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R etinal disparity
Retinal disparity (eyes are 2.5 inches apart)
Convergence
Convergence – things far away, eyes are relaxed. Things close to us, eyes contract.
relative size
relative size, interposition (overlap), relative height (things higher are farther away), shading and contour, motion parallax (things farther away move slower)
i nner ear muscle
Hearing - inner ear muscle: higher noise = contract.
just noticeable difference (JND)
The threshold at which you’re able to notice a change in any sensation is the just noticeable difference (JND)
Delta I/I = k
Delta I/I = k (Weber’s Law)
linear relationship
If we take Weber’s Law and rearrange it, we can see that it predicts a linear relationship bet
50%
The minimum intensity of stimulus needed to detect a particular stimulus 50% of the time
difference threshold (JND)
Not the same as the difference threshold (JND) – that’s the smallest difference that can be detected 50% of the time.
Subliminal
Subliminal stimuli – stimuli below the absolute threshold.
inner ear
Focus on inner ear - in particular the semicircular canals (posterior, lateral, and anterior)
endolymph
Canal is filled with endolymph, and causes it to shift – allows us to detect what direction our head is moving in, and the strength of rotation.
Otolithic organs
Otolithic organs (utricle and saccule) help us to detect linear acceleration and head positioning. In these are Ca crystals attached to hair cells in viscous gel. If we go from lying down to standing up, they move, and pull on hair cells which triggers AP.
Bottom up
Bottom up: stimulus influences our perception.
Top-down
Top-down: background knowledge influences perception. Ex. Where’s waldo
Conjunctiva
Conjunctiva is first layer light hits
Cornea
Cornea – transparent thick sheet of tissue, anterior 1/6th.
Anterior chamber
Anterior chamber – space filled with aqueous humour, which provides pressure to maintain shape of eyeball.
Pupil
Pupil is hole made by iris, which determines eye color
Lens
Lens bends the light so it goes to back of eyeball.
Suspensory ligaments
Suspensory ligaments, attached to a ciliary muscle. These two things together form the ciliary body, what secrets the aqueous humor.
Posterior chamber Is
Posterior chamber Is area behind the ciliary muscle, also filled with aqueous humor.
Vitreous chamber
Vitreous chamber – filled with vitreous humour, jelly-like substance to provide pressure to eyeball.
Retina
Retina is filled with photoreceptors.
Choroid
Choroid – pigmented black in humans, a network of blood vessels. Bc black all light is reflected.
Sclera
Sclera – whites of the eye, thick fibrous tissue that covers posterior 5/6th of eyeball. Attachment point for muscles.
light
Sensation requires light -> neural impulse, by a photoreceptor
rods
Light enters pupil and goes to retina, which contains rods and cones
rods,
There are 120 million rods, for night vision
cones
There are 6-7 million cones
fovea
Almost all cones are centered in fovea
Phototransduction Cascad
Phototransduction Cascade – when light hits rods and cones
off.
PTC is set of steps that turn it off.
rhodopsin,
A lot of proteins in the disks. One is rhodopsin, a multimeric protein with 7 discs, which contains a small molecule called retinal (11-cis retinal). When light hits, it can hit the retinal, and causes it to change conformation from bent to straight.
transducin
That begins this cascade of events – there’s a molecule in green called transducin made of 3 dif parts – alpha, beta, gamma
phosphodiesterase
Transducin breaks from rhodopsin, and alpha part comes to disk and binds to phosphodiesterase (PDE).
retinal ganglion cell
So bipolar cells turn on. This activates retinal ganglion cell which sends signal to optic nerve to brain.
Photoreceptors
Photoreceptors (Rods and Cones)
specialized nerve
A photoreceptor is a specialized nerve that can take light and convert to neural impulse.
optic discs
Inside rod are optic discs, which are large membrane bound structures – thousands of them. In membrane of each optic disc are proteins that fire APs to the brain.
Cones
Cones are also specialized nerves with same internal structure as rod.
Rods
Rods contain rhodopsin, cones have similar protein photopsin.
Rods are 1000x more sensitive to light
Rods are 1000x more sensitive to light than cones. Better at detecting light – telling us whether light is present, ie. BW vision
color
Cones are less sensitive but detect color (60% Red, 30% Green, 10% Blue)
blind spot
Where optic nerve connects to retina, blind spot – no cones or rods.
trich r omatic theory
Color (cones, trichromatic theory of color vision), form (parvocellular pathway – good at spatial resolution, but poor temporal), motion (magnocellular pathway, has high temporal resolution and poor spatial resolution, no color)
Parallel processing –
Parallel processing – see all at same time; simultaneous processing of incoming stimuli that differs in quality
pressurized sound wave
Need 1) pressurized sound wave and 2) hair cell
sound waves
Air molecules are pressurized and try to escape, creating areas of high and low pressure – known as sound waves
frequency.
How close peaks are is the frequency.
pinna
Hair cells – first hit outer part of ear, known as the pinna. Then go to external auditory meatus (aka auditory canal). Then hit the tympanic membrane (Eardrum)
malleus
As pressurized wave hits eardrum, it vibrates back and forth, causes these 3 bones to vibrate – malleus, incus, and stapes.
oval window
Stapes is attached to oval window (aka elliptical window). As it gets pushed, it pushes fluid and causes it to go around cochlea. At tip of cochea, it can only go back, but goes to the round window and pushes it out.
organ of Corti
Reason doesn’t go back to oval window, is because in middle of cochlea is a membrane – the organ of Corti (includes the basilar membrane and the tectorial membrane).
outer/external ear.
From pinna to tympanic membrane is the outer/external ear.
middle ear
From malleus to stapes, middle ear.
inner ear.
Cochlea and semicircular canals is the inner ear.
Stapes
Stapes – moving back and forth at same frequency as stimulus. It pushes the elliptical window back and forth.
. Organ of Corti
There’s fluid inside the cochlea which gets pushed around cochlea, and comes back around. Organ of Corti splits cochlea into 2.
Organ of Corti
Cross section of Organ of Corti
Upper and lower membrane
Upper and lower membrane, and little hair cells. As fluid flows around the organ it causes hair cells to move back and forth.
hair bundle
The hair bundle is made of little filaments. Each filament is called a kinocilium.
tip link
Tip of each kinocilium is connected by a tip link.
K channel
Tip link is attached to gate of K channel, so when get pushed back and forth they stretch and allows K to flow inside the cell.
spiral ganglion cell
Ca cells get activated when K is inside, so Ca also gets activated, and causes AP in a spiral ganglion cell which then activates the auditory nerve.
cochlea
Brain relies on cochlea to differentiate between 2 different sounds.
basilar tuning –
Brain also uses basilar tuning – there are varying hair cells in cochlea. Hair cells at base of cochlea are activated by high frequency sounds, and those at apex by low frequency sounds.
primary auditory cortex
Only certain hair cells are activated and send AP to the brain – primary auditory cortex receives all info from cochlea.
tonotypical mapping
So with basilar tuning, brain can distinguish dif frequencies – tonotypical mapping.
sensory narrow hearing loss
A surgical procedure that attempts to restore some degree of hearing to individuals with sensory narrow hearing loss – aka nerve deafness
Receiver
Receiver goes to a stimulator which reaches the cochlea. Receiver receives info from a transmitter. Transmitter gets electrical info from the speech processor. Speech processor gets info from microphone.
Types:
Types: Temperature (thermoception), pressure (mechanoception), pain (nociception), and position (proprioception)
Timing:
Timing: Non-adapting, slow-adapting, fast-adapting.
Location:
Location: Location-specific nerves to brain
Adaptation
Adaptation is change over time of receptor to a constant stimulus – downregulation
A mplification
Amplification is upregulation
sensory cortex
This part of cortex is the sensory cortex – contains the homunculus.
proprioception
How can you walk in a pitch black room? You rely on your sense of balance/position –proprioception.
Kinaesthesia
Kinaesthesia is talking about movement of the body. Proprioception was cognitive awareness of body in space. Kinaesthesia is more behavioural.
TrypV1 receptor
In order for us to sense temperature, we rely on the TrypV1 receptor.
conformational change
There are thousands of these in membranes. Heat causes a conformational change in the protein.
3 types of fibres
3 types of fibres – fast, medium, slow.
A-beta fibres -
A-beta fibres - Fast ones are thick and covered in myelin (less resistance, high conductance)
A-delta fibres
A-delta fibres -– smaller diameter, less myelin.
C fibres
C fibres - small diameter, unmyelinated (lingering sense of pain).
Olfaction
Olfaction – Structure and Function
olfaction
Smell is also known as olfaction
olfactory epithelium
Area in nostril called the olfactory epithelium. Separating the olfactory epithelium from the brain is the cribriform plate. Above the plate is an extension from the brain – olfactory bulb – a bundle of nerves that sends little projections through cribriform plate into the olfactory epithelium, which branch off.
olfactory bulb
Zoom in on olfactory bulb
glomerulus
When it binds to receptor, triggers events that cause cell to fire. AP will end up in olfactory bulb. All cells sensitive to benzene will fire to one olfactory bulb – called a glomerulus.
mitral/tufted cell
They then synapse on another cell known as a mitral/tufted cell that projects to the brain.
pheromones
Why do dogs pee on fire hydrant? There are molecules released in the urine, which can be sensed by other animals through the nose – pheromones.
innate response
Pheromone is a chemical signal released by 1 member of the species and sensed by another species to trigger an innate response.
accessory olfactory epithelium
Specialized part of olfactory epithelium in animals – the accessory olfactory epithelium. It sends projections to the accessory olfactory bulb.
vomeronasal system.
Within the accessory olfactory epithelium, you have the vomeronasal system.
basal cells
In vomeronasal system, there are basal cells and apical cells. They have receptors at tips.
amygdala.
Triangle will come in and activate receptor on basal cell here. Basal cell sends axon through accessory olfactory bulb to glomerulus, which eventually goes to the amygdala.
Humans
Humans have vomeronasal organ, but no accessory olfactory bulb.
Gustation
Gustation – Structure and Function
fungiform
Taste buds are concentrated anteriorly on the tongue. Taste buds can be fungiform (anterior), foliate (side), and circumvallate (back).