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The Respiratory system includes
thoracic cavity, airways leading to the lungs, and the lungs
everything in the thoracic cavity is protected by
the rib cage
the thoracic cavity runs from
clavicle to the diagragm
what seperates the thoracic and abd cavities
diaphragm
mediastinum
space between lungs that includes the heart, great vessels, trachea, esophagus, thymus, lymphatics, nerves, fibrous tissue and fat
what is included in the upper respiratory tract
nose, nasal cavity, and pharynx
nose
primary passageway of air
nasal cavity
large air-filled space that includes the superior, middle, and inferior nasal conchae
pharynx
connects the mouth (oropharynx), nose (nasopharynx) and throat (laryngopharynx) and is also shared by the digestive system
what does the lower respiratory tract consist of
larynx, trachea, lungs (bronchi, bronchioles and alveoli)
parts of larynx
voice box, thyroid cartilage, cricoid cartilage, epliglottis
voice box
involved in breathing, swallowing, and talking
thyroid cartilage
protects voicebox
cricoid cartilage
structural support, keeps airway open
epiglottis
composed of elastic cartilage and is a valve that covers the entry of larynx to prevent food from entering trachea
opens when inhale, closed when swallow
trachea
windpipe, tough flexible tube that begins around c7 and ends at T5
trachea is ____ to esophagus
anterior
tracheal ligaments are attached to
cricoid cartilage
bronchial tree anatomy
trachea → bronchi→bronchioles
where does trachea bifurcate into L and R main bronchi
carina
Rt bronchus is ___ and _______ than Lt
wider and more vertical
bronchi have ____ in their walls while bronchioles don’t
cartilage
primary bronchi branch into
secondary bronchi and tertiary, then bronchioles, respiratory bronchioles, alveolar ducts, and alveolar sacs
bronchial epithelium is lined by cilia and goblet cells that secretes mucus to make sure
lungs don’t stick together
alveoli are present in
respiratory bronchioles but most numerous in alveolar sacs
Alveoli
where oxygen and carbon dioxide are exchanged
Type 1 alveolar cells
very thin and spread over surface of alveoli (covers 95% of alveolar surface), main role is gas exchange b/w alveoli and pulmonary capillaries
Type 2 alveolar cells
make surfactant and macrophages; more spreadable
what does surfactant do
a chemical that reduces the surface tension of a liquid making it more spreadable, mix of fat and proteins and helps prevent alveolar collapse and lungs sticking together
alveolar macrophages
WBCS that help remove particulate matter
type 2 cells and turn into type 1
during lung injury
lobes of the lungs
rt:3 lobes (upper, middle, lower)
lt lung: 2 lobes (upper lower)
fissures
deep groves or clefts that separate lobes of the lungs
2 in rt (horizontal, oblique)
1 in lt (oblique)
hilum of lung
depression in the mediastinal surface
hilium of lung acommodates
bronchi, pulmonary blood vessels, lymphatic vessels, and nerves
visceral pleura
double-layered serous membrane that adheres to the surface of the lungs, including fissures that separate the lobes
the visceral pleura provides
lubrication and facilitates movement of the lungs during breathing
parietal pleura
outer layer of the pleura and adheres to thoracic wall, mediastinum, and diaphragm
pleural cavity
space b/w the parietal and visceral pleura
pleural cavity contains pleural fluid which allows for
lubrication and smooth breathing
lungs are suppiled with lymphatic vessels that travel toward
hilium of the lungs w/ airways and blood vessels raching lymph nodes and cont into mediastinum
Pulmonary arteries pathway
pulmonary artery —> form R and L pulmonary arteries and follows bronchial tree —> follow bronchi and bronchioles, dividing with them until they reach the alveoli
each alveolus is supplied by
a terminal arteriole, which gives rise to approx. 1000 capillaries per alveolus
the pulmonary capillaries drain into what and form into
pulmonary veins; left atrium
order of blood flow
1) deoxygenated blood is brought to the RA through vena cava
2) deoxygenated blood from RA moves to RV and pumped to pulmonary arteries
3) blood becomes oxygenated
4) oxygenated blood from the lungs is carried by the pulmonary veins from lung to LA
5) the oxygenated blood from LA moves to LV and is pumped to body tissues via aorta
lungs recieve blood from aorta through
bronchial arteries
anastomoses
connection b/w 2 passageways
tidal volume
volume of air breathed out in a normal breath
functional residual capacity
volume of air in the lungs at the end of a normal breath
total lung capacity
volume of air in the lungs after you inhale as much as possible
residual volume
volume of air left in lungs after a complete forceful exhalation
compliance
change in volume or change in pressure of air in the lungs
closing capacity
volume of air in the lungs when closure begins bronchioles collapse
perfusion and ventilation are not evenly distributed in the lungs, so its different
in upright and supine position
V/Q in upright position
V of lower portion of lungs is 150% that of the apex
Q- 3-5x more blood flow in the base of the lungs
important b/c injection can sink to the bottom (create an ombre)
V/Q in suine position
V is more uniform top to bottom but there is a gradient from front to back
ventilation exceeds blood flow by how much in upper zones, and what is going on in middle and lower zoons?
upper zones= exceeds by 2:1 to 3:1 in upper zones
middle zones= more closley matched
lower zones: blood flow exceeds ventilation
how large are capillaries
7-10 micrometers in diamter
injecting MMA= blocks less than 0.1% of capillaries so this why its safer