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A comprehensive set of vocabulary flashcards covering microscopes, cells, cell theory, specialized cells, the cell cycle (mitosis & meiosis), and cellular transport.
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Microscope
A scientific instrument that magnifies objects to reveal details not visible to the naked eye.
Light Microscope
An optical microscope that uses lenses to focus visible light on specimens to magnify them.
Magnification
The apparent enlargement of an object, produced by objective and eyepiece lenses (e.g., 100x × 10x = 1000x).
Resolution
The ability to distinguish fine detail; how well two close objects can be seen as separate.
Contrast
The difference in brightness between the specimen and its background, often enhanced by staining.
Head (body)
The upper part of a microscope that contains the optical components.
Base
The bottom support of the microscope; may contain the illumination source.
Arm
The component that connects the base to the head and stage; used to carry the microscope.
Eyepiece
The lens through which you look to view the specimen.
Eyepiece Tube
The tube that holds the eyepiece and is mounted above the objective lens.
Objective Lenses
Primary lenses (e.g., 40x–100x) used to form the initial magnified image.
Nosepiece
Rotating part that holds multiple objective lenses and selects magnification.
Coarse Adjustment Knob
Large knob for coarse focus adjustment.
Fine Adjustment Knob
Small knob for precise focusing.
Stage
Platform where the slide sits; held by stage clips.
Stage Clips
Clips that secure the slide on the stage.
Illuminator
Light source at the base that provides illumination for viewing.
Condenser
Lenses under the stage that focus light through the specimen.
Diaphragm
Controls the amount of light reaching the specimen.
Electron Microscope
A microscope that uses a beam of accelerated electrons for high-resolution images.
Electron Gun
A heated filament that emits electrons.
Electromagnetic Lenses
Magnetic lenses that focus the electron beam (condenser, objective, projector/ocular).
Specimen Holder
A very thin film support (carbon/collodion on a grid) for the specimen.
Image Viewing and Recording System
Display and recording setup (fluorescent screen and camera) for the final image.
Ernst Ruska
German engineer who built the first electron microscope in 1931.
Hans Janssen
Dutch father who, with his son, helped develop early microscopes by combining lenses.
Zacharias Janssen
Dutch son who collaborated on early microscope creation.
Antonie van Leeuwenhoek
Dutch scientist who built a simple microscope and observed bacteria and protozoa (animalcules).
Cells
The fundamental unit of life; basic structural and functional unit of living organisms.
Cell Theory
Idea that organisms are composed of cells; cells are the basic units of life; all cells arise from preexisting cells.
Postulates
Three original cell theory statements: all organisms are made of cells; cells are the basic unit of life; all cells come from preexisting cells.
DNA
Deoxyribonucleic acid; hereditary material passed between cells.
Nucleus
The control center of the cell containing DNA and regulating cellular activities.
Nucleolus
Dense region inside the nucleus that produces ribosomes.
Cytoplasm
Jelly-like interior of the cell that houses organelles.
Mitochondria
Powerhouses of the cell; generate ATP (cellular energy).
Ribosomes
Tiny particles that synthesize proteins.
Endoplasmic Reticulum (ER)
Membrane network for protein and lipid synthesis; Rough ER has ribosomes; Smooth ER lacks ribosomes.
Golgi Apparatus
Organelle that sorts, modifies, and packages proteins and lipids for transport.
Lysosomes
Digestive organelles that break down waste and worn-out parts.
Cytoskeleton
Network of protein filaments providing structure, shape, and transport within the cell.
Centrioles
Structures involved in organizing microtubules during cell division.
Vesicle
Small sacs that transport materials inside the cell or to the membrane.
Cell Membrane
Semi-permeable boundary that controls entry and exit of substances.
Chloroplasts
Plant organelles where photosynthesis occurs; contain chlorophyll.
Cell Wall
Rigid outer layer (mainly cellulose in plants) providing support and protection.
Plastids
Plant organelles involved in storage and manufacturing of food; includes chloroplasts.
Prokaryotic Cell
Single-celled organism lacking a membrane-bound nucleus and other organelles; divide by binary fission (e.g., bacteria).
Capsule
Protective outer layer in some bacteria that aids moisture retention and adherence.
Pili
Hair-like structures on bacteria that help attach to surfaces.
Fimbriae
Shorter appendages (pili) that help bacteria attach to surfaces.
Flagella
Long, whip-like structures that enable bacterial movement.
Plasmids
Small, circular DNA molecules outside the chromosome that carry genes.
Nucleoid
Region in a prokaryotic cell containing the single circular chromosome.
Red Blood Cell
Disc-shaped, anucleate cell in mammals that carries hemoglobin for oxygen transport.
Root Hair Cell
Plant root cell with elongated extensions to increase surface area for absorption.
Xylem
Plant tissue that transports water and minerals; composed of lignified, dead cells.
Phloem
Plant tissue that transports sugars; includes sieve tubes and companion cells.
Guard Cells
Cells that regulate stomatal opening via changes in turgor pressure.
Palisade Cell
Photosynthetic plant cell rich in chloroplasts and oriented to maximize light absorption.
Sperm Cell
Male gamete; contains acrosome on head and mitochondria in the tail; fertilizes the egg.
Egg Cell
Large female gamete rich in nutrients; contributes half the genetic material.
Ciliated Cells
Cells bearing cilia that move mucus or eggs through passages.
Meiosis
Cell division that reduces chromosome number from diploid to haploid to form gametes.
Mitosis
Nuclear division producing two genetically identical diploid daughter cells.
Interphase
Longest cell cycle stage; cell grows and DNA is replicated.
G1 Phase
First gap phase; cell growth and normal metabolism occur.
S Phase
DNA synthesis and replication; sister chromatids form.
G2 Phase
Second gap phase; further growth and preparation for division; DNA checked.
Prophase
Chromosomes condense; nuclear envelope dissolves; spindle forms.
Metaphase
Chromosomes align at the cell equator; spindle fibers attach to centromeres.
Anaphase
Sister chromatids separate and move to opposite poles.
Telophase
Chromosomes arrive at poles and decondense; new nuclear envelopes form.
Cytokinesis
Division of the cytoplasm, producing two distinct daughter cells.
Crossing Over
Exchange of DNA between homologous chromosomes in Prophase I, increasing genetic variation.
Non-Disjunction
Failure of chromosome/chromatid separation during meiosis, producing abnormal gametes.
Down Syndrome
Trisomy 21; an extra chromosome 21 in each cell.
Turner Syndrome
45,X; monosomy of the X chromosome in females.
Klinefelter Syndrome
47,XXY; male with extra X chromosome.
Cri du Chat
Deletion on chromosome 5 leading to a characteristic cry and developmental issues.
Osmosis
Diffusion of water across a selectively permeable membrane from hypotonic to hypertonic solutions.
Diffusion
Movement of particles from high to low concentration due to random motion.
Isotonic
Solution with equal solute concentration to the cell’s cytoplasm; no net water movement.
Hypertonic
Solution with higher solute concentration than the cell’s cytoplasm; water leaves the cell.
Hypotonic
Solution with lower solute concentration than the cell’s cytoplasm; water enters the cell.
Facilitated Diffusion
Passive transport of molecules via membrane proteins down the concentration gradient.
Channel Proteins
Membrane proteins forming pores for specific ions or molecules to pass.
Carrier Proteins
Membrane proteins that bind a molecule and shuttle it across the membrane.
Active Transport
Movement of solutes against the concentration gradient requiring energy (ATP).
ATP
Adenosine triphosphate; the energy currency of the cell.
Endocytosis
Cellular uptake of materials by engulfing them with the plasma membrane.
Phagocytosis
Endocytosis of solid material (cellular eating) by engulfment.
Pinocytosis
Endocytosis of liquids (cellular drinking) via vesicle formation.