CHAPTER 24: INTRODUCTION TO GLYCOLYSIS

The primary pathway for glucose catabolism in mammalian cells, leading to the production of pyruvate in the cytoplasm.

Glycolysis

The process of glycolysis that occurs in the absence of oxygen, producing lactate and a net gain of two ATP molecules.

Anaerobic glycolysis

A condition characterized by the accumulation of lactate in the body, leading to an acidic environment and potential implications for certain types of cancer therapy.

Lactic acidosis

Adenosine triphosphate, the energy currency of cells, produced during glycolysis.

ATP

Cells that lack mitochondria and rely solely on anaerobic glycolysis for energy production.

Red blood cells

Muscle tissue that relies on anaerobic glycolysis to provide ATP when aerobic oxidation becomes insufficient.

Skeletal muscle

The end product of glycolysis, which can be further oxidized in the mitochondrial TCA cycle.

Pyruvate

The generation of ATP molecules during glycolysis, with a net gain of two ATP molecules in anaerobic glycolysis.

ATP production

The anion form of lactic acid, produced during anaerobic glycolysis and can be converted to pyruvate in liver and cardiac muscle cells.

Lactate

The tight control of glycolysis, ensuring that only enough glucose is metabolized to meet the cell's ATP needs.

Metabolic regulation