anxiety

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Last updated 10:09 PM on 12/1/25
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4 Terms

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Ketamine's Mechanism of Action

Ketamine operates as a channel blocker, specifically by blocking NMDA receptors. Blocking these receptors with competitive inhibitors reduces its efficacy.

2
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Excitatory Neurons

Pyramidal neurons that release glutamate.

3
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Inhibitory Neurons

Parvalbumin neurons that release GABA.

4
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Ketamine's mechanism on neurons

Ketamine selectively blocks glutamate receptors on inhibitory neurons, altering the excitement balance by reducing inhibition and increasing overall neuronal activity.