Appendix 1: CD Markers

This set contains practice questions regarding CD markers, their additional names, and the specific cell types that express them, based on the Appendix 1 CD Marker transcript.

Which CD marker is expressed by multiple cell types and is involved in the alternative presentation of lipid antigens?

$$CD1$$

What is the additional name for $CD2$ and which cells express it?

LFA-2; expressed by T cell and NK cells

Which cells express the $CD3$ marker?

T cells

On which cells is $CD4$ expressed, including the specific cell type where it is found at a low level?

T helper cells and low level on macrophages

Which cells express the $CD8$ marker?

Cytotoxic T cells

What is the additional name for $CD11a$ and which cell types express it?

LFA-1; B and T cells, granulocytes and monocytes/macrophages

What is the additional name for $CD11b$ and which cells express it?

MAC-1; myeloid and NK cells

Which cells express the $CD16$ marker?

neutrophils, NK cells, macrophages

Which cells express the $CD19$ marker?

B cells

Which cells express the $CD20$ marker?

B cells

Which cell types express the $CD21$ marker?

B cells and follicular dendritic cells

What is the additional name for $CD25$ and which cells express it?

IL-2R alpha chain; Activated B and T cells

Which cells express the $CD28$ marker?

T cells

Which cells express the $CD30$ marker?

Activated T, B, NK cells and monocytes

What is the additional name for $CD31$ and which cells express it?

PE-CAM 1; monocytes, granulocytes, T cell subsets and endothelial cells

Which cell types express the $CD40$ marker?

B cells, macrophages, and dendritic cells

What is the additional name for $CD46$ and what is its distribution?

MCP; expression is widely distributed (including non-immune cells)

Which cells express the $CD56$ marker?

NK cells

Which cells express the $CD69$ marker?

Activated T, B, NK cells and macrophages

Which cells specifically express the $CD77$ marker?

Germinal Center B cells

What is the additional name for $CD80$ and which cell types express it?

B7-1; Activated B cells, macrophages and dendritic cells

What is the additional name for $CD86$ and which cells express it?

B7-2; Activated B cells, macrophages and dendritic cells

What is the additional name for $CD95$ and which cells express it?

Fas; Activated T cells, B cells, NK cells, macrophages and monocytes

What is the additional name for $CD132$, which cells express it, and of which cytokine receptors is it a part?

common g chain; expressed by B, T, NK and mast cells, and neutrophils; part of the cytokine receptor for $IL-2$, $IL-4$, $IL-7$, $IL-9$ and $IL-15$

What is the additional name for $CD152$ and which cells express it?

CTLA-4; Activated T cells

What is the additional name for $CD154$ and which cells express it?

CD40 Ligand; Activated T cells

What is the additional name for $CD178$ and which cells express it?

Fas ligand; neutrophils, monocytes, and activated T cells and NK cells