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drug in class
lithium (Lithobid)
properties/MOA
· Unknown MOA
· Short ½ life
· Low therapeutic index
· Well absorbed orally
King to ↓ suicide, also cheap
effects/adverse rxn
· Polyuria
· Thirst
· Teratogen
· Confusion
GI upset
contraindications
Contraindicated w/ pregnancy, diuretics, NSAIDS, and anticholinergics
nursing info
· NEED to monitor plasma levels q3-6 months r/t narrow therapeutic index
· NSAIDS can ↑ lithium levels by 60%
· Affected by NA levels
Need to take frequently r/t short ½ life