Drugs acting on the kidneys

What do Thiazide diuretics do?

Act on the distal tubule

What do loop diuretics do?

Act on the loop of Henle

Where does furosemide act?

On the loop of Henle

Furosemide is what type of diuretic?

Loop acting diuretic

What do potassium-sparing diuretics do?

Prevents potassium loss

What type of diuretic is spironolactone?

Potassium-sparing diuretic

Diuretic agents help what?

Manage fluid balance and blood pressure.

What are key loop diuretics?

Furosemide, Bumetanide

What are some main uses of loop diuretics?

heart failure and edema

What are some side effects of loop diuretics?

Hypokalemia, ototoxicity

Where do Thiazide diuretics act?

Distal tubule

What are some key Thiazide drugs?

HCTZ, Chlorthalidone

What are some main uses of Thiazide drugs?

Hypertension, mild heart failure

What are some side effects of Thiazide drugs?

Hyperglycemia, gout

Where do potassium sparing drugs act?

Collecting duct

What are some postassium sparing drugs?

Spironolactone, Amiloride

What are the main uses of potassium sparing drugs?

Heart failure, hypertension

What are some side effects of potassium sparing drugs?

Hyperkalemia, gynecomastia

Where do carbonic anhydrase (CA) drugs act?

Proximal tubule

What is one example of a carbonic anhydrase drug?

Acetazolamide

What are some of the main uses of carbonic anhydrase drugs?

Glaucoma, altitude sickness

What are some side effects of carbonic anhydrase drugs?

Acidosis, stones

Where do osmotic diuretics act?

Multiple sites

What is a key osmotic diuretic drug?

Mannitol

What are some of the main uses of osmotic diuretic drugs?

Cerebral edema

what is a side effect of osmotic drugs?

Electrolyte imbalance