence fluid rate
4/2/1 rule
mainteance fluid rate for a 70 kg patient
10 x 4= 40
10 x 2= 20
50 x 1=50 50
total 110ml/hr
When altered, fluid and electrolyte should be corrected in the following order:
volume
pH
potassium, calcium, magenesium
sodium and chloride
Hyponatremia usually due to
water excess
Hyperkalemia causes
eKg changes
U wave on ekg
hypokalemia
Hypocalcemia most common cause
CKD
Signs of hypocalemia
Chovstek sign
Trousseau sign
chornic kindey disease suration
mimimum of 3 months
AKI vs CKD
AKI (acute kidney injury)
-sudden
-commonly caused by injury or necrosis
-oliguria
-elevated creatinine
-reversible
-infection causes death
CKD (chronic kidney disease)
-gradual/years
-caused by diabetic neuropathy
-GFR is
-kidney damage occurs after 3 mo
-CAD causes death
Emergency indications for Dialysis
AEIOU
Acidosis that is not responding
Electrolytes
Intoxication
Overloud in volume
Uremia
What distinguses bursal fluid from cellulitis
ultrasound the bursa
T/F Do not aspirate a purely microtrauamtic bursitis
true
When should a bursa be aspirated
when infection is suspected
first line for bursistis
iv antistaph abx
tense throbbing painful distal pulp
felon
A deep space infection of a digit's flexor tendon sheath, usually resulting from penetrating volar trauma. It is classified as a high-risk, low-prevalence emergency.
flexor tenosynovitis
kanavel's 4 cardinal signs
-Symmetric/*fusiform* swelling of digit
-Tenderness along entire tendon sheath (late finding)
-Severe pain with passive extension (earliest finding)
-Finger held in mild flexion
flexor tenosynovitis tx
iv abx
most common cause of osteomyelitis
MSSA
The diagnosis of osteomyelitis
culture from bone biopsy
most common site for compartment syndrome
calf
what is needed after all post reductions
post reduction films
superir reduction technique for pain contrpl
FARES
An isolated single bone forearm fracture needs
imaging of both elbow and wrist
fracture or dislocation with tented skin
reduce ASAP
KANAVEL 4 signs + volar puncture
IV ABX and emergent hand surgery, no imaging
first 5 min steps
1. airway and vitals
2. glucose check
3. who saw them last
4. focused exam
at what time frame are stroke patients eligible for iv thrombolysis
0-4.5 hours
T/F a low NIHSS stroke score can still be a disabling stroke
true
First-line IV thrombolysis
Tenecetplase 0.25 mg/kg IV bolus, max 25 mg
tenecetplase window
less than 4.5 hours in eligble patients with disabling deficets
What study catches a large vessel occlusion
CTA
LVO treatment
EVT
target BP before IV thrombolysis
less than 185/110
short term treatment for TIA
aspirin + clopidogrel short term then single antiplatelet therapy
star shapped blood in the cisterns and fissures
subarachnoid hemmorhage
crescent on the convexity crosses suture lines
subdural hematoma
hyperdense blood within brian parenchya
intracerbral hemorghage
Intracebral hemorhage bundle
control bp + reverse anticoagulation + call neurosuergy
warfarin reversal agent
4F-PCC + vitamin K 10 mg IV
Dabigatran reversal agent
Idarucizumab
factor Xa inhibitor reversal agent
4F-PCC
Heparin reversal agent
Protamine
What does a subarachnoid patient need within 6hours
CT
If you suspect subarachnoid and the CT is normal what do you do next
lumbar puncture
headache + seizure + focal deficits + papiledema + prothrombotic like pregnancy/postpartum
Cerebral venous thrombosis
Proptosis + chemosis + painful othmalgia
cavernous sinus thrombosis
Prolonged confusion, lateral tongue injury, or a convincing postictal period → favors
seizure
Vasovagal-type prodrome and rapid return to baseline → favor
syncope
Treat ongoing convulsive seizure activity at
5 min
status epilepticus tx
Lorazepam at 5 min
still seizing after lorazepam give
Levetiracetam 60 mg/kg IV (max 4.5 g) OR fosphenytoin 20 mg PE/kg IV (max 1.5 g PE)
Persistent seizure despite adequate benzodiazepine plus second-line therapy =
refractory status and requires escalation to airway control, continuous anesthetic therapy, and EEG
hypeventilation is a _______
TEMPORARY BRIDGE
Patients who need CT before LP because
focal neurologic deficits, new seizure, papilledema, significant immunocompromise, or markedly impaired consciousness
UNSTABLE
what is given afetr LP in bacterial men
dexamethasone +empric abx
For HSV encephalitis, think:
Fever
Behavioral/personality change
Confusion
Aphasia or focal findings
Seizure
Temporal-lobe abnormalities
high risk head injury
GCS
A normal head impulse, direction-changing/vertical nystagmus, or skew should raise concern for a
central cause
Progressive symmetric weakness with decreased reflexes
Guillain-Barré:
Guillain-Barré tx
IVIG or plasma exchange
NO STEROIDS
alling level of consciousness, new fixed pupil, and posturing are emergency findings.
herniation
3 things before any diagnosis made
glucose level
last known well
focused exam
Hot, dry, mydriatic
Agitation/confusion
Decreased bowel activity
Urinary retention
anticholinergic
Hot and agitated
Mydriasis
Tachycardia/hypertension
Diaphoresis
Sympathomimetic
Miosis
Secretions
Bronchorrhea/bronchospasm
GI/GU hyperactivity
cholinergic
Rapid onset of clonus and hyperreflexia
serotonin syndrome
lead pipe rigid + diminished reflex days after a med
neuroepileptic malignant
tx for malignant hyperthermia
Dantrolene
qrs greater than 100
sodium channel block
Terminal R in aVR
sodium channel block
sodium channel blockage tx
sodium bicarb
the Rumack-Matthew nomogram applies when
there is a signle acute ingestion
the Rumack-Matthew nomogram does NOT apply when
repetaed ingestions
unkown time of ingestion
IV NAC most effective
within 8 hours
Tinnitus + tachypnea/hyperpnea + altered mental status
Salicylates toxicity
What acid base disturbance do salicylates cause
respiratory alkalosis + anion gap metabolic acidosis
Salicylates toxicity tx
Bicarb bolus then bicarb infusion
what should be avoided in Salicylates toxicity
intubation
heat exhaustion vs heat stroke
stroke has mental status changes
delrium vs psychosis
delirum: INATTENTION with abnormal vitals
fda approved to treat frost bite
Iloprast