Clin. Theory: EXAM 3 MC

All Multiple Choice Q's from Ch. 11-12

(Ch.11) The blood cells responsible for carrying oxygen are:

Erythrocytes

(Ch.11) When seen on a Wright-stained peripheral blood film, a young red cell that has just extruded its nucleus is referred to as a:

Polychromatophilic cell

(Ch.11) The approximate life span in peripheral blood of a red blood cell is:

120 days

(Ch.11) Which of the following of essential to the oxygen-carrying capacity of a molecule of hemoglobin?

Iron

(Ch.11) A hemoglobin variant resulting in sickle cell anemia in the homozygous state is:

Hemoglobin S

(Ch.11) A principle form of hemoglobin found in the blood of normal adults is:

Hemoglobin A

(Ch.11) The principle form of hemoglobin during intrauterine life and at birth is:

Hemoglobin F

(Ch.11) An irreversible combination of hemoglobin with a sulfa group, incapable of transporting oxygen or reverting to functional hemoglobin, is:

Sulfhemoglobin

(Ch.11) Hemoglobin bound to carbon monoxide with an affinity 100 times that of oxygen is:

Carboxyhemoglobin

(Ch.11) Hemoglobin containing iron in a ferric, rather than a ferrous, state is:

Methemoglobin

(Ch.11) The form of hemoglobin that normally transports carbon dioxide from the tissues to the lungs is:

Reduced hemoglobin

(Ch.11) The form of hemoglobin that normally transports oxygen from the lungs to the tissues is:

Oxyhemoglobin

(Ch.11) The MCV (SI) units of measurement are:

Femtoliters (fL)

(Ch.11) The MCH (SI) units of measurement are:

Picograms (pg)

(Ch.11) The MCHC (SI) units of measurement are:

Grams per deciliter (g/dL)

(Ch.11) The approximate life span in peripheral blood of a mature, inactivated B lymphocyte is:

Months to years

(Ch.11) The approximate life span in peripheral blood of a neutrophil (PMN) is:

About 10 hours

(Ch.11) Which of the following cells is lymphoid in nature?

B cells

(Ch.11) The anticoagulant of choice for a complete blood count (CBC) is:

EDTA

(Ch.11) The use of daily hemoglobin control solution with automated equipment will detect which of the following?

Both accuracy of the measuring device used and deterioration of the hemoglobin reagent

(Ch.11) What is the unit of measurement for hematocrit?

Liters per liter

(Ch.11) What is the unit of measurement for hemoglobin?

Grams per deciliter

(Ch.11) What is the unit of measurement for packed cell volume (SI units)?

Percent

(Ch.11) What is the unit of measurement for platelet count?

Cells x 10^12 per liter

(Ch.11) What is the unit of measurement for red cell count?

Cells x 10^12 per liter

(Ch.11) What is the unit of measurement for white cell count?

Cells x 10^9 per liter

(Ch.11) Assuming normochromic and normocytic red cells, a blood sample with a hemoglobin of 15g/dL would be expected to show a hematocrit of:

45%

(Ch.11) Hemoglovin concentration of color of the average RBC:

MCH

(Ch.11) Measure of the degree of RBC size variability

RDW

(Ch.11) Volume or size of the average RBC:

MCV

(Ch.11) Average concentration of hemoglobin in a riven RBC volume:

MCHC

(Ch.11) Which of the following hematologic tests may not be part of the usual complete blood count?

Reticulocyte count

(Ch.11) Which of the following is a nonspecific screening test for inflammation?

Erythrocyte sedimentation rate

(Ch.11) Which of the following test is used to evaluate the response to therapy in the treatment of iron deficiency anemia?

Reticulocyte count

(Ch.11) Which of the following stains is classified as a Romanovksy stain?

Wright-Giemsa

(Ch.11) For a blood film stained with polychrome Romanovsky-type stain; identify the type component for the cell component: Azurophilic granules

Methylene azure (polychrome methylene blue)

(Ch.11) For a blood film stained with polychrome Romanovsky-type stain; identify the type component for the cell component: Cytoplasmic RNA

Methylene azure (polychrome methylene blue)

(Ch.11) For a blood film stained with polychrome Romanovsky-type stain; identify the type component for the cell component: Eosinophilic granules

Acidophilic (eosin)

(Ch.11) For a blood film stained with polychrome Romanovsky-type stain; identify the type component for the cell component: Hemoglobin

Acidophilic (eosin)

(Ch.11) For a blood film stained with polychrome Romanovsky-type stain; identify the type component for the cell component: Neutrophilic granules

Acidophilic (eosin) and Basophilic (methylene blue)

(Ch.11) For a blood film stained with polychrome Romanovsky-type stain; identify the type component for the cell component: Nuclear DNA

Methylene azure (polychrome methylene blue)

(Ch.11) What is the most probable cause of added or washed-out appearance of all cells?

Overwashing, understaining, underfixing

(Ch.11) What is the most probable cause of the gross appearance of slide being excessively blue, with blue-red erythrocytes and dark, granular leukocytes?

Overfixing, overstaining, underwashing; too-alkaline stain or buffer, or too-thick blood film

(Ch.11) What is the most probable cause of the gross appearance of slide being excessively red with bright-red erythrocytes, pale-blue white cel, and brilliant-red eosinophilic granules?

Understaining, overwashing; too-acid stain, buffer, or water

(Ch.11) What is the most probable cause of large amounts of precipitated stain?

Improper washing or old stain

(Ch.11) Identify the morphologic type for the following causes or descriptions of anemia: Acute blood loss (trauma)

Normochromic-normocytic

(Ch.11) Identify the morphologic type for the following causes or descriptions of anemia: Anemia associated with increased plasma volume (pregnancy and overhydration)

Normochromic-normocytic

(Ch.11) Identify the morphologic type for the following causes or descriptions of anemia: Anemia associated with aplastic anemia from bone marrow suppression

Normochromic-normocytic

(Ch.11) Identify the morphologic type for the following causes or descriptions of anemia: Anemia associated with iron deficiency caused by diet or blood loss

Hypochromic-microcytic

(Ch.11) Identify the morphologic type for the following causes or descriptions of anemia: Anemia associated with thalassemia and other hemoglobinopathies

Hypochromic-microcytic

(Ch.11) Identify the morphologic type for the following causes or descriptions of anemia: Anemia associated with vitamin B12 or folate deficiency

Macrocytic

(Ch.11) What is the term for erythrocytes that show normal color or staining reaction?

Normochromic

(Ch.11) What is an increased variation in size of erythrocytes on the blood film?

Anisocytosis

(Ch.11) What si an increased variation in the shape of erythrocytes on the blood film?

Poikilocytosis

(Ch.11) The presence of anisocytosis and poikilocytosis is reflected in which of the following red cell indices?

RDW

(Ch.11) The presence of polychromasia on a Wright-stained peripheral blood film is associated with which of the following untreated anemias?

Hemolytic anemia

(Ch.11) Which of the following leukemias is most frequently associated with the presence of the Philadelphia chromosome?

Chronic myelogenous

(Ch.11) Which of the following types of leukemia is most associated with children ages 2 to 10 years?

Acute lymphoblastic

(Ch.11) The presence of Auer rods in the peripheral blood is associated with which of the following cells?

Myeloblast

(Ch.11) A white blood cell (WBC) count and a WBC differential are performed. WBC count: 7.0 × 10^9 / L; of 100 WBCs classified: 70% neutrophils, 20% lymphocytes, 7% monocytes, 2% eosinophils, and 1% basophil. The absolute neutrophil cell count is:

4.9 × 10^9 / L

(Ch.11) A patient being treated for metastatic carcinoma was found to have a white cell count of 5 × 10^9 / L with 5 metarubricytes (nucleated red cells) per 100 white WBCs. What is the corrected white cell count for this patient?

4.8 × 10 ^9 / L

(Ch.12) Hemostasis is defined as a process to:

Stop bleeding from an injured blood vessel

(Ch.12) Which of the following peripheral blood cells is involved into hemostasis?

Thrombocytes

(Ch.12) Primary hemostasis results in:

Formation of a platelet plug

(Ch.12) For the control of bleeding, all of the following characteristics are true except:

It is not necessary for platelets to aggregate with one another

(Ch.12) All of the following factors will be inhibited by warfarin-type drugs except:

VIII

(Ch.12) Hemophilia A is a disorder associated with a deficiency of:

Factor VIII

(Ch.12) Which factor is part of the common coagulation pathway?

X

(Ch.12) Which factor is used only in the extrinsic coagulation pathway

III

(Ch.12) Which factor is one used in the intrinsic coagulation pathway?

XII

(Ch.12) Fibrinogen is synthesized in the:

Liver

(Ch.12) Clot removal is accomplished by which of the following systems?

Fibrinolysis

(Ch.12) Protective mechanisms against thrombosis include all of the following except:

Antibodies produced by lymphocytes to block thrombin

(Ch.12) Which of the following is the anticoagulant of choice for routine coagulation assays?

Sodium citrate

(Ch.12) The prothrombin assay requires that the patient’s citrated plasma be combined with which of the following?

Calcium chloride and thromboplastin

(Ch.12) What does the silicate (kaolin) do in the test system for APTI?

It activates tissue thromboplastin

(Ch.12) Which factor is measured by the prothrombin assay?

II

(Ch.12) Which of the following is the most accurate POCT coagulation assay used to monitor heparin?

Activated partial thromboplastin time