Biologics IOT Study Guide – Vocabulary Review

Vocabulary flashcards summarizing essential terms, products, and concepts from the Biologics IOT lecture.

PRP/BMAC viability without ACD-A

Remains effective for ~30 minutes once drawn if ACD-A anticoagulant is not added.

ACD-A working time

Provides anticoagulation for up to 4 hours after collection.

AlloSync DBM key benefits

Terminal sterility, superior handling, room-temperature storage, and lot-specific sterility testing.

AlloSync role in the bone-healing triad

Supplies an osteoconductive scaffold and osteoinductive growth-factor signals.

BMAC versus PRP

BMAC contains higher levels of white blood cells, platelets, and IRAP compared with PRP.

AlloSync demineralized sponges composition

Manufactured from 100 % cancellous bone.

JumpStart microcell battery chemistry

Powered by silver-and-zinc batteries.

Drill sizes for AlloSync PIP instrumentation

Uses 2.5 mm, 2.7 mm, and 3.0 mm drills; implant size 3 mm × 22 mm.

Suture-retaining amnion product

Cord amnion can hold a stitch.

Erythrocytes

Red blood cells, composing roughly 55 % of whole blood volume.

WHAT GIVES ALLOSYNC PURE RESISTANCE TO IRRIGATION

Rice-Shaped Fiber Technology

Preferred biologic for nonunion/fracture

DBM mixed with autologous blood, PRP, or BMAC, or the cellular allograft ArthroCell.

BioCartilage-to-blood mixing ratio

1 part BioCartilage to 0.8 parts blood (1 : 0.8).

Amnion graft benefits

Rich in growth factors

serves as an adhesion barrier

reduces inflammation and scarring

is antimicrobial.

Typical sites of talar OCDs

Anterolateral and posteromedial portions of the talus.

Cotton osteotomy target bone

Performed on the medial cuneiform.

Bone products containing 100 % DBM

AlloSync Cortical Fibers

AlloSync Expand

AlloSync Pure

AlloSync Cancellous Sponges.

MIAMI cells

Marrow-Isolated Adult Multi-lineage Inducible cells found in ArthroCell.

Allografts providing cell, signal, and scaffold

ArthroCell and BioSurge deliver living cells, osteoinductive signals, and an osteoconductive scaffold.

Shelf life of Cotton and Evans wedges

3 years at room temperature.

AlloSync products with 5-year shelf life

AlloSync Pure, Expand, Cancellous Sponges, and Cortical Fibers retain sterility for up to 5 years.