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microbes
simplest but most successful organism on earth. Lives everywhere, eats almost anything, invisible to the naked eye. More of these on humans than cells in humans.
bacteria classification
capsule, cell wall, cell membrane, chromosome, plasmid (one or two), flagellum, ribosome
cocci
spherical bacteria
bacili
rod shaped bacteria
spirilla
spiral shaped bacteria
gram stain
dyes colorless bacteria, binds to the peptidoglycan layer within the cell wall
gram positive
appears purple, thus has multiple layers of peptidoglycan
gram negative
appears pink, thus has a thin layer of peptidoglycan. The microbe will be penicillin resistant
binary fission
the way bacteria replicate and divide
conjugation
bacteria transfers a copy of its DNA to another bacteria through direct contact
transduction
a virus containing DNA from previous host infects a new bacteria, passing on genetic information it may not have had
transformation
a bacteria can take up DNA (potentially some alleles it did not carry) from its surroundings
heterotroph
cannot create its own food
autotroph
is capable of creating its own food
chemoorganotrophs
feeds on organic molecules (carbon-based)
chemolithotrophs
feeds on inorganic molecules
photoautotrophs
use energy from sunlight to produce glucose (photosynthesis)
cynobacteria
modern cells that resemble the first photosynthetic organisms from 2.6 billion years ago. These created our oxygen-rich atmosphere we live in today.
aerobic bacteria
require oxygen for growth
anaerobic bacteria
do not require oxygen for growth
probiotic therapy
large number of benign bacteria are introduced to displace harmful bacteria. Includes lactobacillus, a good bacteria.
pathogenic bacteria
cause disease
sepsis
infection of bloodstream that leads to inflammation
septic arthritis
targets joints
toxic shock syndrome
staph bacteria get into bloodstream and produce toxins
endocarditis
bacteria affects areas in your heart valves
e. coli
group of bacteria that lives in the gut. Usually harmless, but some strains can cause infections and release toxins. Can come from contaminated foods, beverages, water, surfaces, etc.
archaea
thrive in habitats too extreme for most other organisms.
non-extremophile archaea
includes members of the human gut
protists
the first eukaryotes to develop organelles, and can be harmful
diatoms
microscopic, unicellular algae, make up a major portion of phytoplankton
malaria
caused by blood parasite protist called plasmodium. People with sickle-cell disease are immune to this.
viruses
are not cells, consists of a capsid, genetic material, plasma membrane, and glycoproteins
capsid
protein shell of a microbe
glycoproteins
on the surface of a virus; determines which host species and which tissues the virus can infect
virus replication
by hijacking a living cell. They insert their own genetic material into the host cell’s DNA, forcing it to make copies.
DNA viruses
have DNA sequences that remain stable over time due to error-checking mechanisms during DNA replication. Vaccines for these last for a lifetime.
RNA viruses
have no error-checking mechanisms, thus they continuously mutate and are more difficult to target with vaccines
antigenic drift
arises from the accumulation of mutations in the virus genes that code for virus-surface proteins that host antibodies recognize. This results in a new strain of virus that is not attacked by existing antibodies
antigenic shift
sudden change in antigenicity caused by the recombination of the genome, resulting in a new subtype of virus
antigen
foreign substances that trigger an immune response
antibody
proteins produced by the body to fight antigens
retrovirus
contains reverse transcriptase, which is error-prone, leading to frequent mutation