Microbiology - Mechanisms of Drugs

Amoxicillin

inhibition of cell wall synthesis

Cefazolin

inhibition of cell wall synthesis

Doripenem

Inhibition of cell wall synthesis

Vancomycin

inhibition of cell wall synthesis

Streptomycin

inhibition of protein synthesis

Tetracycline

inhibition of protein synthesis

Azithromycin

inhibition of protein synthesis

Linezolid

inhibition of protein synthesis

Sulfamethoxazole-trimethoprim

inhibition of folic acid synthesis

Ciprofloxacin

Inhibition of DNA or RNA replication or synthesis

Polymyxin B

Disruption of cytoplasmic membrane

Amphotericin B

bind to fungal membranes, causing loss of selective permeability

Nystatin

bind to fungal membranes causing loss of selective permeability

Ketoconazole

interferes with sterol synthesis

Fluconazole

interferes with sterol synthesis

Caspofungin

inhibit fungal cell wall synthesis

Terbinafine

inhibit enzyme critical for ergosterol synthesis

Microfungin

inhibit fungal cell wall synthesis

Miconazole

interferes with sterol synthesis

Clortrimazole

interferes with sterol synthesis

Penicillin

inhibition of cell wall synthesis

Ceftriaxone

inhibition of cell wall synthesis

Isoniazid

inhibition of cell wall synthesis

Rifampin

Inhibition of DNA or RNA replication or synthesis

Quinine

treats malaria

Artemisinin

treats malaria

Metronidazole

treats bacterial/protozoal infections; treats BV

Mebendazole

microtubule inhibition of helminths

Pyrantel

treats helminthic infections

Ivermectin

treats helminthic infections

Amantadine

treats viral infections

Acyclovir

Treats viral infections

Ribavirin

treats viral infections

Zidovudine (AZT)

treats viral infections

Mechanism of Acyclovir

inhibits viral nucleic acid synthesis

Mechanism of ribavirin

inhibit nucleic acid synthesis

mechanism of zidovudine (AZT)

inhibits nucleic acid synthesis

Zanamivir

treats viral infection

Oseltamivir

treats viral infection

mechanism of zanamivir

inhibition of viral release

Mechanism of oseltamivir

inhibition of viral release

mechanism of quinine

interferes with digestion of hemoglobin

mechanism of artemisinin

produces free radicals and poisons proteins

mechanism of chloroquin

interferes with digestion of hemoglobin

mechanism of primaquin

interferes with digestion of hemoglobin

mechanism of albendazole

microtubule inhibition of helminths

mechanism of quinacrine

inhibit transcription and translation of DNA & interfere with cellular energy

mechanism of metronidazole

oxidized parasite DNA