Nerotransmitter/Plasticity

A neurotransmitter communicates through:

Wired transmission

A neuromodulator communicates through:

Volume transmission

What neurotransmitter is made from acetyl-coA + choline?

Acetylecholine

What are your amino acid neurotransmitters? 

• Glutamate 

• Aspartate

• GABA

What amino acid neurotransmitter is derived from Glutamate?

Glycine

What neurotransmitter is a purine? 

ATP 

What neurotransmitters are derived from Tyrosine?

• Dopamine

• Norepinephrine

• Epinephrine

What neurotransmitters are derived from Tryptophan? 

• Serotonin (5-HT) 

• Histamine 

What neurotransmitters are catecholamines? 

• Epinephrine 

• Norepinephrine 

• Dopamine 

Primary excitatory neurotransmitters:

• ACH

• Glutamate

• Histamine

• ATP '

• Catecholamines

Primary inhibitory neurotransmitters:

• GABA

• Glycine

• Serotonin (5-HT)

What is the relationship between glial cells and glutamate?

Glial cells clear glutmate from the synaptic cleft, convert into glutamine, where it is then converted back into glutamate in the neuron.

GABA-A: 

Ligand gated chloride channel that reduced action potential probability. 

What are the primary neuromodulators? 

• Norepinephrine 

• Dopamine 

• Serotonin

• Acetylcholine 

• Histamine 

Where is Dopamine primarily produced? 

Substantia Nigra 

What is the most common catecholamine in the brain that has been preserved through evolution?

Dopamine

What are the two families of dopamine receptors?

• D1 (excitatory)

Increases cAMP and LTP; Low affinity receptors associated with high concentration of dopamine

• D2 (inhibitory)

Decreases cAMP and LTP; High affinity receptors associated with low concentration of dopamine