Sx drugs

what kind of drug is Acepromazine

phenothiazine tranquilizer

what are the adverse effects/disadvantages of acepromazine

CNS depression without calming, hypotension → hypothermia

no reversal, no analgesia, metabolized by liver, no sight hounds/MDR-1/boxers

what kind of drug is carprofen

NSAID

what are the adverse effects of carprofen

Gi upset, hepatotoxicity

what kind of drug is diazepam

benzodiazepine tranquilizer

what are the advantages of diazepam

minimal cardiovascular depression, produces muscle relaxation along with sedative effects, rapid anticonvulsant effects

what can reverse benzodiazepine tranqulizers

flumazenil

what are the disadvantages of benzodiazepine tranquilizers

excitatory effects in young animals, caution with animal with hepatic disease

what is another name for diazepam

valium

what is the MOA for diazepam

potentiates GABA

what route must diazepam be given

IV

what is another name of midazolam

versed

what kind of drug is midazolam

benzodiazepine tranquilizer

t/f midazolam is more likely to cause respiratory depression than diazepam

true

what are the advantages of acepromazine

significant sedation, anti-emetic properties, antiarrhythmic properties

what kind of drug is dexmedetomidine

alpha 2 agonist

what can reverse dexdomitor

Atipamezole/antisedan

what kind of drug is buprenorphine

partial mu agonist, kappa antagonist

is buprenorphine hard or easy to reverse

difficult

what can happen with buprenorphine due to partial agonism

ceiling effect

what kind of drug is ketamine

cyclohexamine

what is the main effects of ketamine

catalepsy (loss of consciousness and muscle rigidity), amnesia, mild analgesia

what is the MOA of ketamine

inhibit the NMDA receptor in CNS (reduces wind up effect)

what is a disadvantage of ketamine

apneustic breathing, increases ICP, seizure-like state

what is the MOA of propofol

stimulates GABA

what are the adverse effects of propofol

apnea, hypotension, decreased cardiac output

what is the use of ephedrine

short term boost in cardiac output and blood pressure

what kind of antiarrhythmic is lidocaine

membrane stabilizer

what rhythm is lidocaine used for

ventricular arrhythmias