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Temperature, humidity, and light
Factors that affect medication stability.
Drug integrity
Maintaining the purity and efficacy of medications.
Package label
Source where storage requirements can be found.
Room temperature range (Celsius)
20°C to 25°C.
Room temperature range (Fahrenheit)
68°F to 77°F.
Refrigerator temperature range (Celsius)
1.7°C to 7.8°C.
Refrigerator temperature range (Fahrenheit)
35°F to 46°F.
Freezer temperature
−15°C (5°F) or lower.
Temperature checks by pharmacy staff
Performed twice daily.
Formula to convert Celsius to Fahrenheit
F = (9/5 × C) + 32.
Formula to convert Fahrenheit to Celsius
C = (F − 32) × 5/9.
First step if medication is stored incorrectly
Move to proper storage immediately.
Second step if medication is stored incorrectly
Assess impact on drug efficacy.
Third step if medication is stored incorrectly
Notify pharmacist.
Fourth step if medication is stored incorrectly
Review storage protocols with staff.
Fifth step if medication is stored incorrectly
Inspect storage areas regularly.
Nitroglycerin storage requirement
Must be kept in original amber bottle.
Why nitroglycerin stays in original bottle
Sensitive to light and humidity.
Medications that require refrigeration
Examples include Latanoprost, insulin, vaginal rings, promethazine suppositories.
Antibiotic powders before reconstitution
Stored at room temperature.
Antibiotic powders after reconstitution
May require refrigeration.
Communication in pharmacy
A soft skill requiring adaptability, respect, and cultural awareness.
External customers in pharmacy
Patients and caregivers.
Internal customers in pharmacy
Staff and healthcare professionals.
Adaptability in communication
Adjusting communication style based on the audience.
How to communicate with healthcare professionals
Use medical terminology.
How to communicate with patients
Use plain language and avoid complex terms.
Why plain language is important
Improves understanding and patient engagement.
Respect in healthcare
Treating all patients with dignity regardless of background.
Examples of patient diversity
Age, race, religion, gender identity, sexual orientation, medical condition.
How to show respect to patients
Active listening, empathy, involving them in decisions.
Why mutual respect matters in pharmacy
Improves teamwork, work culture, and job satisfaction.
Professional communication tip
Limit medical terminology when speaking to patients.
Cultural sensitivity
Awareness and respect for different cultural beliefs.
Why cultural sensitivity matters
Helps provide culturally competent care.
Demonstrating cultural sensitivity
Avoiding judgment and respecting differences.
Clinical empathy
Understanding and sharing patient feelings while staying professional.
How to show clinical empathy
Active listening, acknowledging emotions, showing compassion.
Why clinical empathy matters
Builds trust and improves patient satisfaction.
Example of empathy in pharmacy
Listening to patient concerns and asking respectful questions.
Who answers clinical questions
Pharmacist.
Best example of cultural awareness in pharmacy
Tailoring communication about birth control respectfully.
What is NOT respectful behavior in pharmacy communication
Ignoring patient concerns or pronouns.
What is unethical behavior in pharmacy communication
Dismissing patient concerns based on personal beliefs.
Controlled Substances Act (CSA)
Federal law regulating controlled substances.
Who enforces CSA
Drug Enforcement Administration (DEA).
DEA Form 222 purpose
Used to order C-II medications.
DEA Form 222 format
Triplicate paper form.
Who signs DEA Form 222
Pharmacist or power of attorney.
Where copies of Form 222 go
Supplier, DEA, pharmacy.
How long Form 222 is valid
60 days.
How long Form 222 must be kept
2 years.
CSOS (Controlled Substance Ordering System)
Electronic system to order C-II medications.
Advantage of CSOS
Faster ordering with electronic signature.
Which schedules require Form 222
C-II only.
Which schedules do NOT require Form 222
C-III to C-V.
DEA Form 41 purpose
Disposal of controlled substances.
When Form 41 is used
Expired, damaged, or unused meds.
How controlled substances can be disposed
Manufacturer, wholesaler, reverse distributor.
DEA Form 106 purpose
Report theft or loss of controlled substances.
Who is responsible for reporting theft
Pharmacist.
Technician role in theft situations
Gather inventory/count information.
Controlled substance inventory requirement
Every 2 years.
How long inventory records must be kept
2 years.
C-II inventory requirement
Exact count required.
C-III to C-V inventory requirement
May estimate.
Perpetual inventory log
Ongoing record of controlled substances.
Who updates perpetual inventory
Technician.
Who verifies perpetual inventory
Pharmacist.
C-II prescription filing requirement
Must be filed separately.
C-III to C-V filing options
With non-controlled (with red 'C') or separate file.
Controlled substance lending between pharmacies
Allowed under specific rules.
Requirement for lending controlled substances
Both pharmacies must be DEA registered.
Form used for lending controlled substances
DEA Form 222.
Max amount that can be lent
5% of annual supply.
Example of 5% rule
1,000 tablets → max 50 tablets can be lent.
How to verify prescriber legitimacy
Check DEA number.
What to do if prescription seems fraudulent
Notify pharmacist immediately.
How can C-II meds be ordered?
Electronically (CSOS) or paper (Form 222).
Can C-II meds be ordered by phone or fax?
No.
Form 222
Used to order C-II.
Form 41
Used for disposal.
Form 106
Used to report theft or loss.
C-II
Requires exact count and separate file.
Inventory
Conducted every 2 years.
Max transfer
5% of annual supply.
Inpatient pharmacy
Pharmacy within a hospital or health system.
Key difference in inpatient setting
DEA number not required on prescription.
Why DEA number isn’t required inpatient
Hospital keeps prescriber DEA numbers on file.
Do inpatient pharmacies follow CSA laws?
Yes, most laws still apply.
Basic prescription components
Drug name, strength, dosage form, route, directions, quantity.
Additional CSA-required components
Patient info, prescriber info, DEA number, date, refills, signature.
Patient information required
Full name and full street address.
Prescriber information required
Name, address, phone number, DEA number.
Exception (inpatient)
DEA number not required on prescription.
Prescription must include date
Date issued by prescriber.
Prescription must include refills
Number of refills authorized.
Prescription must include signature
Prescriber’s signature.
Why controlled substance prescriptions are high risk
High abuse potential.
Examples of fraudulent prescriptions
Stolen prescription pads, fake prescriber names, invalid DEA numbers, altered phone numbers.