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Embryologic Stages
1. Period of ovum 2. Period of embryo 3. Period of fetus
Period of the ovum
fertilization to 2 weeks
Period of embryo
weeks 3-8 of gestation
Period of fetus
weeks 9-36 gestation
By the time the embryo is 3 weeks old it's length measures approximately—-
3 to 4 mm - from the top of the head to the tail
Pharyngeal arches
three ridges of tissue bulge laterally from the throat area that develop into a number of structures "U" shaped bars of tissue
The open end of the "U" faces posteriorly and surrounds the upper end of the ___
foregut and part of the primitive oral cavity
The fifth arch (of the pharyngeal arches) will ___
degenerate and form nothing of any consequence
The fourth sixth arch (of the pharyngeal arches) are ___
poorly developed and are not readily seen on the emryonic surface
The ones closest to the head are the largest and those farther down are
smaller in size (tail is smaller than head)
The longitudinal section through the embryo of the pharyngeal arches is divided into ___
halves
The body is relatively hollow with the exception of a tube closed at its upper and lower ends and running through the middle of the body cavity, the lining of which developed from—
the endoderm
Foregut
Upper part ; digestive tube from the throat region to the duodenum
Midgut
Middle ; *rest of small intestines as well as the cecum, ascending colon, and most of the transverse colon
Hindgut
Lower ; *descending colon, sigmoid colon, and rectum of large intestine
Where the foregut region and the stomodeum share a common wall found in the location that will become the region between palatine tonsils and an area about 2/3 of the way back from the tip of the tongue
buccopharyngeal membrane
When the buccopharyngeal membrane breaks down at about 4 1/2 weeks?
the connection between the oral cavity and the digestive tract are established
frontal prominence
in the anterior (frontal) view of a 3 week embryo ; forehead area the stomodeum (primitive oral cavity) & the mandibular processes of the mandibular arch
During the ___ embryonic week some changes can be seen
4th
First two small depressions from low on the frontal prominence ; these are the
nasal pits, the beginning of the nasal cavities
The areas on either side of these nasal pits begin to form a ridge and become the
medial nasal process and the lateral nasal process
By the 6th week two medial nasal processes have fused together and along with the two maxillary process, have formed the
upper lip
The lateral nasal process takes no part in forming the upper lip. It gets pushed up and out of the way. True or False?
True
Also at about 6 weeks the nasal pits deepen until they open into the
primitive oral cavity
Mandibular symphysis
formed by the fusion of the mandibular processes at about the seventh week
The ___ and ___ begin to fuse at their lower end and that connection then starts to form perforations in it.
medial nasal ; maxillary processes
Connective tissue flows into the groove and begins to fill in the area that lies between these perforations ; Increase in connective tissue of the upper lip in the area of the groove and the groove fills in and slowly disappears
Migration
If migration fails the tissues will be stretched and will break down as development continues, resulting in separation between the medial nasal process and the maxillary process
Cleft lip
Cleft lip occurs
about the 6th embryonic week
The result of a midline cleft of the upper lip
If two medial nasal processes do not fuse together
The formation of the palate or roof of the mouth involve these processes
Right and left maxillary processes the medial nasal process
Primary palate /or/ premaxilla
The medial nasal processes form a block of tissue that includes the area of the maxillary central and lateral incisors as well as a small "V" shaped wedge of tissue lingual to these teeth back to the incisive foramen
The medial nasal processes also help to form the ___ the wall that divides the nasal cavity into right and left halves
nasal septum (septum = separate into right & left halves)
If a cleft palate is going to develop it will begin somewhere between — If it occurs early the entire palate will be — If it happens near week 11 only the ___ or the ___ will be affected
weeks 7 & 11
Open or cleft
Soft palate; ovula
A combined cleft lip and palate occurs in about ____ births among whites in the United States
1 in 700
For African Americans clefts rate about
1 in 2000
Clefts are more frequent in Asians at about
3 in 2000
Clefts involving only the palate and not the lip, the ratio is about the same for all races, at about
1 in 2500
___ tend to have a higher incidence of cleft lip, or cleft lip with cleft palate, whereas have more isolated incidence of cleft palate
Males ; females
Involves lack of connective tissue migration between both maxillary processes and the fused medial nasal processes
Bilateral cleft lip
External bulges in the future neck region
Pharyngeal arches
Depressions on the neck surface
Pharyngeal grooves
Depressions on the inside
Pharyngeal pouches
Trigeminal nerve
Cranial nerve of the first arch ; fifth cranial nerve
Facial nerve
Cranial nerve of the second arch ; seventh cranial nerve
Small depression in the middle of the posterior tongue This is the point where the thyroid gland begins to develop and then migrates downward eventually lying in the lower front neck region
Foramen cecum
The thyroid gland starts out as a ___ then becomes a ___, and ___ with the glandular tissue developing at the deep end of the tube
cord of cells — tube — grows downward
If for some reason the tube does not grow downward the patients thyroid gland forms into a big red lump at the back of the tongue
Lingual thyroid
Upward growth - forms the anterior part of the pituitary gland and what is known as the pars intermedia or the intermediate part of the gland hormones
Rathke's pouch
Microglossia
the tongue is too small for the mouth ; can cause eating and speech problems
Macroglossia
the tongue is too large for the mouth ; can cause difficulties with speech eating, breathing, and many require surgery and speech therapy
Ankyloglossia
being tongue tied ; too short of a lingual frenum which limits the movement of the tongue