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ATP
Body’s universal energy currency - broken down to release energy
Exothermic
A reaction which produces energy and releases heat
Endothermic
A reaction which uses energy
Coupled Reaction
The product from one reaction is used as a reactant in another reaction
Sarcoplasm
Located in muscles - the site of the ATP/PC system and the lactic acid system
Mitochondria
The site of aerobic respiration
Lactic Acid
A harmful by-product which causes muscle pain and fatigue
Enzyme
An organism that catalyses a reaction
Resynthesis
Builds back up
Energy Continuum
The relative contribution of each energy system to overall energy production
Intermittent exercise
Exercise which varie
Adenosine Triphosphate
one adenosine molecule and 3 phosphate molecules
the energy stored in the phosphate bonds is released to cause muscular contractions
ATP breakdown
The chemical reaction which causes the molecules to split - enzyme ATPase
Exothermic (releases energy to the muscles) - 2/3 seconds
ATP = ADP + P + energy
ADP = Adenosine diphosphate (1 mol adenosine and 2 mol phosphate )
ATP resynthesis
ADP + P + energy = ATP (endothermic)
To replace the bond between two molecules, an energy is required from an alternative source - endothermic
COUPLED REACTION – continual breakdown and resynthesis of ATP
ATP/PC system
Phosphocreatine(PC) - stored in the sarcoplasm - broken down with the enzyme Creatine Kinase - makes creatine and phosphate – this phosphate is the P in the reaction
The phosphate lost in the breakdown goes back into the phosphocreatine stores
High intensity (under 10 second)
Immediately available
No harmful by-products
Type 2b – Fast Glycolytic – high phosphocreatine stores
Glycolytic system
Used when the ATP/PC system is exhausted
Glucose is the next source of energy available to resynthesis ATP
Triggered by the rise of ADP in muscle cells
GPP = Glucose Phosphorylase
Glycogen breaks down to glucose - enzyme GPP
Glucose breaks down to pyruvic acid/ pyruvate - enzyme PFK - releases 2mol energy (pyruvate)
In high intensity exercise and during the early phases of ATP resynthesis, oxygen is not available
Lactate Dehydrogenase only appears without oxygen (anaerobic respiration)
Pyruvic acid combines with the enzyme LDH - produces lactic acid
Lasts for around 3 minutes at moderate intensity
Impact of lactic acid
inhibits the release of enzymes and causes pain receptors in the muscles to be stimulated
Aerobic system
Aerobic Glycolysis
Krebs cycle
Electron Transfer Chain
At rest the main system is the aerobic system – plentiful supply of oxygen
Aerobic glycolysis
Glucose breaks down to glycogen - enzyme GPP
Glycogen breaks down to pyruvic acid/ pyruvate - enzyme PFK
Krebs cycle
Pyruvate breaks down to acetyl COA - enzyme Coenzyme A
This combines with oxaloacetic acid to create citric acid
Citric acid gets oxidised – carbon dioxide is released as a bi-product
The resynthesis of 2 ATP moles can then happen
This occurs in the matrix of the mitochondria
Hydrogen atoms are removed and transported to the cristae of the mitochondria
By the hydrogen carriers NAD and FAD
Electron transport chain
Cristae of the mitochondria
Hydrogen atoms are split into ions and electrons
Some ions are oxidised and released as H2O
Pairs of hydrogen ions carried by NAD release enough energy to resynthesis 30 ATP
FAD carries enough pairs to resynthesis another 4 molecules of ATP
= 38 moles of ATP are produced from 1 mole of glucose
ATP/PC advantages
No oxygen
• Quick energy supply
•Good for powerful/ explosive work
• Quick recovery
Glycolytic advantages
Large glycogen store
• 2 ATP produced per molecule
• Fewer reactions
• Good for intense work
Aerobic advantages
Large glycogen and fat stores
• 38 ATP per molecule
• No fatigue
• Good for endurance
ATP/PC disadvantages
Small energy yield – 1 mole
• Limited duration
• Only a small amount is stored
Glycolytic disadvantages
Slower than ATP/PC
• Produces lactic acid
• Stimulates pain receptors
• Early fatigue
• Slow recovery
Aerobic disadvantages
Slow to metabolise
• Complex reactions
• Slow to engage – requires oxygen
• No use for explosive movement
• Complexed recovery
ATP/PC facts
ATP/PC
Sarcoplasm
High intensity
1:1 yield
ATPase/ Creatine Kinase
Glycolytic facts
Glycogen/ Glucose
Sarcoplasm
High - moderate intensity
2:1 yield
PFK/LDH
LDH facts
Glycogen/ Fat
Mitochondria - matrix for Krebs and cristae for ETC
Moderate - low intensity
38:1 yield
PFK/ GPP
EPOC
Excess Post-Exercise Oxygen Consumption
Alactacid component
PC stores are restored
3 minutes to recover fully, 30 seconds for 50%, and 60 seconds for 75%
Requires 1-4L of oxygen
Replenishment of blood and muscle oxygen
Within 1 minute, oxygen resaturates the bloodstream - associates with haemoglobin
Within 3 minutes, the oxygen link to muscle cells is restored
Alactacid component
PC stores are restored
3 minutes to recover fully, 30 seconds for 50%, and 60 seconds for 75%
Requires 1-4L of oxygen
Replenishment of blood and muscle oxygen
Within 1 minute, oxygen resaturates the bloodstream - associates with haemoglobin
Within 3 minutes, the oxygen link to muscle cells is restored
Lactacid component
needs 5-8 litres of O2
takes hours to complete
Elevated ventilation and circulation
Respiratory rate, depth, and HR remain elevated - gradually decrease to maximise O2 delivery, and bi-product removal
Elevated body temperature
Increases metabolic rate - 60-70% of the slow lactacid component
Removal of lactic acid
50-75% is converted back into pyruvic acid and used in the Krebs Cycle
10-25% is converted back to glucose
Can be converted to proteins by the Cori Cycle
Can be removed via sweating and in urine
Maximising recovery
Warm Up = minimise time spent using anaerobic aerobic system - reduces oxygen deficit
Active Recovery = maintains respiratory rate, and HR - speeds up the removal of lactic acid
Cooling Aids = used post-event to speed up the removal of lactic acid and to reduce muscle soreness and DOMS - ice baths
Intensity of Training = high intensity training will increase ATP/PC storage - boosts efficiency of the fast component, increases tolerance of lactic acid and buffering capacity, and delays OBLA - reduces demand on the slow component. Low intensity exercise will increase aerobic capacity - delays OBLA - maximises oxygen delivery to working muscles - higher intensity takes longer to recover, and low intensity allows for a faster recovery
Work:Relief Ratios = can maximise recovery - 1:1 /1:2 / 1:3
Strategies and Tactics = using time-outs and substitutions - delays OBLA and fatigue
Nutrition = maximise fuel stores - delays fatigue - reduces lactic acid - speeds up recovery - creatine supplements