Lilley Ch 8 Gene therapy and Pharmogenomics

gene therapy

a technique that places a gene into a cell to correct a hereditary disease or to improve the genome

Recombinant DNA

artificially produced DNA splices

gene transfer

segments of DNA are injected into the patient's body

D

Which statement regarding gene therapy is accurate?

A) Gene therapy is commonly used for the treatment of disease.

B) During gene therapy, segments of RNA are injected into the patient's body.

C) Bacteria are used for gene transfer.

D) The majority of the world's insulin supply has been produced by recombinant gene technology.

e.coli bacterial genome

used to manufacture a recombinant form of human insulin

eugenics

intentional selection before birth of genotypes that are considered more desirable than others

D

A patient's daughter asks the nurse, "What did the test results show? I know they were doing genetic testing on my mother." How should the nurse respond?

A) Refer the daughter to the patient's physician.

B) Review the patient's medical record with the daughter.

C) Ask the patient about the test results when the daughter enters the room.

D) Remind the daughter that private information cannot be discussed without the patient's permission.

somatic

U.S. gene therapy is limited to _____ cells only.

Pharmacogenetics

general term for the study of genetic variations in drug response and focuses on single-gene variations

Pharmacogenomics

-combination of two scientific disciplines: pharmacology and genomics

-Involves how genetics (genome) affect the body's response to drugs

-Individualized drug therapy based on a patient's genetic makeup