Chapter 3: Macromolecules

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What are the six most common elements in biological molecules?

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1

What are the six most common elements in biological molecules?

C, H, N, O, P, S

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2

which type of bond involves electrons transferred to one atom forming cations and anions?

ionic

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3

which type of bond involves equal sharing of electrons?

non-polar covalent

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4

which type of bond involves unequal sharing of electrons?

polar covalent

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5

Which bond involves electrostatic attraction between H and N/O

Hydrogen bond

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6

Strength of hydrogen bonds is ___. Compared to other bonds, hydrogen bonds are the (strongest/weakest).

additive, weakest

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7

What are amphipathic molecules?

molecules that have both hydrophilic and hydrophobic properties.

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8

What are functional groups?

small reactive groups of atoms that give larger molecules specific chemical properties

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9
<p>Which functional group?</p>

Which functional group?

Hydroxyl

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10
<p>Which functional group?</p>

Which functional group?

Carbonyl

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11
<p>Which functional group?</p>

Which functional group?

carboxyl

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12
<p>Which functional group?</p>

Which functional group?

Amino

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13
<p>Which functional group?</p>

Which functional group?

Phosphate

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14
<p>Which functional group?</p>

Which functional group?

sulfhydryl

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15

Carbons that are linked to four different atoms or functional groups are asymmetric. They can take one of two positions, known as

isomers

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16

isomers that are mirror images of each other

stereoisomers

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17

isomers that have the same chemical formula but different arrangement of atoms

structural isomers

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18

process that forms monomers through the addition of water

hydrolysis

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19

process that forms a polymer and produces water

dehydration synthesis

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20

which major biological molecule is not considered a macromolecule?

lipids

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21

carbs stored in plant cells as ___ and in animal cells as ___

starch, glycogen

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22

general ratio of 1C:2H:1O

carbohydrates

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23

what is the monomer for carbohydrates?

saccharide

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24

What is the bond between monomers called in a disaccharide?

glycosidic bond

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25

describe the three types of lipids

Neutral lipids - stored and used as an energy source (two types - oils and fats)

phospholipids - form cell membranes

steroids - serve as hormones that regulate cellular activities

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26

What is a fatty acid?

contains a single hydrocarbon chain with a carboxyl group (-COOH) at one end

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27

triglycerides form by ___ between three-carbon glycerol (an ___) and three fatty acid side chains

dehydration synthesis, alcohol

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28

what bond forms between a fatty acid and the glycerol to form a triglyceride? Where does it form?

An ester linkage, between the -COOH of the fatty acid and the -OH of the glycerol.

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29

as chain length increases, fatty acids

become less water-soluble and more oily.

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30

What is a monounsaturated fatty acid? What is a polyunsaturated fatty acid?

A fatty acid with one double bond. a polyunsaturated acid has more than one double bond.

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31

functions of triglycerides

energy reserves in animals, fatty tissue for mammals and birds, and waterproofing bird feathers

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32

In a phospholipid, which end is polar and hydrophilic?

the end with the phosphate group

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33

Steroids (structure)

based on a framework of four carbon rings

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34

What is the most common type of steroid? Describe its structure.

Sterols. They have a single polar OH group linked to one end of the ring framework, and a complex nonpolar hydrocarbon chain at the other end

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35

What type of molecule is cholesterol?

A sterol

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36

How do sex hormones differ in structure?

Varying functional groups

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37

What are the predominant molecules in cells?

Proteins

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38

What is the monomer of proteins?

amino acids

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39

What are protein polymers called?

peptides/polypeptides/proteins

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40

Describe the basic structure of an amino acid.

A central carbon attached to an amino group, a carboxyl group, a hydrogen and a variable R group.

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41

Do amino acids act as acids or bases?

They can act as either.

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42

Primary structure of proteins

The unique sequence of amino acids forming a polypeptide

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43

Secondary structure of proteins

twists and turns of the amino acid chain

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44

Tertiary structure

folding of the amino acid chain into an overall 3D shape

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45

Quaternary structure of proteins

formed from more than one polypeptide chain

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46

alpha helix

twisted into a regular right-hand spiral

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47

beta strand

zigzags in a flat plane, forming a sheet

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48

What is denaturation?

Unfolding a protein from its active conformation

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49

Chaperonins

guide proteins that bind temporarily with new proteins to direct their conformation toward the correct tertiary structure

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50

What are functional domains?

subdivisions

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51

monomer for nucleic acids

nucleotides

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52

parts of a nucleotide

A nitrogenous base (formed from rinds of carbon and nitrogen atoms), a five carbon ring shaped sugar, and one to three phosphate groups

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53

What are the two types of nitrogenous bases?

pyrimidines and purines

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54

Pyrimidine structure, examples

one carbon-nitrogen ring. U, T, C

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55

Purines structure, examples

two carbon-nitrogen rings. A, G

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56

How do DNA nucleotides and RNA nucleotides differ?

DNA contains a deoxyribose sugar. DNA nitrogenous bases are A, T, G, C

RNA contains a ribose sugar. RNA nitrogenous bases are A, U, G, C

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57

What bonds are between two nucleotides?

a phosphodiester bond

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58

One nucleotide is linked to the next by a bridging phosphate group between the ___ carbon of one sugar and the ___ carbon of the next

5’, 3’

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59

What are the sides of the ladder in a DNA molecule? What are the rungs of the ladder?

The sides of the ladder are the sugar-phosphate backbones. The rungs are nitrogenous bases

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60

DNA base pairs

Adenine-Thymine, Guanine-Cytosine

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61

ATP structure

adenine, ribose, three phosphates

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62

ATP is formed by ___ and broken by ___

dehydration synthesis, hydrolysis

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