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bones, cartilages, joints, and muscles;
ligaments and tendons.
The musculoskeletal system is composed of the __________, ___________, ____________, and _____________, together with associated structures such as _______________ and _______________.
considerable pain and disability;
deform the body
Musculoskeletal disorders can cause ____________ and ___________, and have the potential to _______________.
degenerative arthritis or degenerative joint disease
Osteoarthritis is formally known as ___________ or _____________, characterized by degeneration of joint cartilage.
joint aspiration,
x-ray,
MRI
(3) Tests used to diagnose osteoarthritis
joint aspiration
the test will look for infection or crystals in the fluid; results can help rule out other Medical conditions or other forms of arthritis.
x-ray
can show joint or bone damage or changes related
to osteoarthritis.
Magnetic resonance imaging (MRI)
gives a better view of cartilage and other parts of the joint.
Drug Therapy: NSAIDs, corticosteroids, topical and other
pain relievers
Health Behavior Changes: weight control, rest and relief from
stress on joints
Non-Drug Pain Relief: Heat and cold, TENS (transcutaneous
electrical nerve stimulation), massage
Medical Treatment for osteoarthritis
i. Balanced diet with appropriate kcal for weight
ii. loss or maintenance of appropriate weight
iii. Anti-inflammatory diet
iv. Supplementation with omega-3 PUFA
v. Adequate calcium and vitamin D
vi. Consideration of glucosamine and chondroitin
Nutrition Therapy for osteoarthritis
i. Exercise
ii. Acupuncture
Complement Therapy
Rheumatoid arthritis
an immunologic disease of the joints and related structures.
It is characterized by chronic autoimmune inflammation that begins in the synovial membrane and progresses to Subsequent damage in the joint cartilage
I. Blood test
II. Imaging ests like an X-ray, ultrasound or MRI
(2) Tests used to diagnose rheumatoid arthritis
Erythrocyte sedimentation rate (ESR, or "sed rate") and C-reactive protein (CRP) levels
are markers for inflammation. A high ESR or CRP combined with other clues to the disease
helps make the diagnosis.
Rheumatoid factor (RF)
an antibody found in about 80
percent of people with the disease.
i. Routine monitoring and ongoing care, doctor visits, blood, urine and lab tests, x-rays
ii. Drug Therapy DMARDS, biological response modifiers, analgesics,
iii. NSAIDs, corticosteroids
iv. Health Behavior Changes: Rest and exercise, Joint care, Stress reduction
v. Surgery: Joint replacement, tendon reconstruction, synovectomy
Medical treatment for rheumatoid arthritis
i. Healthful balanced diet
ii. Appropriate calories for maintenance of normal body weight
iii. Avoidance of possible food allergens
iv. Adequate B vitamins
v. Adequate protein, unless with malnutrition
vi. Adequate calcium and vitamin D
vii. Supplementation with ω-3 PUFA
viii. Anti-inflammatory diet*
ix. Intermittent fasting during acute phase
Nutrition therapy for rheumatoid arthritis
exercise, medication, tai chi, spirituality, relaxation techniques
complementary treatment for rheumatoid arthritis
Gout
a disorder of purine metabolism wherein abnormally high uric acid levels accumulate in the blood,
monosodium urate (MSU) crystals
Prolonged high levels of uric acid in the blood may cause build up or formation of needle-like ____________________.
If left untreated, recurrent attacks of gout will result in persistent swelling, stiffness, mild to moderate joint pain, and eventually permanent joint damage and disability
1. Joint fluid test - urate crystals in fluid is visible under a microscope.
2. Blood test - test for uric acid in the blood
3. X-ray
4. Ultrasound
The following tests are used to diagnose gout:
i. NSAIDs to relieve pain and reduce inflammation
ii. Glucocorticoids and colchicine to reduce inflammation
iii. Allopurinol
Pharmacological treatment for gout
1. Purine-restricted (100-150mg/day)
2. Omega 3 FA
3. Low fat, High CHO,
4. Fluid, 3L/day
5. Low kcal (obese); High kcal (underweight)
6. Alcohol-restricted
Dietary recommendations for gout
Axial skeleton
Appendicular skeleton
makes movement in the external environment possible
1/3 organic & 2/3 inorganic
matrix of bone tissue;
dry weight;
osteoporosis
the most common bone disease; severe loss of bone density; deterioration of bone microarchitecture.
DEXA (dual energy x-ray absorptiometry)
- measure bone mineral content and soft-tissue composition
- LBM and FM absorb the x-rays in different degrees, so that the percentage of each can be calculated
- reliable method
- Tissue densities are measured directly and are differentiated
- expensive and requires trained radiology
personnel.
* Generally limited to clinical studies
Paget's disease of bone
bone turnover is accelerated in localized areas