Unit 5.4 - AP Biology

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Loci

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10 Terms

1

Loci

plural form of locus (positions)

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2

Morgan’s experiments:

  • he noted wild-type (normal) phenotypes that were common in the fly populations

  • Traits alternative to the wild type are called mutant phenotypes

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3

Chromosomal Basics of Gender

  • humans (and other mammals) have 2 types of sex chromosomes: X and Y (all other chromosomes are autosomes)

    • two X chromosomes associated w/ female anatomy

    • One X and one Y chromosome associated w/ male anatomy

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4

Crossing can happen in males

  • ends of the Y chromosome have regions that are homologous w/ corresponding regions of X chromosome so they can pair and behave like homologs during meiosis in males

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5

Sex- linked inheritance

  • a gene that is located on either sex chromosome is called a sex-linked gene— either X-linked or Y-linked

    • many y- linked genes help determine male gender

    • X- chromosome have genes for many other traits

  • For a recessive X lined trait to be expressed:

    • females need 2 copies of the allele (homozygous)

    • Males need only 1 copy of the allele (hemizygous)

  • Ex. Color blindness and hemophilia

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6

X inactivation in female mammals

In mammalian females, one of the two X chromosomes is randomly inactivated during embryonic development which condenses into a Barr body

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7

Abnormal chromosome number

  • nondisjunction occurs when pairs of homologous chromosomes (or sister chromatids) do not separate normally during meiosis I or II

  • As a result, 1 gamete receives 2 of the same type of chromosome, and another gamete receives no copy

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8

Aneuploidy

Fertilization after no disjunction results in aneuploidy (abnormal number of chromosomes)

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9

Polyploid

  • a condition in which an organism has more than two complete sets of chromosomes

    • Triploidy (3n) is three sets of chromosomes

    • Tetraploidy (4n) is four sets of chromosomes

  • Only common in plants

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10

Pedigrees

Family tree that contains a family’s history for a particular trait across generations

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