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1) The functional cell, responsible for sending impulses that are sensory and motor, in the nervous
system, is known as
a. Ganglions
b. Neurons
c. Neuroglia
d. A and b are correct
e. B and c are correct
Neurons
2) Which of the following statements describes a neuron the best
a. Is a bundle of fascicles and is surrounded by DRCT known as perimysium
b. Is an excitable cell that generates and carries electrical signals
c. Is responsible for the myelination of axons
d. It is only found branching from the CNS
e. It only innervates muscle fibers
Is an excitable cell that generates and carries electrical signals
3) What is the primary role of autonomic ganglia in regulating functions such as blood pressure at
the target level
a. They directly innervate target organs without synapsing
b. They serve as relay stations where preganglionic neurons synapse with postganglionic
neurons
c. They generate action potentials independently from the central nervous system
d. They inhibit all autonomic reflexes to maintain homeostasis
e. They help as the connection between the autonomic neuron and the target cell
They serve as relay stations where preganglionic neurons synapse with postganglionic neurons
4) Cells create electrical signals because
a. They are always charged and firing a constant signal at all times
b. They don’t create electrical signals; they just moved them from one place to another
c. They have a “machinery” that fires a signal every so often
d. They respond to a change in their resting membrane potential due to the flux of ions
across their membrane
e. Electricity is their only way of communication
They respond to a change in their resting membrane potential due to the flux of ions across their membrane
5) To which ion(s) is the resting cell membrane most permeable to
a. K, Na, Cl and Ca equally
b. K, Na, and Cl
c. K and Na
d. K, Na, and Ca
e. K only
K only
6) Upon activation of a cell, a sudden (increase, decrease) in Na+ permeability allows Na+ to
(leave/enter) the cell moving (down, against) its concentration gradient and (hyperpolarize,
depolarize, repolarize) the membrane potential of a cell.
a. Increase, enter, down, depolarize
b. Increase, leave, down, repolarize
c. Decrease, enter, against, depolarize
d. Decrease, enter, down, repolarize
e. Increase, leave, against, hyperpolarize
Increase, enter, down, depolarize
7) In the axon terminal, (mechanical, voltage, chemical) gated Ca++ channels open in response to
the activation of the neuron, allowing Ca++ to move from (cytoplasm/ECF) to (cytoplasm, ECF).
This movement causes the release of neurotransmitter from synaptic vesicle.
a. Mechanical, cytoplasm, ECF
b. Voltage, cytoplasm, ECF
c. Chemical, ECF, Cytoplasm
d. Mechanical, ECF, Cytoplasm
e. Voltage, ECF, Cytoplasm
Voltage, ECF, Cytoplasm
8) Which of the following defines a graded potential the best
a. Is a change in membrane potential with varying degrees of magnitude
b. The stronger the triggering event the stronger the graded potential
c. It is decremental as it moves down the soma towards the action hillock
d. It is regulated by IPSPs and EPSPs
e. All of them are true
All of them are true
For the following 3 questions you will need to look at the following diagram
B
X
A
C
Information given: An EPSP from neuron A causes a
10 mV change (from RMP); an IPSP from neuron B
causes a 6 mV change and; an EPSP from neuron C
causes 6 mV change. Use this information to answer
the questions posed below.
Figure 1. Neurons A, B, C and X, where X is the postsynaptic neuron.
Questions:
9) What happens when ALL graded potentials reach the axon hillock (trigger zone) at the same
time?
a. The intensity is too strong and the neuron dies
b. The stimulus is strong enough to reach threshold and create an action potential
c. The summed graded potential of all 3 neurons will be bellow threshold creating no effect
d. Graded potentials never reach the trigger zone no matter what
e. None of these are true
The summed graded potential of all 3 neurons will be bellow threshold creating no effect
10) An inhibitory postsynaptic potential (IPSP) would have what effect on the postsynaptic neuron?
a. Depolarization
b. Repolarization
c. Hyperpolarization
d. Absolute refractory period
e. Depends on the type of receptor on the postsynaptic membrane
Hyperpolarization
11) Given the information above, which of the following would be true?
a. summation of A and X would reach threshold
b. summation of C and A would create an action potential
c. stimulation by A alone would create an action potential
d. stimulation by B would be a subthreshold depolarization
e. summation of B and C would be a graded potential with the net value of 12 mV
depolarization
Summation of C and A would create an action potential
12) Again, given the information above, which of the following would be false?
a. summation of B and C would not change membrane
b. summation of B would be an IPSP
c. summation of C and A = suprathreshold stimuli
d. stimulation by A would depolarize the cell
e. repeated stimulation by A could spatially summate and reach threshold
Repeated stimulation by A could spatially summate and reach threshold
13) Which of the following statements is true when comparing GP with APs
a. Graded potentials vary in magnitude while AP is an all or nothing event
b. Graded potentials are decremental while AP are not
c. Graded potentials have no absolute refractory period while AP do
d. Graded potential occurs at cell body while AP occurs at axon hillock
e. All of the above statements are correct
Graded potentials vary in magnitude while AP is an all-or-nothing event
14) The all-or-none principle states that
a. all stimuli will produce identical action potentials.
b. all stimuli great enough to bring the membrane to threshold will produce action
potentials of identical magnitude.
c. the greater the magnitude of the stimuli, the greater the intensity of the action
potential.
d. only sensory stimuli can activate action potentials.
e. only motor stimuli can activate action potentials.
All stimuli great enough to bring the membrane to threshold will produce action potentials of identical magnitude
15) A greater than normal stimulus can trigger an action potential during relative refractory period
but not during absolute refractory period because during absolute all the Na+ channels are
either closed or inactive so no stimulus can create a change.
a. True
b. False
True
16) Why is it that an action potential cannot reverse and move back towards the cell body when
Na+ channels open in the middle of the axon causing depolarization to spread both ways
a. There are other compounds that prevent the moving back of the action potential
b. Na+ channels don’t open in the middle of the axon
c. The refractory period prevents the AP from going back towards the soma
d. There is an electrical “door” in certain regions of the axon that closes as the AP moves
forward
e. The statement is incorrect; AP does travel both ways
The refractory period prevents the AP from going back towards the soma
17) Which of the following statements is incorrect with respect to AP traveling in a neuron
a. The larger an axon (wider diameter) the slower it is
b. The lower the temperature the faster it is
c. The presence of myelination makes the conduction faster
d. A and B are incorrect
e. They are all correct
A and B are incorrect
18) What happens to the likelihood of firing an action potential when the concentration of ECF K+
increases?
a. The RMP decreases making it impossible to a neuron to fire an AP
b. The RMP becomes more positive and therefore closer to the threshold so a smaller than
normal stimulus could trigger a response
c. The excess K increases activity of the channels for exchange so the depolarization is
more spread over time reducing the frequencies of action potentials
d. A and C are correct
e. B and C are correct
B and C are correct
19) The following are the main steps in the generation of an action potential.
1. sodium channels are inactivated
2. voltage-regulated potassium channels open and potassium moves out of
the cell, initiating repolarization
3. sodium channels regain their normal properties
4. a graded depolarization brings an area of an excitable membrane to threshold
5. a temporary hyperpolarization occurs
6. sodium channel activation occurs
7. sodium ions enter the cell and further depolarization occurs
The proper sequence of these events is
a. 4, 6, 7, 3, 2, 5, 1.
b. 4, 6, 7, 1, 2, 5, 3.
c. 6, 7, 4, 1, 2, 3, 5.
d. 2, 4, 6, 7, 1, 3, 5.
e. 4, 2, 5, 6, 7, 3, 1.
4, 6, 7, 1, 2, 5, 3
20) Which of the following is NOT a method used to clean up the synaptic cleft of the Nt and end
target cell activation
a. Diffusion of Nt into cardiovascular system
b. Up-take of Nt by a neighboring neuron
c. Re-uptake of Nt by original neuron
d. Degradation of Nt by enzyme
e. They ALL represent methods in which we can end transmission by cleaning synaptic cleft
from Nt.
They ALL represent methods in which we can end transmission by cleaning synaptic cleft
from Nt.
1) List the divisions of the brain from the “lowest” to the “highest” in terms of info. processing
1. Medulla Oblongata
2. Cerebrum
3. Hypothalamus
4. Cerebellum
5. Pons
a. 1, 3, 5, 2, 4
b. 3, 4, 2, 1, 5
c. 1, 5, 4, 3, 2
d. 3, 2, 4, 1, 5
e. 1, 5, 3, 4, 2
1, 3, 5, 2, 4 — Medulla → Hypothalamus → Pons → Cerebrum → Cerebellum
2) The 3 vital centers of the CNS are located in
a. Pons
b. Cerebral cortex
c. Midbrain
d. Medulla oblongata
e. Cerebral peduncles
Medulla oblongata — Contains the major vital centers for cardiovascular, respiratory, and digestive reflexes.
3) If a patient lost all regulation of ventilation it would indicate a problem with which areas
a. Hypothalamus
b. Pons
c. Medulla oblongata
d. A and b
e. B and c
B and C — Pons and medulla both help regulate ventilation.
4) What region of the brain is known as the “relay center” for ALL sensory information
a. Thalamus
b. Hypothalamus
c. Epithalamus
d. Corpus collosum
e. Cerebral peduncles
Thalamus — Major relay center for sensory information to the cerebral cortex.
5) An infarct (tissue necrosis/death) in the thalamus after a stroke, could show numbness and
tingling on a patient’s body. This is because
a. The thalamus is the primary motor control center of the brain
b. The thalamus directly generates conscious perception of sensory stimuli
c. The thalamus only processes visual and auditory information
d. The thalamus acts as a relay station for most sensory information before reaching the
cortex
e. The thalamus is primarily involved in regulating autonomic functions and has no role in
sensation
The thalamus acts as a relay station for most sensory information before reaching the cortex.
6) The formation of memories, the ability to make predictions, the mechanics of language,
complex thought and analysis are functions of the
a. Corpus collosum
b. Thalamus
c. Cerebral cortex
d. Cerebellum
e. Arbor vitae
Cerebral cortex — Responsible for higher cognitive functions.
7) Which of the following best explains the role of the hypothalamus in a patient with the following
symptoms: excessive thirst, frequent urination, and difficulty regulating body temperature.
a. It controls voluntary motor movements
b. It is the relay center of the brain
c. It regulates homeostasis of autonomic functions
d. It is responsible for regulating emotions, memory, and visceral organs
e. It has no role in the control of autonomic or endocrine functions
It regulates homeostasis of autonomic functions — The hypothalamus regulates thirst, temperature, endocrine activity, etc.
8) What region of the brain is responsible for emotion, memory, and learning
a. The limbic system
b. The amygdala
c. The cingulated gyrus
d. The insula
e. The hypothalamus
The limbic system — Strongly involved in emotion, memory, and learning.
9) The autonomic nervous system is responsible for the _____________ control of three effector
tissues: cardiac muscle, smooth muscle and ______________
a. Involuntary/somatic tissue
b. Voluntary/somatic tissue
c. Involuntary/glandular tissue
d. Voluntary/glandular tissue
e. Voluntary/skeletal muscle
Involuntary/glandular tissue — ANS controls cardiac muscle, smooth muscle, and glands.
10) The parasympathetic division has __________ receptors between the pre and post- ganglionic
neurons and ________ receptors at the effector
a. Nicotinic/muscarinic
b. Muscarinic/adrenergic
c. Adrenergic/cholinergic
d. Cholinergic/adrenergic
e. Nicotinic/adrenergic
Nicotinic/muscarinic — Parasympathetic: ACh → nicotinic receptors in ganglia; ACh → muscarinic receptors at effectors.
11) The sympathetic division uses ______ as a neurotransmitter for cholinergic receptors and
______ for adrenergic receptors.
a. ACh/ACh
b. NE/E
c. Ach/NE
d. NE/Ach
e. E/Ach
ACh/NE — ACh acts on cholinergic receptors; norepinephrine (NE) acts on adrenergic receptors.
12) Together, alpha and beta receptors are known as _________ receptors, and are found at the
________ of the ________ division
a. Cholinergic/peripheral ganglion/parasympathetic
b. Adrenergic/peripheral ganglion/sympathetic
c. Cholinergic/effector/sympathetic
d. Cholinergic/effector/parasympathetic
e. Adrenergic/effector/sympathetic
Adrenergic/effector/sympathetic — Alpha and beta receptors are adrenergic receptors located on sympathetic effectors.
13) A patient with a disorder in the sympathetic division would show problems with what action
a. Urination
b. Excitement
c. Digestion
d. Defecation
e. Salivation
Excitement — Sympathetic activity produces the “fight-or-flight” response.
14) With the exception of olfaction, all sensory pathways first travel to the __________, which acts
as a relay and processing station.
a. cerebrum
b. thalamus
c. cerebellum
d. hypothalamus
e. medulla oblongata
Thalamus — All major sensory pathways except olfaction relay through the thalamus.
15) Antagonistic control of efferent output is typical of the __________ division.
a. somatic
b. sensory
c. autonomic
d. A and B
e. A and C
Autonomic — The ANS commonly uses antagonistic sympathetic/parasympathetic control
16) A decrease in cerebrospinal fluid production indicates physiological problems with
a. choroid plexus.
b. arachnoid villi.
c. frontal sinuses.
d. pia mater.
e. ventricles.
Choroid plexus — The choroid plexus produces CSF.
17) What type of neuroglia would you say was not working properly if a patient had a drug
administered for a problem in his kidneys but started showing symptoms or effects on his/her
brain?
a. Astrocytes
b. Schwann
c. Oligodendrocytes
d. Microglia
e. Ependymal
Astrocytes — Help form the blood-brain barrier, limiting substances from entering brain tissue.
18) The “enteric division” regulates local activities within which body system
a. Cardiovascular
b. Lymphatic
c. Respiratory
d. Digestive
e. Endocrine
Digestive — The enteric nervous system regulates local digestive activities.
19) Which of the following would be an adequate stimulus for a mechanoreceptor?
a. oxygen
b. cell stretch
c. photon of light
d. cold temperature
e. Ph
Cell stretch — Mechanoreceptors respond to mechanical deformation/stretch.
20) Phasic receptors
a. are quick to adapt to a particular stimulus intensity.
b. slowly decrease the frequency of action potentials generated to a constant stimulus.
c. are attune to parameters that the body must continuously assess.
d. once threshold is reached by a stimulus will always generate action potentials
e. change their sensitivity in phases going from slow to fast
are quick to adapt to a particular stimulus intensity. — Phasic receptors respond strongly initially, then decrease firing during a constant stimulus.
21) The area monitored by a single receptor is called
a. Neural area
b. Receptor field
c. Receptive field
d. Receptor specificity
e. Receptor modality
Receptive field — The area monitored by a single sensory receptor/neuron.
22) A patient comes to see you because they lose balance every time they spin while dancing or
when they turn around really fast. You suspect damage to the hair cells which are found in the
a. Ampulla
b. Vestibule
c. Auricle
d. Saccule
e. Crista
Crista — Cristae in the semicircular ducts detect rotational/angular acceleration.
23) If you close your eyes and someone feeds you a piece of steak or an oyster, you are able to
distinguish between the two textures because of which papilla
a. Fungiform
b. Foliate
c. Filiform
d. Circumvallate
e. They are all associated with taste buds
Filiform — Filiform papillae provide texture sensation but do not contain taste buds.
24) A 35-yo photographer visits the ophthalmologist complaining of difficulty focusing on fine
details while reading and editing images. What structure would you say is the most important to
check
a. Optic disc
b. Retina
c. Fovea
d. Lens
e. Choroid
Fovea — Provides the highest visual acuity and fine-detail vision.
25) A decrease in ones perception of a stimulus whose intensity has not changed due to higher
neural inhibition is known as
a. habituation.
b. convergence.
c. divergence.
d. Adaptation
e. Illusion
habituation — Decreased perception of an unchanged stimulus due to increased neural inhibition.
1) A 25yo woman exercises outdoors on a hot day. Her body temperature rises, triggering
sweating and increased blood flow to the skin, eventually returning her temperature
toward normal levels. This scenario describes:
a Positive feedback
b Permanent maintenance of a fixed internal value
c Homeostasis
d Loss of regulation due to external stimuli
e Variation of body conditions with control mechanisms
Homeostasis
2) A 30yo receives an IV solution with a higher solute concentration than his ICF causing his
cells to shrink. The solution is said to be:
a Hypo-osmotic and hypotonic
b Iso-osmotic and isotonic
c Hyperosmotic and hypotonic
d Hyperosmotic and hypertonic
e Hypo-osmotic and hypertonic
Hyperosmotic and hypertonic
3) A 37yo woman develops a fever and inflammation after an infection. Her body responds
to increased temperature while immune cells simultaneously release signaling molecules
that bind to receptors on nearby cells to coordinate the inflammatory response. Which
of the following best describes the signals involved in this scenario:
a Physical signals include ligands and cytokines; chemical signals include pressure
and temperature
b Physical signals include temperature and pressure, chemical signals include
ligands and cytokines
c Physical signals require receptors, whereas chemical signals do not
d Chemical signals include only hormones, while physical signals include all
immune responses
e None of the above are true regarding physical and chemical signaling
Physical signals include temperature and pressure, chemical signals include ligands and cytokines
4) A 40yo man presents to the ER after a motor vehicle accident. He reports loss of voluntary
movement in his lower limbs but retains involuntary regulation of heart rate and
digestion. After evaluation, you conclude that this division is primarily affected
a Autonomic nervous system
b Sympathetic nervous system
c Parasympathetic nervous system
d Somatic nervous system
e Enteric nervous system
Somatic nervous system