HLTH 217 - Gluconeogenesis

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6 Terms

1
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Is it anabolic or catabolic?

Overall an anabolic reaction because you are taking smaller molecules such as pyruvate to make glucose

2
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Why is gluconeogenesis not a complete reversal of glycolysis?

Several reactions differ because the equilibrium of glycolysis lies far on the side of pyruvate formation. 

Specifics:

3
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What happens in most cases of gluceogenesis ending

It ends with glucose 6-phosphate cause free glucose can be generated as most tissues lack the enzyme glucose 6-phosphatatse. It instead be converted into glycogen or used for biosynthesis of other molecules eg nucleotides. 

4
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Liver glycolysis/gluceogenesis regulation  

5
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What is the key regulation site of gluconeogensis pathway

coversion of furctose 6-phosphate to fructose 1,6-biphosphate.

6
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How is glycolysis/gluconeogenesis controlled in the liver?

Hormones that are sensitive to blood-glucose concentration. the concentration of fructose 2,6-biphosphate acticates or inhibits enzymes to slow or speed up

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