Multipotent progenitor cells

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Last updated 10:38 PM on 2/21/25
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5 Terms

1
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What type of stem cells differentiate into multipotent progenitor (MPP) cells?

Hematopoietic stem cells (HSCs).

2
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How do multipotent progenitor cells differ from HSCs?

They are no longer self-renewing but still retain differentiation potential.

3
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What key surface receptor is detectable on multipotent progenitor cells?

CD34

4
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What is the role of CXCR4 in multipotent progenitor cells?

It interacts with the stromal cell cytokine CXCL12, which helps guide cell migration and differentiation.

5
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What do multipotent progenitor cells ultimately differentiate into?

Lymphoid-primed multipotent progenitor (LMPP) cells.